AutismKB 2.0

Annotation Detail for MAPK8IP3


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Basic Information Top
Gene Symbol:MAPK8IP3 ( DKFZp762N1113,FLJ00027,JIP3,JSAP1,KIAA1066,SYD2,syd )
Gene Full Name: mitogen-activated protein kinase 8 interacting protein 3
Band: 16p13.3
Quick LinksEntrez ID:23162; OMIM: 605431; Uniprot ID:JIP3_HUMAN; ENSEMBL ID: ENSG00000138834; HGNC ID: 6884
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body13 / 70761183
blastocyst3 / 6231948
fetus23 / 56401240
neonate0 / 310970 
infant1 / 2362042
juvenile3 / 5555653
adult156 / 193912180
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma1 / 1747557
breast (mammary gland) tumor4 / 9417842
cervical tumor0 / 343660 
chondrosarcoma7 / 8282384
colorectal tumor15 / 114246131
esophageal tumor1 / 1729057
gastrointestinal tumor10 / 11936983
germ cell tumor2 / 2638457
glioma5 / 10688346
head and neck tumor3 / 13630222
kidney tumor2 / 6895929
leukemia10 / 95842104
liver tumor0 / 963590 
lung tumor5 / 10312748
lymphoma0 / 717550 
non-neoplasia8 / 9725082
normal181 / 336030753
ovarian tumor2 / 7668226
pancreatic tumor7 / 10461666
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer5 / 10268048
retinoblastoma0 / 463560 
skin tumor2 / 12494916
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder1 / 2975733
blood7 / 12347856
bone6 / 7165583
bone marrow2 / 4880140
brain49 / 110098944
cervix0 / 481710 
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue18 / 21572283
esophagus1 / 2020949
eye19 / 21105490
heart1 / 8962611
intestine24 / 234472102
kidney3 / 21177714
larynx1 / 2414541
liver0 / 2077430 
lung24 / 33697471
lymph0 / 442700 
lymph node16 / 91610174
mammary gland6 / 15327139
mouth1 / 6705214
muscle1 / 1077159
nerve3 / 15768190
ovary2 / 10205119
pancreas13 / 21481260
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta13 / 28082546
prostate8 / 18934542
salivary gland0 / 201550 
skin4 / 21057418
spleen3 / 5395255
stomach9 / 9661993
testis5 / 33044215
thymus2 / 8113124
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus5 / 23287821
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 213177_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.8
Adipocyte6.85
AdrenalCortex8.85
Adrenalgland6.15
Amygdala22.5
Appendix7.65
AtrioventricularNode6.85
BDCA4+_DentriticCells8.2
Bonemarrow7.15
BronchialEpithelialCells7.15
CD105+_Endothelial6.65
CD14+_Monocytes7.7
CD19+_BCells(neg._sel.)7.15
CD33+_Myeloid8.5
CD34+7.85
CD4+_Tcells7.8
CD56+_NKCells8.1
CD71+_EarlyErythroid6.3
CD8+_Tcells7.1
CardiacMyocytes8.95
Caudatenucleus12
Cerebellum6.5
CerebellumPeduncles9
CiliaryGanglion6.65
CingulateCortex9.8
Colorectaladenocarcinoma7.3
DorsalRootGanglion6.45
FetalThyroid6.95
Fetalbrain7.6
Fetalliver5.95
Fetallung5.3
GlobusPallidus9.95
Heart9.55
Hypothalamus8
Kidney6.25
Leukemia_chronicMyelogenousK-5626.5
Leukemia_promyelocytic-HL-606.4
Leukemialymphoblastic(MOLT-4)7.2
Liver9.4
Lung7.35
Lymphnode6.25
Lymphoma_burkitts(Daudi)9.2
Lymphoma_burkitts(Raji)13.55
MedullaOblongata9.05
OccipitalLobe9
OlfactoryBulb5.7
Ovary4.95
Pancreas5.85
PancreaticIslet7.65
ParietalLobe15.85
Pituitary8.6
Placenta6.95
Pons10.85
PrefrontalCortex105.95
Prostate8.15
Salivarygland5.85
SkeletalMuscle10.85
Skin6.4
SmoothMuscle7.9
Spinalcord8.5
SubthalamicNucleus19.65
SuperiorCervicalGanglion9.05
TemporalLobe11.05
Testis6.2
TestisGermCell5.7
TestisIntersitial6.15
TestisLeydigCell7.45
TestisSeminiferousTubule6.35
Thalamus9.05
Thymus5.75
Thyroid8.2
Tongue7.1
Tonsil7.4
Trachea6
TrigeminalGanglion7.85
Uterus5.6
UterusCorpus6.5
WholeBlood7.75
Wholebrain6.2
colon7.25
pineal_day17.36
pineal_night10.86
retina8.95
small_intestine7
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_9924_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.43 ± 0.7
Basal Forebrain5.11 ± 0.64
Basal Part of Pons5.51 ± 0.62
Cerebellar Cortex5.62 ± 0.42
Cerebellar Nuclei4.74 ± 0.81
Claustrum5.82 ± 0.62
Epithalamus4.25 ± 0.68
Frontal Lobe5.38 ± 0.6
Globus Pallidus4.44 ± 0.61
Hypothalamus5.08 ± 0.55
Insula5.11 ± 0.42
Limbic Lobe5.67 ± 0.51
Mesencephalon5.25 ± 0.63
Myelencephalon5.36 ± 0.76
Occipital Lobe5.45 ± 0.59
Parietal Lobe5.46 ± 0.61
Pontine Tegmentum5.11 ± 0.63
Striatum4.71 ± 0.66
Subthalamus4.85 ± 0.2
Temporal Lobe5.34 ± 0.62
Thalamus5.23 ± 0.61
White Matter5.62 ± 0.76
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Mapk8ip3CBCerebellum54.6
80.13
Mapk8ip3CTXCerebral cortex100
100
Mapk8ip3HIPHippocampal region100
100
Mapk8ip3HPFHippocampal formation100
100
Mapk8ip3HYHypothalamus100
100
Mapk8ip3LSXLateral septal complex100
100
Mapk8ip3MBMidbrain100
100
Mapk8ip3MYMedulla99.48
100
Mapk8ip3OLFOlfactory bulb100
100
Mapk8ip3PPons100
100
Mapk8ip3PALPallidum100
100
Mapk8ip3RHPRetrohippocampal region100
100
Mapk8ip3sAMYStriatum-like amygdalar nuclei100
100
Mapk8ip3STRStriatum100
100
Mapk8ip3STRdStriatum dorsal region100
100
Mapk8ip3STRvStriatum ventral region100
100
Mapk8ip3THThalamus100
100
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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