AutismKB 2.0

Annotation Detail for ANKRD12


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Basic Information Top
Gene Symbol:ANKRD12 ( ANCO-2,ANCO1,FLJ20053,GAC-1,KIAA0874,Nbla00144 )
Gene Full Name: ankyrin repeat domain 12
Band: 18p11.22
Quick LinksEntrez ID:23253; OMIM: 610616; Uniprot ID:ANR12_HUMAN; ENSEMBL ID: ENSG00000101745; HGNC ID: 29135
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst4 / 6231964
fetus38 / 56401267
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult91 / 193912146
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor7 / 9417874
cervical tumor3 / 3436687
chondrosarcoma6 / 8282372
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor7 / 11936958
germ cell tumor10 / 26384537
glioma6 / 10688356
head and neck tumor4 / 13630229
kidney tumor1 / 6895914
leukemia7 / 9584273
liver tumor5 / 9635951
lung tumor0 / 1031270 
lymphoma4 / 7175555
non-neoplasia3 / 9725030
normal201 / 336030759
ovarian tumor3 / 7668239
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer2 / 10268019
retinoblastoma2 / 4635643
skin tumor2 / 12494916
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites1 / 4001524
bladder3 / 29757100
blood6 / 12347848
bone3 / 7165541
bone marrow4 / 4880181
brain37 / 110098933
cervix3 / 4817162
connective tissue7 / 14925546
ear0 / 162120 
embryonic tissue14 / 21572264
esophagus0 / 202090 
eye13 / 21105461
heart1 / 8962611
intestine2 / 2344728
kidney15 / 21177770
larynx1 / 2414541
liver13 / 20774362
lung12 / 33697435
lymph2 / 4427045
lymph node11 / 91610120
mammary gland11 / 15327171
mouth2 / 6705229
muscle8 / 10771574
nerve1 / 1576863
ovary3 / 10205129
pancreas10 / 21481246
parathyroid0 / 205390 
pharynx6 / 41328145
pituitary gland1 / 1658560
placenta14 / 28082549
prostate5 / 18934526
salivary gland0 / 201550 
skin3 / 21057414
spleen8 / 53952148
stomach6 / 9661962
testis28 / 33044284
thymus9 / 81131110
thyroid2 / 4747342
tonsil0 / 169990 
trachea4 / 5241376
umbilical cord0 / 136800 
uterus12 / 23287851
vascular5 / 5178096
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 212286_at
Cell line Expression level Expression bar
721_B_lymphoblasts15.9
Adipocyte4.75
AdrenalCortex5.05
Adrenalgland4
Amygdala4.8
Appendix5.6
AtrioventricularNode3.75
BDCA4+_DentriticCells101.85
Bonemarrow4.75
BronchialEpithelialCells4.4
CD105+_Endothelial5.05
CD14+_Monocytes6.05
CD19+_BCells(neg._sel.)51.2
CD33+_Myeloid29.55
CD34+9.8
CD4+_Tcells92
CD56+_NKCells64.1
CD71+_EarlyErythroid4.8
CD8+_Tcells66.15
CardiacMyocytes6.5
Caudatenucleus4.35
Cerebellum3.85
CerebellumPeduncles5.45
CiliaryGanglion6.95
CingulateCortex5
Colorectaladenocarcinoma4.7
DorsalRootGanglion3.8
FetalThyroid4.65
Fetalbrain6.8
Fetalliver4.1
Fetallung4
GlobusPallidus4.3
Heart6.1
Hypothalamus5.25
Kidney3.9
Leukemia_chronicMyelogenousK-5624.15
Leukemia_promyelocytic-HL-604.25
Leukemialymphoblastic(MOLT-4)3.55
Liver6.35
Lung4.9
Lymphnode9.5
Lymphoma_burkitts(Daudi)6.1
Lymphoma_burkitts(Raji)6.75
MedullaOblongata4.4
OccipitalLobe5.05
OlfactoryBulb3.8
Ovary3.15
Pancreas3.85
PancreaticIslet5.15
ParietalLobe5.15
Pituitary5.6
Placenta4.75
Pons4.6
PrefrontalCortex6.3
Prostate5.15
Salivarygland3.95
SkeletalMuscle5.65
Skin3.75
SmoothMuscle5
Spinalcord5.05
SubthalamicNucleus4.4
SuperiorCervicalGanglion5.75
TemporalLobe4.4
Testis3.95
TestisGermCell4.8
TestisIntersitial4.45
TestisLeydigCell4.95
TestisSeminiferousTubule4.5
Thalamus4.9
Thymus3.45
Thyroid5.55
Tongue4.7
Tonsil5.1
Trachea3.95
TrigeminalGanglion4.85
Uterus3.95
UterusCorpus4.45
WholeBlood20.95
Wholebrain4.05
colon4.5
pineal_day6.12
pineal_night6.62
retina5.525
small_intestine4.35
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P130293
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.83 ± 0.29
Basal Forebrain8.16 ± 0.16
Basal Part of Pons7.69 ± 0.24
Cerebellar Cortex8.21 ± 0.15
Cerebellar Nuclei7.64 ± 0.13
Claustrum8.41 ± 0.29
Epithalamus7.69 ± 0.33
Frontal Lobe7.86 ± 0.28
Globus Pallidus7.45 ± 0.17
Hypothalamus7.95 ± 0.34
Insula7.87 ± 0.3
Limbic Lobe7.88 ± 0.29
Mesencephalon8.02 ± 0.32
Myelencephalon7.89 ± 0.3
Occipital Lobe8.15 ± 0.23
Parietal Lobe7.87 ± 0.3
Pontine Tegmentum7.9 ± 0.33
Striatum7.64 ± 0.27
Subthalamus7.79 ± 0.33
Temporal Lobe7.87 ± 0.25
Thalamus7.85 ± 0.34
White Matter8.45 ± 0.21
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ankrd12CBCerebellum9.26
8.98
Ankrd12CTXCerebral cortex9.86
7.64
Ankrd12HIPHippocampal region12.04
12.99
Ankrd12HPFHippocampal formation11.9
11.44
Ankrd12HYHypothalamus0.27
0.21
Ankrd12LSXLateral septal complex0.91
0.63
Ankrd12MBMidbrain2.46
2.82
Ankrd12MYMedulla5.92
6.12
Ankrd12OLFOlfactory bulb7.48
5.5
Ankrd12PPons1.88
1.97
Ankrd12PALPallidum0.89
0.84
Ankrd12RHPRetrohippocampal region11.96
9.58
Ankrd12sAMYStriatum-like amygdalar nuclei2.35
1.99
Ankrd12STRStriatum1.37
1.12
Ankrd12STRdStriatum dorsal region1.44
1.23
Ankrd12STRvStriatum ventral region0.91
0.63
Ankrd12THThalamus1.83
2.07
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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