AutismKB 2.0

Annotation Detail for ZC3H7B


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Basic Information Top
Gene Symbol:ZC3H7B ( DKFZp434K0920,FLJ13787,KIAA1031,RoXaN )
Gene Full Name: zinc finger CCCH-type containing 7B
Band: 22q13.2
Quick LinksEntrez ID:23264; OMIM: NA; Uniprot ID:Z3H7B_HUMAN; ENSEMBL ID: ENSG00000100403; HGNC ID: 30869
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst2 / 6231932
fetus17 / 56401230
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult57 / 193912129
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor7 / 9417874
cervical tumor1 / 3436629
chondrosarcoma4 / 8282348
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor7 / 26384526
glioma11 / 106883102
head and neck tumor7 / 13630251
kidney tumor3 / 6895943
leukemia2 / 9584220
liver tumor3 / 9635931
lung tumor2 / 10312719
lymphoma5 / 7175569
non-neoplasia2 / 9725020
normal104 / 336030730
ovarian tumor3 / 7668239
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer3 / 10268029
retinoblastoma0 / 463560 
skin tumor10 / 12494980
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor7 / 9025777
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood3 / 12347824
bone1 / 7165513
bone marrow0 / 488010 
brain60 / 110098954
cervix3 / 4817162
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue10 / 21572246
esophagus0 / 202090 
eye11 / 21105452
heart1 / 8962611
intestine6 / 23447225
kidney8 / 21177737
larynx0 / 241450 
liver4 / 20774319
lung7 / 33697420
lymph5 / 44270112
lymph node6 / 9161065
mammary gland8 / 15327152
mouth7 / 67052104
muscle1 / 1077159
nerve1 / 1576863
ovary4 / 10205139
pancreas2 / 2148129
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta4 / 28082514
prostate7 / 18934536
salivary gland0 / 201550 
skin11 / 21057452
spleen2 / 5395237
stomach6 / 9661962
testis3 / 3304429
thymus5 / 8113161
thyroid2 / 4747342
tonsil0 / 169990 
trachea5 / 5241395
umbilical cord0 / 136800 
uterus11 / 23287847
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 213323_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts4.1
Adipocyte3.15
AdrenalCortex3.25
Adrenalgland2.65
Amygdala3.35
Appendix3.35
AtrioventricularNode2.35
BDCA4+_DentriticCells3.55
Bonemarrow3.05
BronchialEpithelialCells3.1
CD105+_Endothelial3.2
CD14+_Monocytes3.4
CD19+_BCells(neg._sel.)3.4
CD33+_Myeloid4.05
CD34+4.05
CD4+_Tcells3.45
CD56+_NKCells3.8
CD71+_EarlyErythroid2.95
CD8+_Tcells3.1
CardiacMyocytes3.95
Caudatenucleus2.8
Cerebellum2.55
CerebellumPeduncles3.55
CiliaryGanglion2.15
CingulateCortex3.25
Colorectaladenocarcinoma3.15
DorsalRootGanglion2.5
FetalThyroid3.3
Fetalbrain3.15
Fetalliver2.7
Fetallung2.65
GlobusPallidus2.3
Heart3.95
Hypothalamus3.45
Kidney2.5
Leukemia_chronicMyelogenousK-5622.85
Leukemia_promyelocytic-HL-602.8
Leukemialymphoblastic(MOLT-4)2.6
Liver4.15
Lung3.5
Lymphnode2.7
Lymphoma_burkitts(Daudi)4
Lymphoma_burkitts(Raji)4.4
MedullaOblongata2.95
OccipitalLobe2.85
OlfactoryBulb2.5
Ovary2.05
Pancreas2.5
PancreaticIslet3.35
ParietalLobe3.3
Pituitary3.7
Placenta3.25
Pons3
PrefrontalCortex4.15
Prostate3.7
Salivarygland2.5
SkeletalMuscle3.6
Skin2.4
SmoothMuscle3.6
Spinalcord4.6
SubthalamicNucleus2.85
SuperiorCervicalGanglion3.55
TemporalLobe7.45
Testis2.7
TestisGermCell2.65
TestisIntersitial2.65
TestisLeydigCell3.1
TestisSeminiferousTubule2.7
Thalamus3.2
Thymus2.5
Thyroid4
Tongue3.05
Tonsil3.05
Trachea2.65
TrigeminalGanglion3.6
Uterus2.6
UterusCorpus2.8
WholeBlood3.5
Wholebrain2.75
colon3.15
pineal_day3.96
pineal_night3.86
retina4
small_intestine3.1
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_8936_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.32 ± 0.47
Basal Forebrain6.98 ± 0.49
Basal Part of Pons7.52 ± 0.36
Cerebellar Cortex6.9 ± 0.42
Cerebellar Nuclei7.18 ± 0.35
Claustrum7.85 ± 0.52
Epithalamus6.56 ± 0.41
Frontal Lobe6.99 ± 0.45
Globus Pallidus7.45 ± 0.29
Hypothalamus6.62 ± 0.51
Insula6.89 ± 0.43
Limbic Lobe7.18 ± 0.51
Mesencephalon7.09 ± 0.47
Myelencephalon7.11 ± 0.49
Occipital Lobe7.45 ± 0.39
Parietal Lobe7.23 ± 0.49
Pontine Tegmentum6.99 ± 0.52
Striatum7.19 ± 0.49
Subthalamus7.33 ± 0.22
Temporal Lobe6.98 ± 0.44
Thalamus7.06 ± 0.4
White Matter7.78 ± 0.5
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Zc3h7bCBCerebellum8
10.09
Zc3h7bCTXCerebral cortex11.5
7.65
Zc3h7bHIPHippocampal region13.23
12.39
Zc3h7bHPFHippocampal formation14.1
12.05
Zc3h7bHYHypothalamus1.31
0.95
Zc3h7bLSXLateral septal complex2.49
2.01
Zc3h7bMBMidbrain3.88
3.8
Zc3h7bMYMedulla6.45
6.32
Zc3h7bOLFOlfactory bulb14.69
11.63
Zc3h7bPPons3.09
3
Zc3h7bPALPallidum2.48
2.11
Zc3h7bRHPRetrohippocampal region15.79
11.57
Zc3h7bsAMYStriatum-like amygdalar nuclei9.56
6.28
Zc3h7bSTRStriatum5.23
3.72
Zc3h7bSTRdStriatum dorsal region5.68
4.2
Zc3h7bSTRvStriatum ventral region2.1
1.34
Zc3h7bTHThalamus4
3.21
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00026113 17 768 784 KCQYVGNCSFAHSPEER Peptide Atlas
Z3H7B_HUMAN_900 7 900 906 FPMGEFR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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