AutismKB 2.0

Annotation Detail for XPO6


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Basic Information Top
Gene Symbol:XPO6 ( EXP6,FLJ22519,KIAA0370,RANBP20 )
Gene Full Name: exportin 6
Band: 16p11.2
Quick LinksEntrez ID:23214; OMIM: 608411; Uniprot ID:XPO6_HUMAN; ENSEMBL ID: ENSG00000169180; HGNC ID: 19733
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body7 / 7076198
blastocyst7 / 62319112
fetus53 / 56401293
neonate5 / 31097160
infant1 / 2362042
juvenile8 / 55556143
adult293 / 1939121151
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 211982_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts579.15
Adipocyte73.55
AdrenalCortex91.4
Adrenalgland81.15
Amygdala133.45
Appendix76.2
AtrioventricularNode27.6
BDCA4+_DentriticCells343.85
Bonemarrow114.65
BronchialEpithelialCells97.05
CD105+_Endothelial399.85
CD14+_Monocytes438.25
CD19+_BCells(neg._sel.)635.9
CD33+_Myeloid257.4
CD34+317.75
CD4+_Tcells983.8
CD56+_NKCells628.75
CD71+_EarlyErythroid156.5
CD8+_Tcells784.9
CardiacMyocytes130.1
Caudatenucleus91.3
Cerebellum78.65
CerebellumPeduncles108.95
CiliaryGanglion50.55
CingulateCortex124.25
Colorectaladenocarcinoma102.65
DorsalRootGanglion38.85
FetalThyroid93.75
Fetalbrain99.9
Fetalliver54
Fetallung79.9
GlobusPallidus73.35
Heart55.25
Hypothalamus168.75
Kidney61.15
Leukemia_chronicMyelogenousK-56286.9
Leukemia_promyelocytic-HL-60170.7
Leukemialymphoblastic(MOLT-4)134.55
Liver126.95
Lung147.65
Lymphnode129.8
Lymphoma_burkitts(Daudi)140.45
Lymphoma_burkitts(Raji)345
MedullaOblongata122
OccipitalLobe91.5
OlfactoryBulb78.35
Ovary43.95
Pancreas65.95
PancreaticIslet57.75
ParietalLobe102.15
Pituitary106.4
Placenta188
Pons94.45
PrefrontalCortex251.4
Prostate128.45
Salivarygland76.8
SkeletalMuscle65.55
Skin42.35
SmoothMuscle204
Spinalcord132
SubthalamicNucleus91.05
SuperiorCervicalGanglion97.8
TemporalLobe93.25
Testis162.2
TestisGermCell212.1
TestisIntersitial194.15
TestisLeydigCell146.45
TestisSeminiferousTubule175.15
Thalamus103.75
Thymus128.85
Thyroid120.35
Tongue68.15
Tonsil123.4
Trachea68
TrigeminalGanglion94.4
Uterus71.15
UterusCorpus68.7
WholeBlood2703.25
Wholebrain153.1
colon104.4
pineal_day148.82
pineal_night145.8
retina123.15
small_intestine105.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_7219_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.19 ± 0.38
Basal Forebrain3.57 ± 0.59
Basal Part of Pons3.94 ± 0.48
Cerebellar Cortex4.07 ± 0.63
Cerebellar Nuclei3.79 ± 0.58
Claustrum4.05 ± 0.91
Epithalamus3.91 ± 0.56
Frontal Lobe4.2 ± 0.56
Globus Pallidus4.03 ± 0.6
Hypothalamus3.97 ± 0.77
Insula4.31 ± 0.52
Limbic Lobe4.18 ± 0.54
Mesencephalon4.02 ± 0.61
Myelencephalon4.06 ± 0.58
Occipital Lobe3.74 ± 0.54
Parietal Lobe4.1 ± 0.47
Pontine Tegmentum4.12 ± 0.57
Striatum3.87 ± 0.57
Subthalamus4.29 ± 0.54
Temporal Lobe4.16 ± 0.58
Thalamus3.92 ± 0.58
White Matter4.86 ± 0.26
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
XPO6_HUMAN_2 8 2 9 ASEEASLR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018