AutismKB 2.0

Annotation Detail for FLT1


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Basic Information Top
Gene Symbol:FLT1 ( FLT,VEGFR1 )
Gene Full Name: fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
Band: 13q12.3
Quick LinksEntrez ID:2321; OMIM: 165070; Uniprot ID:VGFR1_HUMAN; ENSEMBL ID: ENSG00000102755; HGNC ID: 3763
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst2 / 6231932
fetus33 / 56401258
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult203 / 1939121104
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma7 / 8282384
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor4 / 26384515
glioma1 / 1068839
head and neck tumor6 / 13630244
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor2 / 9635920
lung tumor0 / 1031270 
lymphoma1 / 7175513
non-neoplasia1 / 9725010
normal298 / 336030788
ovarian tumor0 / 766820 
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor2 / 12494916
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor6 / 9025766
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood2 / 12347816
bone1 / 7165513
bone marrow0 / 488010 
brain23 / 110098920
cervix0 / 481710 
connective tissue10 / 14925566
ear0 / 162120 
embryonic tissue6 / 21572227
esophagus0 / 202090 
eye20 / 21105494
heart2 / 8962622
intestine2 / 2344728
kidney13 / 21177761
larynx0 / 241450 
liver2 / 2077439
lung8 / 33697423
lymph0 / 442700 
lymph node0 / 916100 
mammary gland2 / 15327113
mouth0 / 670520 
muscle3 / 10771527
nerve2 / 15768126
ovary2 / 10205119
pancreas12 / 21481255
parathyroid4 / 20539194
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta131 / 280825466
prostate5 / 18934526
salivary gland0 / 201550 
skin2 / 2105749
spleen1 / 5395218
stomach2 / 9661920
testis19 / 33044257
thymus1 / 8113112
thyroid6 / 47473126
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus22 / 23287894
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 222033_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.35
Adipocyte6.45
AdrenalCortex13.55
Adrenalgland7.95
Amygdala7.25
Appendix7.2
AtrioventricularNode6
BDCA4+_DentriticCells6.45
Bonemarrow6.55
BronchialEpithelialCells6
CD105+_Endothelial6.45
CD14+_Monocytes6.75
CD19+_BCells(neg._sel.)6.45
CD33+_Myeloid7.9
CD34+7.75
CD4+_Tcells6.45
CD56+_NKCells7.05
CD71+_EarlyErythroid6.15
CD8+_Tcells5.65
CardiacMyocytes8.8
Caudatenucleus6.4
Cerebellum5.25
CerebellumPeduncles8.95
CiliaryGanglion5.95
CingulateCortex14.6
Colorectaladenocarcinoma6.3
DorsalRootGanglion8.75
FetalThyroid7.65
Fetalbrain6.2
Fetalliver5.7
Fetallung8.4
GlobusPallidus7.85
Heart9.7
Hypothalamus11.1
Kidney7.95
Leukemia_chronicMyelogenousK-5625.65
Leukemia_promyelocytic-HL-605.6
Leukemialymphoblastic(MOLT-4)4.85
Liver8.8
Lung6.9
Lymphnode5.9
Lymphoma_burkitts(Daudi)8.4
Lymphoma_burkitts(Raji)9.35
MedullaOblongata7.15
OccipitalLobe6.55
OlfactoryBulb5.25
Ovary4.75
Pancreas6.65
PancreaticIslet7.55
ParietalLobe8.2
Pituitary7.75
Placenta8.9
Pons6.7
PrefrontalCortex17.5
Prostate7.15
Salivarygland5.4
SkeletalMuscle12.4
Skin5.55
SmoothMuscle7.05
Spinalcord7.95
SubthalamicNucleus7.8
SuperiorCervicalGanglion8.65
TemporalLobe6.65
Testis5.55
TestisGermCell5.6
TestisIntersitial5.5
TestisLeydigCell9.05
TestisSeminiferousTubule5.7
Thalamus9.45
Thymus4.8
Thyroid24.15
Tongue6.85
Tonsil6.4
Trachea5.4
TrigeminalGanglion7.2
Uterus6.6
UterusCorpus7.45
WholeBlood6.6
Wholebrain5.05
colon6.6
pineal_day8
pineal_night7.8
retina9.425
small_intestine6.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P246125
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.42 ± 0.66
Basal Forebrain4.5 ± 0.47
Basal Part of Pons4.4 ± 0.42
Cerebellar Cortex4.26 ± 0.44
Cerebellar Nuclei6.04 ± 0.35
Claustrum4.68 ± 0.7
Epithalamus4.5 ± 0.89
Frontal Lobe4.77 ± 0.65
Globus Pallidus6.18 ± 0.31
Hypothalamus4.58 ± 0.64
Insula4.61 ± 0.44
Limbic Lobe4.7 ± 0.66
Mesencephalon5.15 ± 0.64
Myelencephalon4.93 ± 0.71
Occipital Lobe5.21 ± 0.85
Parietal Lobe4.73 ± 0.61
Pontine Tegmentum4.98 ± 0.81
Striatum5.67 ± 0.56
Subthalamus5.29 ± 0.1
Temporal Lobe4.67 ± 0.66
Thalamus5.22 ± 0.58
White Matter5.69 ± 0.82
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Flt1CBCerebellum29.1
21.56
Flt1CTXCerebral cortex22.6
13.53
Flt1HIPHippocampal region21.37
13.8
Flt1HPFHippocampal formation23.42
15.06
Flt1HYHypothalamus23.74
14.49
Flt1LSXLateral septal complex15.74
9.81
Flt1MBMidbrain19.39
13.4
Flt1MYMedulla33.01
20.1
Flt1OLFOlfactory bulb39.97
22.65
Flt1PPons26.71
16.59
Flt1PALPallidum15.83
9.92
Flt1RHPRetrohippocampal region25.5
15.78
Flt1sAMYStriatum-like amygdalar nuclei19.13
11.33
Flt1STRStriatum16.05
9.04
Flt1STRdStriatum dorsal region14.51
8.41
Flt1STRvStriatum ventral region19.65
9.17
Flt1THThalamus15.51
10.97
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp01429249 12 171 182 KFPLDTLIPDGK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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