AutismKB 2.0

Annotation Detail for MDN1


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Basic Information Top
Gene Symbol:MDN1 ( DKFZp686H16106,FLJ23395,FLJ25587,FLJ42031,FLJ43191,KIAA0301 )
Gene Full Name: MDN1, midasin homolog (yeast)
Band: 6q15
Quick LinksEntrez ID:23195; OMIM: NA; Uniprot ID:MDN1_HUMAN; ENSEMBL ID: ENSG00000112159; HGNC ID: 18302
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst8 / 62319128
fetus31 / 56401254
neonate1 / 3109732
infant1 / 2362042
juvenile1 / 5555617
adult107 / 193912155
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma2 / 17475114
breast (mammary gland) tumor12 / 94178127
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor8 / 11424670
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor22 / 26384583
glioma3 / 10688328
head and neck tumor8 / 13630258
kidney tumor2 / 6895929
leukemia3 / 9584231
liver tumor2 / 9635920
lung tumor5 / 10312748
lymphoma4 / 7175555
non-neoplasia1 / 9725010
normal165 / 336030749
ovarian tumor2 / 7668226
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer1 / 1026809
retinoblastoma8 / 46356172
skin tumor6 / 12494948
soft tissue/muscle tissue tumor5 / 12519139
uterine tumor8 / 9025788
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood6 / 12347848
bone2 / 7165527
bone marrow0 / 488010 
brain60 / 110098954
cervix0 / 481710 
connective tissue0 / 1492550 
ear2 / 16212123
embryonic tissue15 / 21572269
esophagus0 / 202090 
eye11 / 21105452
heart5 / 8962655
intestine13 / 23447255
kidney8 / 21177737
larynx2 / 2414582
liver12 / 20774357
lung18 / 33697453
lymph4 / 4427090
lymph node3 / 9161032
mammary gland18 / 153271117
mouth1 / 6705214
muscle6 / 10771555
nerve1 / 1576863
ovary3 / 10205129
pancreas8 / 21481237
parathyroid1 / 2053948
pharynx2 / 4132848
pituitary gland2 / 16585120
placenta0 / 2808250 
prostate3 / 18934515
salivary gland0 / 201550 
skin12 / 21057456
spleen3 / 5395255
stomach4 / 9661941
testis16 / 33044248
thymus3 / 8113136
thyroid6 / 47473126
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus16 / 23287868
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 212693_at
Cell line Expression level Expression bar
721_B_lymphoblasts27.45
Adipocyte4.2
AdrenalCortex4.3
Adrenalgland3.45
Amygdala5.6
Appendix4.25
AtrioventricularNode3.15
BDCA4+_DentriticCells18.7
Bonemarrow4.15
BronchialEpithelialCells3.8
CD105+_Endothelial6.45
CD14+_Monocytes4.55
CD19+_BCells(neg._sel.)5.25
CD33+_Myeloid5.6
CD34+34.1
CD4+_Tcells47.85
CD56+_NKCells5.4
CD71+_EarlyErythroid4
CD8+_Tcells35.45
CardiacMyocytes5.2
Caudatenucleus4
Cerebellum3.45
CerebellumPeduncles4.85
CiliaryGanglion2.9
CingulateCortex4.4
Colorectaladenocarcinoma4.3
DorsalRootGanglion3.2
FetalThyroid4.45
Fetalbrain5.35
Fetalliver4.6
Fetallung4.3
GlobusPallidus3.15
Heart5.35
Hypothalamus11.85
Kidney3.4
Leukemia_chronicMyelogenousK-56220.55
Leukemia_promyelocytic-HL-6022.35
Leukemialymphoblastic(MOLT-4)3.7
Liver5.5
Lung4.8
Lymphnode3.8
Lymphoma_burkitts(Daudi)10.65
Lymphoma_burkitts(Raji)10.95
MedullaOblongata4
OccipitalLobe4.95
OlfactoryBulb3.75
Ovary2.8
Pancreas3.4
PancreaticIslet4.55
ParietalLobe4.5
Pituitary5.1
Placenta4.35
Pons4
PrefrontalCortex12.1
Prostate5.1
Salivarygland3.4
SkeletalMuscle4.55
Skin3.2
SmoothMuscle4.55
Spinalcord4.65
SubthalamicNucleus3.85
SuperiorCervicalGanglion4.75
TemporalLobe3.85
Testis3.85
TestisGermCell10.7
TestisIntersitial3.7
TestisLeydigCell4.25
TestisSeminiferousTubule3.8
Thalamus4.45
Thymus3.5
Thyroid6.3
Tongue4.1
Tonsil4.45
Trachea3.4
TrigeminalGanglion4.15
Uterus3.65
UterusCorpus3.75
WholeBlood4.7
Wholebrain3.7
colon4.15
pineal_day6.14
pineal_night5.86
retina5.475
small_intestine3.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P365060
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.17 ± 0.55
Basal Forebrain5.45 ± 0.42
Basal Part of Pons5.65 ± 0.34
Cerebellar Cortex5.4 ± 0.42
Cerebellar Nuclei5.56 ± 0.36
Claustrum5.01 ± 0.67
Epithalamus5.34 ± 0.37
Frontal Lobe5.24 ± 0.4
Globus Pallidus5.96 ± 0.37
Hypothalamus5.51 ± 0.34
Insula5.26 ± 0.28
Limbic Lobe5.38 ± 0.49
Mesencephalon5.45 ± 0.45
Myelencephalon5.33 ± 0.52
Occipital Lobe5.79 ± 0.35
Parietal Lobe5.48 ± 0.43
Pontine Tegmentum5.34 ± 0.48
Striatum5.63 ± 0.33
Subthalamus5.5 ± 0.54
Temporal Lobe5.34 ± 0.39
Thalamus5.35 ± 0.49
White Matter6.76 ± 0.34
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
MDN1_HUMAN_1 14 1 14 MEHFLLEVAAAPLR PRIDE
MDN1_HUMAN_2288 14 2288 2301 LFLSMDPVHGDISR PRIDE
MDN1_HUMAN_4020 35 4020 4054 ALRETLLAQPAAGQATIPEWCQGAAPSGLEGELLR PRIDE
MDN1_HUMAN_5100 9 5100 5108 KPGQADNER PRIDE
PAp00038917 23 267 289 VTAVCGVVLPGQLPAPGELGGNR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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