AutismKB 2.0

Annotation Detail for FLOT2


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Basic Information Top
Gene Symbol:FLOT2 ( ECS-1,ECS1,ESA,ESA1,M17S1 )
Gene Full Name: flotillin 2
Band: 17q11.2
Quick LinksEntrez ID:2319; OMIM: 131560; Uniprot ID:FLOT2_HUMAN; ENSEMBL ID: ENSG00000132589; HGNC ID: 3758
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst6 / 6231996
fetus24 / 56401242
neonate0 / 310970 
infant2 / 2362084
juvenile0 / 555560 
adult241 / 1939121124
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor5 / 9417853
cervical tumor9 / 34366261
chondrosarcoma11 / 82823132
colorectal tumor20 / 114246175
esophageal tumor0 / 172900 
gastrointestinal tumor11 / 11936992
germ cell tumor21 / 26384579
glioma10 / 10688393
head and neck tumor18 / 136302132
kidney tumor12 / 68959174
leukemia24 / 95842250
liver tumor9 / 9635993
lung tumor18 / 103127174
lymphoma17 / 71755236
non-neoplasia3 / 9725030
normal209 / 336030762
ovarian tumor7 / 7668291
pancreatic tumor12 / 104616114
primitive neuroectodermal tumor of the CNS23 / 125680183
prostate cancer40 / 102680389
retinoblastoma3 / 4635664
skin tumor10 / 12494980
soft tissue/muscle tissue tumor8 / 12519163
uterine tumor10 / 90257110
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites9 / 40015224
bladder2 / 2975767
blood27 / 123478218
bone3 / 7165541
bone marrow0 / 488010 
brain48 / 110098943
cervix15 / 48171311
connective tissue9 / 14925560
ear0 / 162120 
embryonic tissue19 / 21572288
esophagus0 / 202090 
eye23 / 211054108
heart8 / 8962689
intestine27 / 234472115
kidney17 / 21177780
larynx12 / 24145496
liver14 / 20774367
lung40 / 336974118
lymph11 / 44270248
lymph node10 / 91610109
mammary gland10 / 15327165
mouth2 / 6705229
muscle1 / 1077159
nerve0 / 157680 
ovary10 / 10205197
pancreas15 / 21481269
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta29 / 280825103
prostate42 / 189345221
salivary gland2 / 2015599
skin21 / 21057499
spleen3 / 5395255
stomach5 / 9661951
testis5 / 33044215
thymus2 / 8113124
thyroid2 / 4747342
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus26 / 232878111
vascular4 / 5178077
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 201350_at
Cell line Expression level Expression bar
721_B_lymphoblasts83.2
Adipocyte47
AdrenalCortex49.5
Adrenalgland55.2
Amygdala76.45
Appendix45.95
AtrioventricularNode47.95
BDCA4+_DentriticCells195.6
Bonemarrow194.5
BronchialEpithelialCells86.45
CD105+_Endothelial103.45
CD14+_Monocytes292.55
CD19+_BCells(neg._sel.)371.9
CD33+_Myeloid277
CD34+125.75
CD4+_Tcells136.35
CD56+_NKCells339.65
CD71+_EarlyErythroid180.55
CD8+_Tcells149
CardiacMyocytes65.85
Caudatenucleus59.4
Cerebellum62.9
CerebellumPeduncles67.75
CiliaryGanglion33.25
CingulateCortex75.8
Colorectaladenocarcinoma70.5
DorsalRootGanglion49.4
FetalThyroid64.5
Fetalbrain82.9
Fetalliver83.75
Fetallung65.8
GlobusPallidus38
Heart211.1
Hypothalamus61.3
Kidney78.65
Leukemia_chronicMyelogenousK-56290.55
Leukemia_promyelocytic-HL-6056.9
Leukemialymphoblastic(MOLT-4)45.95
Liver139.65
Lung167.75
Lymphnode98.95
Lymphoma_burkitts(Daudi)94.5
Lymphoma_burkitts(Raji)105.25
MedullaOblongata58.75
OccipitalLobe71.65
OlfactoryBulb51.65
Ovary43.35
Pancreas29.3
PancreaticIslet100
ParietalLobe68.8
Pituitary63.8
Placenta128.85
Pons45.8
PrefrontalCortex90.65
Prostate176.65
Salivarygland41.6
SkeletalMuscle56.6
Skin35.65
SmoothMuscle68.4
Spinalcord74.8
SubthalamicNucleus61.55
SuperiorCervicalGanglion52.85
TemporalLobe74.9
Testis49.9
TestisGermCell23.4
TestisIntersitial34.8
TestisLeydigCell54.6
TestisSeminiferousTubule40.95
Thalamus63
Thymus98.35
Thyroid70.25
Tongue59.9
Tonsil88.45
Trachea55.7
TrigeminalGanglion55.6
Uterus34
UterusCorpus43.1
WholeBlood939.75
Wholebrain103.05
colon48.1
pineal_day68.9
pineal_night65.48
retina85.725
small_intestine33.8
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P253818
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.52 ± 0.44
Basal Forebrain3.9 ± 0.52
Basal Part of Pons4.55 ± 0.6
Cerebellar Cortex3.66 ± 0.54
Cerebellar Nuclei3.27 ± 0.68
Claustrum5.03 ± 0.61
Epithalamus3.71 ± 0.65
Frontal Lobe3.97 ± 0.57
Globus Pallidus3.57 ± 0.78
Hypothalamus3.69 ± 0.6
Insula3.57 ± 0.98
Limbic Lobe4.34 ± 0.71
Mesencephalon3.92 ± 0.67
Myelencephalon4.08 ± 0.62
Occipital Lobe4.59 ± 0.59
Parietal Lobe4.03 ± 0.56
Pontine Tegmentum3.9 ± 0.59
Striatum3.99 ± 0.69
Subthalamus3.8 ± 0.5
Temporal Lobe4.11 ± 0.54
Thalamus4.11 ± 0.68
White Matter2.86 ± 0.58
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Flot2CBCerebellum29.39
33.55
Flot2CTXCerebral cortex100
100
Flot2HIPHippocampal region82.83
100
Flot2HPFHippocampal formation93.45
100
Flot2HYHypothalamus94.9
95.07
Flot2LSXLateral septal complex72.85
49.39
Flot2MBMidbrain94.18
98.27
Flot2MYMedulla81.68
99.03
Flot2OLFOlfactory bulb91.37
92.84
Flot2PPons86.32
96.51
Flot2PALPallidum77.57
70.54
Flot2RHPRetrohippocampal region100
100
Flot2sAMYStriatum-like amygdalar nuclei99.26
94.2
Flot2STRStriatum72.18
49.87
Flot2STRdStriatum dorsal region67.03
46.07
Flot2STRvStriatum ventral region61.65
38
Flot2THThalamus88.06
77.82
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00002143 13 82 94 ELLAVACEQFLGK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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