AutismKB 2.0

Annotation Detail for RTF1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:RTF1 ( GTL7,KIAA0252 )
Gene Full Name: Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
Band: 15q15.1
Quick LinksEntrez ID:23168; OMIM: 611633; Uniprot ID:RTF1_HUMAN; ENSEMBL ID: ENSG00000137815; HGNC ID: 28996
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst6 / 6231996
fetus38 / 56401267
neonate1 / 3109732
infant6 / 23620254
juvenile2 / 5555635
adult113 / 193912158
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor3 / 12794234
bladder carcinoma2 / 17475114
breast (mammary gland) tumor10 / 94178106
cervical tumor2 / 3436658
chondrosarcoma10 / 82823120
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor6 / 11936950
germ cell tumor25 / 26384594
glioma3 / 10688328
head and neck tumor5 / 13630236
kidney tumor2 / 6895929
leukemia2 / 9584220
liver tumor4 / 9635941
lung tumor6 / 10312758
lymphoma2 / 7175527
non-neoplasia5 / 9725051
normal194 / 336030757
ovarian tumor3 / 7668239
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS9 / 12568071
prostate cancer3 / 10268029
retinoblastoma1 / 4635621
skin tumor7 / 12494956
soft tissue/muscle tissue tumor12 / 12519195
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland3 / 3319790
ascites2 / 4001549
bladder3 / 29757100
blood2 / 12347816
bone7 / 7165597
bone marrow3 / 4880161
brain46 / 110098941
cervix2 / 4817141
connective tissue8 / 14925553
ear0 / 162120 
embryonic tissue20 / 21572292
esophagus0 / 202090 
eye22 / 211054104
heart4 / 8962644
intestine8 / 23447234
kidney19 / 21177789
larynx0 / 241450 
liver12 / 20774357
lung29 / 33697486
lymph1 / 4427022
lymph node9 / 9161098
mammary gland13 / 15327184
mouth5 / 6705274
muscle13 / 107715120
nerve0 / 157680 
ovary4 / 10205139
pancreas6 / 21481227
parathyroid2 / 2053997
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta5 / 28082517
prostate10 / 18934552
salivary gland1 / 2015549
skin10 / 21057447
spleen1 / 5395218
stomach5 / 9661951
testis26 / 33044278
thymus3 / 8113136
thyroid1 / 4747321
tonsil1 / 1699958
trachea1 / 5241319
umbilical cord1 / 1368073
uterus16 / 23287868
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 212302_at
Cell line Expression level Expression bar
721_B_lymphoblasts14.3
Adipocyte9.4
AdrenalCortex9.5
Adrenalgland7.9
Amygdala9.75
Appendix8.5
AtrioventricularNode7.15
BDCA4+_DentriticCells17.25
Bonemarrow9.1
BronchialEpithelialCells7.7
CD105+_Endothelial19.05
CD14+_Monocytes11.35
CD19+_BCells(neg._sel.)14.45
CD33+_Myeloid16.3
CD34+19.2
CD4+_Tcells12.75
CD56+_NKCells12.45
CD71+_EarlyErythroid11.2
CD8+_Tcells19.3
CardiacMyocytes11.65
Caudatenucleus8.7
Cerebellum8.05
CerebellumPeduncles11.4
CiliaryGanglion6.95
CingulateCortex11.15
Colorectaladenocarcinoma9.45
DorsalRootGanglion7.3
FetalThyroid9.2
Fetalbrain15.5
Fetalliver8.1
Fetallung7.9
GlobusPallidus6.95
Heart11.4
Hypothalamus11.2
Kidney7.55
Leukemia_chronicMyelogenousK-5628.5
Leukemia_promyelocytic-HL-609.35
Leukemialymphoblastic(MOLT-4)16.15
Liver11.85
Lung7.4
Lymphnode8.8
Lymphoma_burkitts(Daudi)11.95
Lymphoma_burkitts(Raji)11.55
MedullaOblongata8.65
OccipitalLobe9.55
OlfactoryBulb7.35
Ovary6.2
Pancreas7.6
PancreaticIslet9.95
ParietalLobe9.85
Pituitary11.5
Placenta9.7
Pons8.9
PrefrontalCortex11.8
Prostate10.05
Salivarygland7.8
SkeletalMuscle10.4
Skin7.1
SmoothMuscle10.75
Spinalcord10
SubthalamicNucleus9.9
SuperiorCervicalGanglion10.3
TemporalLobe8.95
Testis8.25
TestisGermCell9.9
TestisIntersitial8.4
TestisLeydigCell9.35
TestisSeminiferousTubule10.25
Thalamus9.6
Thymus7.6
Thyroid11.85
Tongue9.35
Tonsil9.7
Trachea7.85
TrigeminalGanglion9.1
Uterus7.65
UterusCorpus6.4
WholeBlood10.65
Wholebrain7.9
colon9.1
pineal_day16.08
pineal_night12.7
retina11.45
small_intestine7.6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P77321
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.24 ± 0.28
Basal Forebrain6.73 ± 0.13
Basal Part of Pons6.83 ± 0.36
Cerebellar Cortex6.87 ± 0.22
Cerebellar Nuclei6.51 ± 0.3
Claustrum7.1 ± 0.41
Epithalamus6.7 ± 0.27
Frontal Lobe6.84 ± 0.3
Globus Pallidus6.25 ± 0.3
Hypothalamus6.8 ± 0.3
Insula7.01 ± 0.28
Limbic Lobe7.23 ± 0.3
Mesencephalon6.91 ± 0.35
Myelencephalon6.93 ± 0.3
Occipital Lobe7.34 ± 0.39
Parietal Lobe6.97 ± 0.29
Pontine Tegmentum6.92 ± 0.33
Striatum7.12 ± 0.26
Subthalamus6.67 ± 0.21
Temporal Lobe6.96 ± 0.24
Thalamus6.88 ± 0.28
White Matter6.22 ± 0.35
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Rtf1CBCerebellum32.87
40.24
Rtf1CTXCerebral cortex100
100
Rtf1HIPHippocampal region84.74
100
Rtf1HPFHippocampal formation93.72
100
Rtf1HYHypothalamus33.28
29.59
Rtf1LSXLateral septal complex58.84
55.11
Rtf1MBMidbrain47.68
45.35
Rtf1MYMedulla46.55
54.04
Rtf1OLFOlfactory bulb74.43
73.47
Rtf1PPons34.83
39.31
Rtf1PALPallidum28.89
28.45
Rtf1RHPRetrohippocampal region100
100
Rtf1sAMYStriatum-like amygdalar nuclei68.15
59.81
Rtf1STRStriatum66.18
54.02
Rtf1STRdStriatum dorsal region71.33
57.74
Rtf1STRvStriatum ventral region50.31
39.89
Rtf1THThalamus61.86
57.44
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00006824 27 597 623 RQCKPTIVSNSRDPAVQAAILAQLNAK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved