AutismKB 2.0

Annotation Detail for XPO6


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Basic Information Top
Gene Symbol:XPO6 ( EXP6,FLJ22519,KIAA0370,RANBP20 )
Gene Full Name: exportin 6
Band: 16p11.2
Quick LinksEntrez ID:23214; OMIM: 608411; Uniprot ID:XPO6_HUMAN; ENSEMBL ID: ENSG00000169180; HGNC ID: 19733
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body7 / 7076198
blastocyst7 / 62319112
fetus53 / 56401293
neonate5 / 31097160
infant1 / 2362042
juvenile8 / 55556143
adult293 / 1939121151
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma5 / 17475286
breast (mammary gland) tumor10 / 94178106
cervical tumor5 / 34366145
chondrosarcoma13 / 82823156
colorectal tumor17 / 114246148
esophageal tumor0 / 172900 
gastrointestinal tumor17 / 119369142
germ cell tumor43 / 263845162
glioma11 / 106883102
head and neck tumor28 / 136302205
kidney tumor12 / 68959174
leukemia26 / 95842271
liver tumor3 / 9635931
lung tumor24 / 103127232
lymphoma17 / 71755236
non-neoplasia5 / 9725051
normal341 / 3360307101
ovarian tumor9 / 76682117
pancreatic tumor12 / 104616114
primitive neuroectodermal tumor of the CNS30 / 125680238
prostate cancer15 / 102680146
retinoblastoma3 / 4635664
skin tumor22 / 124949176
soft tissue/muscle tissue tumor24 / 125191191
uterine tumor11 / 90257121
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites10 / 40015249
bladder5 / 29757168
blood32 / 123478259
bone16 / 71655223
bone marrow1 / 4880120
brain133 / 1100989120
cervix17 / 48171352
connective tissue10 / 14925566
ear1 / 1621261
embryonic tissue20 / 21572292
esophagus0 / 202090 
eye18 / 21105485
heart6 / 8962666
intestine30 / 234472127
kidney24 / 211777113
larynx0 / 241450 
liver10 / 20774348
lung51 / 336974151
lymph14 / 44270316
lymph node13 / 91610141
mammary gland21 / 153271137
mouth8 / 67052119
muscle21 / 107715194
nerve4 / 15768253
ovary13 / 102051127
pancreas21 / 21481297
parathyroid1 / 2053948
pharynx7 / 41328169
pituitary gland1 / 1658560
placenta28 / 28082599
prostate18 / 18934595
salivary gland5 / 20155248
skin27 / 210574128
spleen10 / 53952185
stomach10 / 96619103
testis52 / 330442157
thymus11 / 81131135
thyroid8 / 47473168
tonsil3 / 16999176
trachea5 / 5241395
umbilical cord11 / 13680804
uterus36 / 232878154
vascular5 / 5178096
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 211982_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts579.15
Adipocyte73.55
AdrenalCortex91.4
Adrenalgland81.15
Amygdala133.45
Appendix76.2
AtrioventricularNode27.6
BDCA4+_DentriticCells343.85
Bonemarrow114.65
BronchialEpithelialCells97.05
CD105+_Endothelial399.85
CD14+_Monocytes438.25
CD19+_BCells(neg._sel.)635.9
CD33+_Myeloid257.4
CD34+317.75
CD4+_Tcells983.8
CD56+_NKCells628.75
CD71+_EarlyErythroid156.5
CD8+_Tcells784.9
CardiacMyocytes130.1
Caudatenucleus91.3
Cerebellum78.65
CerebellumPeduncles108.95
CiliaryGanglion50.55
CingulateCortex124.25
Colorectaladenocarcinoma102.65
DorsalRootGanglion38.85
FetalThyroid93.75
Fetalbrain99.9
Fetalliver54
Fetallung79.9
GlobusPallidus73.35
Heart55.25
Hypothalamus168.75
Kidney61.15
Leukemia_chronicMyelogenousK-56286.9
Leukemia_promyelocytic-HL-60170.7
Leukemialymphoblastic(MOLT-4)134.55
Liver126.95
Lung147.65
Lymphnode129.8
Lymphoma_burkitts(Daudi)140.45
Lymphoma_burkitts(Raji)345
MedullaOblongata122
OccipitalLobe91.5
OlfactoryBulb78.35
Ovary43.95
Pancreas65.95
PancreaticIslet57.75
ParietalLobe102.15
Pituitary106.4
Placenta188
Pons94.45
PrefrontalCortex251.4
Prostate128.45
Salivarygland76.8
SkeletalMuscle65.55
Skin42.35
SmoothMuscle204
Spinalcord132
SubthalamicNucleus91.05
SuperiorCervicalGanglion97.8
TemporalLobe93.25
Testis162.2
TestisGermCell212.1
TestisIntersitial194.15
TestisLeydigCell146.45
TestisSeminiferousTubule175.15
Thalamus103.75
Thymus128.85
Thyroid120.35
Tongue68.15
Tonsil123.4
Trachea68
TrigeminalGanglion94.4
Uterus71.15
UterusCorpus68.7
WholeBlood2703.25
Wholebrain153.1
colon104.4
pineal_day148.82
pineal_night145.8
retina123.15
small_intestine105.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_7219_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.19 ± 0.38
Basal Forebrain3.57 ± 0.59
Basal Part of Pons3.94 ± 0.48
Cerebellar Cortex4.07 ± 0.63
Cerebellar Nuclei3.79 ± 0.58
Claustrum4.05 ± 0.91
Epithalamus3.91 ± 0.56
Frontal Lobe4.2 ± 0.56
Globus Pallidus4.03 ± 0.6
Hypothalamus3.97 ± 0.77
Insula4.31 ± 0.52
Limbic Lobe4.18 ± 0.54
Mesencephalon4.02 ± 0.61
Myelencephalon4.06 ± 0.58
Occipital Lobe3.74 ± 0.54
Parietal Lobe4.1 ± 0.47
Pontine Tegmentum4.12 ± 0.57
Striatum3.87 ± 0.57
Subthalamus4.29 ± 0.54
Temporal Lobe4.16 ± 0.58
Thalamus3.92 ± 0.58
White Matter4.86 ± 0.26
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
XPO6_HUMAN_2 8 2 9 ASEEASLR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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