AutismKB 2.0

Annotation Detail for DIP2A


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Basic Information Top
Gene Symbol:DIP2A ( C21orf106,DIP2 )
Gene Full Name: DIP2 disco-interacting protein 2 homolog A (Drosophila)
Band: 21q22.3
Quick LinksEntrez ID:23181; OMIM: 607711; Uniprot ID:DIP2A_HUMAN; ENSEMBL ID: ENSG00000160305; HGNC ID: 17217
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst3 / 6231948
fetus15 / 56401226
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult90 / 193912146
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor5 / 11424643
esophageal tumor0 / 172900 
gastrointestinal tumor10 / 11936983
germ cell tumor6 / 26384522
glioma2 / 10688318
head and neck tumor6 / 13630244
kidney tumor3 / 6895943
leukemia4 / 9584241
liver tumor2 / 9635920
lung tumor1 / 1031279
lymphoma4 / 7175555
non-neoplasia3 / 9725030
normal119 / 336030735
ovarian tumor1 / 7668213
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer3 / 10268029
retinoblastoma2 / 4635643
skin tumor1 / 1249498
soft tissue/muscle tissue tumor12 / 12519195
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites1 / 4001524
bladder1 / 2975733
blood3 / 12347824
bone0 / 716550 
bone marrow0 / 488010 
brain30 / 110098927
cervix0 / 481710 
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue13 / 21572260
esophagus0 / 202090 
eye15 / 21105471
heart3 / 8962633
intestine11 / 23447246
kidney6 / 21177728
larynx0 / 241450 
liver4 / 20774319
lung15 / 33697444
lymph0 / 442700 
lymph node1 / 9161010
mammary gland6 / 15327139
mouth2 / 6705229
muscle4 / 10771537
nerve1 / 1576863
ovary1 / 1020519
pancreas9 / 21481241
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta12 / 28082542
prostate11 / 18934558
salivary gland0 / 201550 
skin5 / 21057423
spleen1 / 5395218
stomach11 / 96619113
testis9 / 33044227
thymus3 / 8113136
thyroid4 / 4747384
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus10 / 23287842
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P68752
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.03 ± 0.68
Basal Forebrain4.03 ± 0.56
Basal Part of Pons4.29 ± 0.45
Cerebellar Cortex4.44 ± 0.46
Cerebellar Nuclei4.36 ± 0.65
Claustrum3.73 ± 0.66
Epithalamus4.15 ± 0.5
Frontal Lobe4.13 ± 0.52
Globus Pallidus4.32 ± 0.27
Hypothalamus3.96 ± 0.55
Insula4.08 ± 0.33
Limbic Lobe4.06 ± 0.54
Mesencephalon4.27 ± 0.65
Myelencephalon4.15 ± 0.58
Occipital Lobe4.58 ± 0.56
Parietal Lobe4.14 ± 0.58
Pontine Tegmentum4.12 ± 0.53
Striatum4.09 ± 0.72
Subthalamus5.4 ± 0.94
Temporal Lobe4.04 ± 0.53
Thalamus4.07 ± 0.57
White Matter5.63 ± 0.1
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Dip2aCBCerebellum71.92
62.55
Dip2aCTXCerebral cortex87.47
48.51
Dip2aHIPHippocampal region58.37
37.54
Dip2aHPFHippocampal formation86.27
54.82
Dip2aHYHypothalamus74.19
47.64
Dip2aLSXLateral septal complex52.11
31.51
Dip2aMBMidbrain84.2
57.69
Dip2aMYMedulla100
82.52
Dip2aOLFOlfactory bulb87.68
45.59
Dip2aPPons100
85.07
Dip2aPALPallidum82.25
58.6
Dip2aRHPRetrohippocampal region100
80
Dip2asAMYStriatum-like amygdalar nuclei67.27
37.24
Dip2aSTRStriatum48.09
29.37
Dip2aSTRdStriatum dorsal region48.66
30.66
Dip2aSTRvStriatum ventral region34.68
20.17
Dip2aTHThalamus84.46
58.66
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00025588 14 1007 1020 GTVTSTATCVQLHK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018