AutismKB 2.0

Annotation Detail for KANK1


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Basic Information Top
Gene Symbol:KANK1 ( ANKRD15,DKFZp451G231,KANK,KIAA0172,MGC43128 )
Gene Full Name: KN motif and ankyrin repeat domains 1
Band: 9p24.3
Quick LinksEntrez ID:23189; OMIM: 607704; Uniprot ID:KANK1_HUMAN; ENSEMBL ID: ENSG00000107104; HGNC ID: 19309
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst4 / 6231964
fetus29 / 56401251
neonate4 / 31097128
infant0 / 236200 
juvenile3 / 5555653
adult112 / 193912157
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma3 / 8282336
colorectal tumor4 / 11424635
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor10 / 26384537
glioma6 / 10688356
head and neck tumor22 / 136302161
kidney tumor0 / 689590 
leukemia4 / 9584241
liver tumor5 / 9635951
lung tumor3 / 10312729
lymphoma0 / 717550 
non-neoplasia5 / 9725051
normal245 / 336030772
ovarian tumor4 / 7668252
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer0 / 1026800 
retinoblastoma1 / 4635621
skin tumor17 / 124949136
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue3 / 13106228
adrenal gland0 / 331970 
ascites2 / 4001549
bladder1 / 2975733
blood2 / 12347816
bone2 / 7165527
bone marrow2 / 4880140
brain82 / 110098974
cervix0 / 481710 
connective tissue4 / 14925526
ear1 / 1621261
embryonic tissue12 / 21572255
esophagus1 / 2020949
eye7 / 21105433
heart5 / 8962655
intestine9 / 23447238
kidney13 / 21177761
larynx3 / 24145124
liver6 / 20774328
lung14 / 33697441
lymph0 / 442700 
lymph node6 / 9161065
mammary gland2 / 15327113
mouth12 / 67052178
muscle17 / 107715157
nerve2 / 15768126
ovary5 / 10205148
pancreas8 / 21481237
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta17 / 28082560
prostate9 / 18934547
salivary gland0 / 201550 
skin23 / 210574109
spleen0 / 539520 
stomach1 / 9661910
testis25 / 33044275
thymus1 / 8113112
thyroid10 / 47473210
tonsil1 / 1699958
trachea8 / 52413152
umbilical cord3 / 13680219
uterus12 / 23287851
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 213005_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts18.4
Adipocyte97.7
AdrenalCortex6.05
Adrenalgland5.5
Amygdala120.8
Appendix15.45
AtrioventricularNode5.4
BDCA4+_DentriticCells37.65
Bonemarrow4.9
BronchialEpithelialCells29.45
CD105+_Endothelial14.8
CD14+_Monocytes4.35
CD19+_BCells(neg._sel.)5.1
CD33+_Myeloid5.95
CD34+54.9
CD4+_Tcells5.9
CD56+_NKCells4.8
CD71+_EarlyErythroid4.55
CD8+_Tcells4.2
CardiacMyocytes6.45
Caudatenucleus31.55
Cerebellum27.45
CerebellumPeduncles14.9
CiliaryGanglion5.55
CingulateCortex14.9
Colorectaladenocarcinoma4.3
DorsalRootGanglion7.45
FetalThyroid26.3
Fetalbrain6.1
Fetalliver57.35
Fetallung20.4
GlobusPallidus5.2
Heart48.7
Hypothalamus92.25
Kidney41.45
Leukemia_chronicMyelogenousK-5623.95
Leukemia_promyelocytic-HL-6012.55
Leukemialymphoblastic(MOLT-4)5.1
Liver55.65
Lung44.65
Lymphnode7.25
Lymphoma_burkitts(Daudi)74.5
Lymphoma_burkitts(Raji)9.95
MedullaOblongata12.45
OccipitalLobe23
OlfactoryBulb106.2
Ovary3.25
Pancreas10.75
PancreaticIslet20.7
ParietalLobe11.8
Pituitary32.4
Placenta105.65
Pons7.9
PrefrontalCortex142.4
Prostate157.2
Salivarygland11.85
SkeletalMuscle7.1
Skin13.6
SmoothMuscle7.4
Spinalcord111.25
SubthalamicNucleus6.65
SuperiorCervicalGanglion6.6
TemporalLobe5.9
Testis23.45
TestisGermCell37.8
TestisIntersitial9.85
TestisLeydigCell7.8
TestisSeminiferousTubule11.9
Thalamus20.35
Thymus13
Thyroid87.2
Tongue42.5
Tonsil9.5
Trachea28.55
TrigeminalGanglion6.7
Uterus338.55
UterusCorpus11.7
WholeBlood4.4
Wholebrain41.75
colon68.55
pineal_day16.64
pineal_night11.06
retina103.875
small_intestine58.7
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_32_P64570
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.18 ± 0.29
Basal Forebrain8.48 ± 0.3
Basal Part of Pons7.58 ± 0.25
Cerebellar Cortex8.25 ± 0.16
Cerebellar Nuclei8.3 ± 0.26
Claustrum8.13 ± 0.3
Epithalamus8.42 ± 0.14
Frontal Lobe7.89 ± 0.45
Globus Pallidus9.21 ± 0.41
Hypothalamus7.94 ± 0.38
Insula7.81 ± 0.28
Limbic Lobe7.87 ± 0.64
Mesencephalon8.29 ± 0.31
Myelencephalon8.19 ± 0.4
Occipital Lobe8.17 ± 0.49
Parietal Lobe7.9 ± 0.51
Pontine Tegmentum8.15 ± 0.4
Striatum8.41 ± 0.63
Subthalamus8.14 ± 0.36
Temporal Lobe7.93 ± 0.34
Thalamus8.33 ± 0.24
White Matter9.55 ± 0.41
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ankrd15CBCerebellum5.01
4.69
Ankrd15CTXCerebral cortex3.88
3
Ankrd15HIPHippocampal region2.22
2.18
Ankrd15HPFHippocampal formation2.37
2.16
Ankrd15HYHypothalamus3.53
2.89
Ankrd15LSXLateral septal complex3.11
2.66
Ankrd15MBMidbrain3.94
3.65
Ankrd15MYMedulla9.53
9.03
Ankrd15OLFOlfactory bulb7.55
6.81
Ankrd15PPons5.33
4.93
Ankrd15PALPallidum4.11
3.41
Ankrd15RHPRetrohippocampal region2.6
2.13
Ankrd15sAMYStriatum-like amygdalar nuclei1.64
1.51
Ankrd15STRStriatum3.25
2.65
Ankrd15STRdStriatum dorsal region3.58
3.02
Ankrd15STRvStriatum ventral region2.81
1.93
Ankrd15THThalamus4.09
3.46
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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