AutismKB 2.0

Annotation Detail for FAF2


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Basic Information Top
Gene Symbol:FAF2 ( ETEA,KIAA0887,UBXD8,UBXN3B )
Gene Full Name: Fas associated factor family member 2
Band: 5q35.2
Quick LinksEntrez ID:23197; OMIM: NA; Uniprot ID:FAF2_HUMAN; ENSEMBL ID: ENSG00000113194; HGNC ID: 24666
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body9 / 70761127
blastocyst6 / 6231996
fetus57 / 564012101
neonate1 / 3109732
infant0 / 236200 
juvenile4 / 5555671
adult148 / 193912176
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor12 / 94178127
cervical tumor2 / 3436658
chondrosarcoma9 / 82823108
colorectal tumor15 / 114246131
esophageal tumor2 / 17290115
gastrointestinal tumor19 / 119369159
germ cell tumor18 / 26384568
glioma3 / 10688328
head and neck tumor9 / 13630266
kidney tumor2 / 6895929
leukemia2 / 9584220
liver tumor3 / 9635931
lung tumor6 / 10312758
lymphoma3 / 7175541
non-neoplasia6 / 9725061
normal237 / 336030770
ovarian tumor7 / 7668291
pancreatic tumor26 / 104616248
primitive neuroectodermal tumor of the CNS6 / 12568047
prostate cancer11 / 102680107
retinoblastoma1 / 4635621
skin tumor7 / 12494956
soft tissue/muscle tissue tumor8 / 12519163
uterine tumor10 / 90257110
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland2 / 3319760
ascites9 / 40015224
bladder0 / 297570 
blood6 / 12347848
bone7 / 7165597
bone marrow2 / 4880140
brain37 / 110098933
cervix2 / 4817141
connective tissue8 / 14925553
ear4 / 16212246
embryonic tissue22 / 215722101
esophagus2 / 2020998
eye19 / 21105490
heart17 / 89626189
intestine35 / 234472149
kidney15 / 21177770
larynx1 / 2414541
liver9 / 20774343
lung29 / 33697486
lymph1 / 4427022
lymph node8 / 9161087
mammary gland21 / 153271137
mouth4 / 6705259
muscle11 / 107715102
nerve2 / 15768126
ovary8 / 10205178
pancreas36 / 214812167
parathyroid1 / 2053948
pharynx3 / 4132872
pituitary gland2 / 16585120
placenta11 / 28082539
prostate12 / 18934563
salivary gland1 / 2015549
skin16 / 21057475
spleen1 / 5395218
stomach6 / 9661962
testis22 / 33044266
thymus3 / 8113136
thyroid2 / 4747342
tonsil0 / 169990 
trachea4 / 5241376
umbilical cord0 / 136800 
uterus17 / 23287872
vascular1 / 5178019
Microarray in BioGPS Top
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  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 212108_at
Cell line Expression level Expression bar
721_B_lymphoblasts74.75
Adipocyte38.2
AdrenalCortex41.85
Adrenalgland33.65
Amygdala37.2
Appendix36
AtrioventricularNode26.9
BDCA4+_DentriticCells40.5
Bonemarrow34.95
BronchialEpithelialCells109.25
CD105+_Endothelial45.7
CD14+_Monocytes27.1
CD19+_BCells(neg._sel.)21.25
CD33+_Myeloid56.7
CD34+67.65
CD4+_Tcells37.9
CD56+_NKCells45.45
CD71+_EarlyErythroid31.25
CD8+_Tcells35.25
CardiacMyocytes51.15
Caudatenucleus32.2
Cerebellum29.05
CerebellumPeduncles42.55
CiliaryGanglion23.65
CingulateCortex32.3
Colorectaladenocarcinoma44
DorsalRootGanglion24.65
FetalThyroid37.7
Fetalbrain36.3
Fetalliver31.55
Fetallung28.65
GlobusPallidus24
Heart40.5
Hypothalamus39.6
Kidney27.85
Leukemia_chronicMyelogenousK-56232.8
Leukemia_promyelocytic-HL-6027.3
Leukemialymphoblastic(MOLT-4)36.5
Liver46.2
Lung30.85
Lymphnode31.35
Lymphoma_burkitts(Daudi)46
Lymphoma_burkitts(Raji)44.05
MedullaOblongata32.95
OccipitalLobe33.7
OlfactoryBulb29.05
Ovary20.15
Pancreas29.5
PancreaticIslet38.75
ParietalLobe37.55
Pituitary45.85
Placenta62.1
Pons34.1
PrefrontalCortex45.15
Prostate43.6
Salivarygland28.45
SkeletalMuscle45.5
Skin27.15
SmoothMuscle75.05
Spinalcord35.9
SubthalamicNucleus30.45
SuperiorCervicalGanglion41.1
TemporalLobe32.85
Testis51.45
TestisGermCell57.95
TestisIntersitial33.65
TestisLeydigCell35.8
TestisSeminiferousTubule45.45
Thalamus36.45
Thymus32.3
Thyroid43
Tongue34.7
Tonsil45.9
Trachea30.15
TrigeminalGanglion35.1
Uterus28.9
UterusCorpus33.25
WholeBlood37.85
Wholebrain29.55
colon36.2
pineal_day69.92
pineal_night63.3
retina43.825
small_intestine35.05
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P156109
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.1 ± 0.3
Basal Forebrain7.06 ± 0.17
Basal Part of Pons7.12 ± 0.19
Cerebellar Cortex7.26 ± 0.28
Cerebellar Nuclei6.97 ± 0.25
Claustrum6.85 ± 0.43
Epithalamus7.1 ± 0.25
Frontal Lobe7.04 ± 0.27
Globus Pallidus6.89 ± 0.23
Hypothalamus6.97 ± 0.33
Insula7.08 ± 0.16
Limbic Lobe7.13 ± 0.31
Mesencephalon7.04 ± 0.42
Myelencephalon7.03 ± 0.3
Occipital Lobe7.18 ± 0.27
Parietal Lobe7.05 ± 0.25
Pontine Tegmentum7.03 ± 0.31
Striatum7 ± 0.32
Subthalamus7.19 ± 0.23
Temporal Lobe7.06 ± 0.32
Thalamus7.08 ± 0.2
White Matter7.19 ± 0.18
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ubxd8CBCerebellum53.9
79.33
Ubxd8CTXCerebral cortex96.51
78.48
Ubxd8HIPHippocampal region50.38
81.46
Ubxd8HPFHippocampal formation54.54
67.41
Ubxd8HYHypothalamus46.02
38.84
Ubxd8LSXLateral septal complex74.92
54.68
Ubxd8MBMidbrain45.96
42.16
Ubxd8MYMedulla45.13
50.39
Ubxd8OLFOlfactory bulb72.19
70.52
Ubxd8PPons44.25
48.07
Ubxd8PALPallidum36.69
33.31
Ubxd8RHPRetrohippocampal region62.9
52.55
Ubxd8sAMYStriatum-like amygdalar nuclei36.82
27.62
Ubxd8STRStriatum46.57
34.14
Ubxd8STRdStriatum dorsal region45.03
32.99
Ubxd8STRvStriatum ventral region47.68
35.16
Ubxd8THThalamus54.19
45.39
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00000408 19 150 168 AHPVFYQGTYSQALNDAKR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018