Annotation Detail for SYNE2
Basic Information Top
| Gene Symbol: | SYNE2 ( DKFZp434H2235,DKFZp686E01115,DKFZp686H1931,EDMD5,FLJ11014,FLJ43727,FLJ45710,FLJ46790,KIAA1011,NUA,NUANCE,Nesprin-2,SYNE-2,TROPH ) |
|---|---|
| Gene Full Name: | spectrin repeat containing, nuclear envelope 2 |
| Band: | 14q23.2 |
| Quick Links | Entrez ID:23224; OMIM: 608442; Uniprot ID:SYNE2_HUMAN; ENSEMBL ID: ENSG00000054654; HGNC ID: 17084 |
| Relate to Another Database: | SFARIGene; denovo-db |
Unigene EST- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 202761_s_at
| Cell line | Expression level | Expression bar |
|---|---|---|
 | ||
| 721_B_lymphoblasts | 32.7 |  |
| Adipocyte | 11.85 | |
| AdrenalCortex | 18.45 | |
| Adrenalgland | 15.2 | |
| Amygdala | 17.1 | |
| Appendix | 19.45 | |
| AtrioventricularNode | 13.35 | |
| BDCA4+_DentriticCells | 28 | |
| Bonemarrow | 13.25 | |
| BronchialEpithelialCells | 16.75 | |
| CD105+_Endothelial | 15.8 | |
| CD14+_Monocytes | 12.6 | |
| CD19+_BCells(neg._sel.) | 42.8 | |
| CD33+_Myeloid | 9.65 |  |
| CD34+ | 13.25 | |
| CD4+_Tcells | 388.65 |  |
| CD56+_NKCells | 551.8 | |
| CD71+_EarlyErythroid | 11.75 | |
| CD8+_Tcells | 688.65 | |
| CardiacMyocytes | 21.95 | |
| Caudatenucleus | 13.05 | |
| Cerebellum | 15.4 | |
| CerebellumPeduncles | 33.55 | |
| CiliaryGanglion | 12.3 | |
| CingulateCortex | 15 | |
| Colorectaladenocarcinoma | 21.6 | |
| DorsalRootGanglion | 13.45 | |
| FetalThyroid | 150.4 |  |
| Fetalbrain | 20.2 | |
| Fetalliver | 13 | |
| Fetallung | 24.35 | |
| GlobusPallidus | 12.6 | |
| Heart | 86.45 | |
| Hypothalamus | 18.75 | |
| Kidney | 47.9 | |
| Leukemia_chronicMyelogenousK-562 | 15.05 | |
| Leukemia_promyelocytic-HL-60 | 105.35 | |
| Leukemialymphoblastic(MOLT-4) | 24.95 | |
| Liver | 23.55 | |
| Lung | 61.65 | |
| Lymphnode | 37.1 | |
| Lymphoma_burkitts(Daudi) | 353.6 | |
| Lymphoma_burkitts(Raji) | 146 | |
| MedullaOblongata | 11.35 | |
| OccipitalLobe | 15.2 | |
| OlfactoryBulb | 15.05 | |
| Ovary | 28.75 | |
| Pancreas | 59.6 | |
| PancreaticIslet | 72.45 | |
| ParietalLobe | 18.1 | |
| Pituitary | 86.6 | |
| Placenta | 38.85 | |
| Pons | 16.2 | |
| PrefrontalCortex | 20.85 | |
| Prostate | 50.2 | |
| Salivarygland | 40.55 | |
| SkeletalMuscle | 99 | |
| Skin | 21.9 | |
| SmoothMuscle | 15.3 | |
| Spinalcord | 18.6 | |
| SubthalamicNucleus | 15.25 | |
| SuperiorCervicalGanglion | 19.45 | |
| TemporalLobe | 11.8 | |
| Testis | 34.45 | |
| TestisGermCell | 170.65 | |
| TestisIntersitial | 29.15 | |
| TestisLeydigCell | 28.25 | |
| TestisSeminiferousTubule | 23.15 | |
| Thalamus | 17.5 | |
| Thymus | 21.5 | |
| Thyroid | 535.55 | |
| Tongue | 49.6 | |
| Tonsil | 34.05 | |
| Trachea | 32.55 | |
| TrigeminalGanglion | 18 | |
| Uterus | 50.95 | |
| UterusCorpus | 17.45 | |
| WholeBlood | 45.1 | |
| Wholebrain | 12.25 | |
| colon | 127.35 | |
| pineal_day | 60.56 | |
| pineal_night | 76.24 | |
| retina | 113.1 | |
| small_intestine | 67.35 | |
- Probe name: A_24_P68311
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 5.01 ± 0.42 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 5.36 ± 0.26 | |
| Basal Part of Pons | 4.9 ± 0.42 | |
| Cerebellar Cortex | 5.95 ± 0.33 | |
| Cerebellar Nuclei | 5.9 ± 0.19 | |
| Claustrum | 4.91 ± 0.64 | |
| Epithalamus | 6.28 ± 0.49 | |
| Frontal Lobe | 5.14 ± 0.61 | |
| Globus Pallidus | 6.09 ± 0.87 | |
| Hypothalamus | 5.12 ± 0.65 | |
| Insula | 4.86 ± 0.82 | |
| Limbic Lobe | 5.05 ± 0.7 | |
| Mesencephalon | 5.5 ± 0.6 | |
| Myelencephalon | 5.42 ± 0.6 | |
| Occipital Lobe | 5.55 ± 0.59 | |
| Parietal Lobe | 5.12 ± 0.56 | |
| Pontine Tegmentum | 5.38 ± 0.67 | |
| Striatum | 5.74 ± 0.85 | |
| Subthalamus | 5.47 ± 0.92 | |
| Temporal Lobe | 5.15 ± 0.46 | |
| Thalamus | 5.52 ± 0.49 | |
| White Matter | 6.49 ± 0.82 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Syne2 | CB | Cerebellum | 22.63 | |
| 26.9 | | |||
| Syne2 | CTX | Cerebral cortex | 1.14 | |
| 1.18 | | |||
| Syne2 | HIP | Hippocampal region | 2.19 | |
| 2.2 | | |||
| Syne2 | HPF | Hippocampal formation | 1.71 | |
| 1.59 | | |||
| Syne2 | HY | Hypothalamus | 0.68 | |
| 0.66 | | |||
| Syne2 | LSX | Lateral septal complex | 1.82 | |
| 2.44 | | |||
| Syne2 | MB | Midbrain | 1.55 | |
| 1.76 | | |||
| Syne2 | MY | Medulla | 6.68 | |
| 8.66 | | |||
| Syne2 | OLF | Olfactory bulb | 3.95 | |
| 3.06 | | |||
| Syne2 | P | Pons | 1.22 | |
| 1.34 | | |||
| Syne2 | PAL | Pallidum | 0.76 | |
| 0.74 | | |||
| Syne2 | RHP | Retrohippocampal region | 1.06 | |
| 0.9 | | |||
| Syne2 | sAMY | Striatum-like amygdalar nuclei | 0.45 | |
| 0.46 | | |||
| Syne2 | STR | Striatum | 1.3 | |
| 1.82 | | |||
| Syne2 | STRd | Striatum dorsal region | 1.38 | |
| 2.12 | | |||
| Syne2 | STRv | Striatum ventral region | 0.44 | |
| 0.53 | | |||
| Syne2 | TH | Thalamus | 0.81 | |
| 0.78 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00040141 | 29 | 5529 | 5557 | ENPDSFLNHVLALTAQSPDIEHLNEVSLK | Peptide Atlas |
| SYNE2_HUMAN_1050 | 11 | 1050 | 1060 | NEGTITTSENR | PRIDE |
| SYNE2_HUMAN_6233 | 7 | 6233 | 6239 | VTAVLRR | PRIDE |