Annotation Detail for RHOBTB2
Basic Information Top
| Gene Symbol: | RHOBTB2 ( DBC2,KIAA0717 ) |
|---|---|
| Gene Full Name: | Rho-related BTB domain containing 2 |
| Band: | 8p21.3 |
| Quick Links | Entrez ID:23221; OMIM: 607352; Uniprot ID:RHBT2_HUMAN; ENSEMBL ID: ENSG00000008853; HGNC ID: 18756 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.372688
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 1 / 70761 | 14 |  |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 16 / 564012 | 28 | |
| neonate | 0 / 31097 | 0 | |
| infant | 1 / 23620 | 42 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 48 / 1939121 | 24 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 1 / 94178 | 10 |  |
| cervical tumor | 2 / 34366 | 58 |  |
| chondrosarcoma | 5 / 82823 | 60 | |
| colorectal tumor | 0 / 114246 | 0 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 3 / 119369 | 25 | |
| germ cell tumor | 15 / 263845 | 56 | |
| glioma | 4 / 106883 | 37 | |
| head and neck tumor | 4 / 136302 | 29 | |
| kidney tumor | 0 / 68959 | 0 | |
| leukemia | 2 / 95842 | 20 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 3 / 103127 | 29 | |
| lymphoma | 9 / 71755 | 125 | |
| non-neoplasia | 2 / 97250 | 20 | |
| normal | 151 / 3360307 | 44 | |
| ovarian tumor | 0 / 76682 | 0 | |
| pancreatic tumor | 1 / 104616 | 9 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 3 / 102680 | 29 | |
| retinoblastoma | 2 / 46356 | 43 | |
| skin tumor | 2 / 124949 | 16 | |
| soft tissue/muscle tissue tumor | 2 / 125191 | 15 | |
| uterine tumor | 1 / 90257 | 11 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 1 / 40015 | 24 | |
| bladder | 5 / 29757 | 168 | |
| blood | 0 / 123478 | 0 | |
| bone | 2 / 71655 | 27 | |
| bone marrow | 1 / 48801 | 20 | |
| brain | 67 / 1100989 | 60 | |
| cervix | 2 / 48171 | 41 | |
| connective tissue | 3 / 149255 | 20 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 3 / 215722 | 13 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 14 / 211054 | 66 | |
| heart | 1 / 89626 | 11 | |
| intestine | 3 / 234472 | 12 | |
| kidney | 8 / 211777 | 37 | |
| larynx | 0 / 24145 | 0 | |
| liver | 0 / 207743 | 0 | |
| lung | 20 / 336974 | 59 | |
| lymph | 8 / 44270 | 180 | |
| lymph node | 12 / 91610 | 130 | |
| mammary gland | 1 / 153271 | 6 | |
| mouth | 1 / 67052 | 14 | |
| muscle | 4 / 107715 | 37 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 0 / 102051 | 0 | |
| pancreas | 2 / 214812 | 9 | |
| parathyroid | 1 / 20539 | 48 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 7 / 280825 | 24 | |
| prostate | 8 / 189345 | 42 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 3 / 210574 | 14 | |
| spleen | 2 / 53952 | 37 | |
| stomach | 2 / 96619 | 20 | |
| testis | 7 / 330442 | 21 | |
| thymus | 1 / 81131 | 12 | |
| thyroid | 4 / 47473 | 84 | |
| tonsil | 2 / 16999 | 117 | |
| trachea | 5 / 52413 | 95 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 7 / 232878 | 30 | |
| vascular | 0 / 51780 | 0 |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 209441_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 7.4 | |
| Adipocyte | 5.8 | |
| AdrenalCortex | 6.25 | |
| Adrenalgland | 5.05 | |
| Amygdala | 7.45 | |
| Appendix | 6.1 | |
| AtrioventricularNode | 5.65 | |
| BDCA4+_DentriticCells | 6.45 | |
| Bonemarrow | 6.5 | |
| BronchialEpithelialCells | 5.85 | |
| CD105+_Endothelial | 5.9 | |
| CD14+_Monocytes | 6.5 | |
| CD19+_BCells(neg._sel.) | 9.35 | |
| CD33+_Myeloid | 7.75 | |
| CD34+ | 7.4 | |
| CD4+_Tcells | 6.2 | |
| CD56+_NKCells | 7.45 | |
| CD71+_EarlyErythroid | 5.6 | |
| CD8+_Tcells | 5.25 | |
| CardiacMyocytes | 7.65 | |
| Caudatenucleus | 14.1 | |
| Cerebellum | 5 | |
| CerebellumPeduncles | 7.25 | |
| CiliaryGanglion | 4.35 | |
| CingulateCortex | 12 | |
| Colorectaladenocarcinoma | 6.15 | |
| DorsalRootGanglion | 5.45 | |
| FetalThyroid | 5.95 | |
| Fetalbrain | 7.25 | |
| Fetalliver | 5.15 | |
| Fetallung | 8 | |
| GlobusPallidus | 10.05 | |
| Heart | 8.25 | |
| Hypothalamus | 7.6 | |
| Kidney | 5 | |
| Leukemia_chronicMyelogenousK-562 | 5.5 | |
| Leukemia_promyelocytic-HL-60 | 5.25 | |
| Leukemialymphoblastic(MOLT-4) | 4.9 | |
| Liver | 8 | |
| Lung | 30.6 | |
| Lymphnode | 5.35 | |
| Lymphoma_burkitts(Daudi) | 12.95 | |
| Lymphoma_burkitts(Raji) | 9.15 | |
| MedullaOblongata | 7.35 | |
| OccipitalLobe | 7.3 | |
| OlfactoryBulb | 4.85 | |
| Ovary | 4.05 | |
| Pancreas | 4.95 | |
| PancreaticIslet | 7.4 | |
| ParietalLobe | 9.3 | |
| Pituitary | 7.25 | |
| Placenta | 6.1 | |
| Pons | 6.7 | |
| PrefrontalCortex | 13.95 | |
| Prostate | 6.9 | |
| Salivarygland | 4.9 | |
| SkeletalMuscle | 6.95 | |
| Skin | 5.05 | |
| SmoothMuscle | 6.9 | |
| Spinalcord | 6.5 | |
| SubthalamicNucleus | 10.4 | |
| SuperiorCervicalGanglion | 7.05 | |
| TemporalLobe | 7.7 | |
| Testis | 5.3 | |
| TestisGermCell | 5.05 | |
| TestisIntersitial | 5 | |
| TestisLeydigCell | 6.05 | |
| TestisSeminiferousTubule | 5.6 | |
| Thalamus | 6.3 | |
| Thymus | 4.6 | |
| Thyroid | 7.8 | |
| Tongue | 5.9 | |
| Tonsil | 5.95 | |
| Trachea | 5.15 | |
| TrigeminalGanglion | 5.95 | |
| Uterus | 4.95 | |
| UterusCorpus | 5.45 | |
| WholeBlood | 5.25 | |
| Wholebrain | 11.55 | |
| colon | 5.8 | |
| pineal_day | 12.16 | |
| pineal_night | 10.5 | |
| retina | 7.525 | |
| small_intestine | 5.7 | |
- Probe name: CUST_16616_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 8.41 ± 0.57 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 8.64 ± 0.68 | |
| Basal Part of Pons | 9.91 ± 0.42 | |
| Cerebellar Cortex | 8.34 ± 0.56 | |
| Cerebellar Nuclei | 10.67 ± 0.72 | |
| Claustrum | 8.59 ± 0.62 | |
| Epithalamus | 7.31 ± 0.77 | |
| Frontal Lobe | 9.21 ± 1.03 | |
| Globus Pallidus | 10.5 ± 0.73 | |
| Hypothalamus | 8.52 ± 0.61 | |
| Insula | 8.17 ± 0.64 | |
| Limbic Lobe | 8.73 ± 0.59 | |
| Mesencephalon | 9.07 ± 0.93 | |
| Myelencephalon | 9.04 ± 0.9 | |
| Occipital Lobe | 9.53 ± 0.52 | |
| Parietal Lobe | 9.43 ± 0.67 | |
| Pontine Tegmentum | 9.07 ± 1.08 | |
| Striatum | 8.8 ± 0.64 | |
| Subthalamus | 9.69 ± 0.17 | |
| Temporal Lobe | 8.6 ± 0.63 | |
| Thalamus | 9.58 ± 0.79 | |
| White Matter | 6.38 ± 0.94 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Rhobtb2 | CB | Cerebellum | 0 | |
| 0 | | |||
| Rhobtb2 | CTX | Cerebral cortex | 0 | |
| 0 | | |||
| Rhobtb2 | HIP | Hippocampal region | 0 | |
| 0 | | |||
| Rhobtb2 | HPF | Hippocampal formation | 0 | |
| 0 | | |||
| Rhobtb2 | HY | Hypothalamus | 0 | |
| 0 | | |||
| Rhobtb2 | LSX | Lateral septal complex | 0 | |
| 0 | | |||
| Rhobtb2 | MB | Midbrain | 0 | |
| 0 | | |||
| Rhobtb2 | MY | Medulla | 0 | |
| 0 | | |||
| Rhobtb2 | OLF | Olfactory bulb | 0 | |
| 0 | | |||
| Rhobtb2 | P | Pons | 0 | |
| 0 | | |||
| Rhobtb2 | PAL | Pallidum | 0 | |
| 0 | | |||
| Rhobtb2 | RHP | Retrohippocampal region | 0 | |
| 0 | | |||
| Rhobtb2 | sAMY | Striatum-like amygdalar nuclei | 0 | |
| 0 | | |||
| Rhobtb2 | STR | Striatum | 0 | |
| 0 | | |||
| Rhobtb2 | STRd | Striatum dorsal region | 0 | |
| 0 | | |||
| Rhobtb2 | STRv | Striatum ventral region | 0 | |
| 0 | | |||
| Rhobtb2 | TH | Thalamus | 0 | |
| 0 | |
Peptide