AutismKB 2.0

Annotation Detail for DNMBP


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:DNMBP ( ARHGEF36,KIAA1010,TUBA )
Gene Full Name: dynamin binding protein
Band: 10q24.2
Quick LinksEntrez ID:23268; OMIM: 611282; Uniprot ID:DNMBP_HUMAN; ENSEMBL ID: ENSG00000107554; HGNC ID: 30373
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body7 / 7076198
blastocyst3 / 6231948
fetus22 / 56401239
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult73 / 193912137
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma4 / 8282348
colorectal tumor5 / 11424643
esophageal tumor0 / 172900 
gastrointestinal tumor7 / 11936958
germ cell tumor2 / 2638457
glioma2 / 10688318
head and neck tumor3 / 13630222
kidney tumor2 / 6895929
leukemia9 / 9584293
liver tumor2 / 9635920
lung tumor1 / 1031279
lymphoma3 / 7175541
non-neoplasia2 / 9725020
normal89 / 336030726
ovarian tumor1 / 7668213
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer2 / 10268019
retinoblastoma1 / 4635621
skin tumor1 / 1249498
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites5 / 40015124
bladder0 / 297570 
blood9 / 12347872
bone2 / 7165527
bone marrow0 / 488010 
brain13 / 110098911
cervix0 / 481710 
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue16 / 21572274
esophagus0 / 202090 
eye7 / 21105433
heart0 / 896260 
intestine9 / 23447238
kidney12 / 21177756
larynx0 / 241450 
liver5 / 20774324
lung10 / 33697429
lymph3 / 4427067
lymph node2 / 9161021
mammary gland1 / 1532716
mouth1 / 6705214
muscle1 / 1077159
nerve0 / 157680 
ovary1 / 1020519
pancreas4 / 21481218
parathyroid5 / 20539243
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta9 / 28082532
prostate2 / 18934510
salivary gland2 / 2015599
skin5 / 21057423
spleen1 / 5395218
stomach2 / 9661920
testis7 / 33044221
thymus5 / 8113161
thyroid2 / 4747342
tonsil0 / 169990 
trachea4 / 5241376
umbilical cord0 / 136800 
uterus13 / 23287855
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 212838_at
Cell line Expression level Expression bar
721_B_lymphoblasts63.85
Adipocyte62.25
AdrenalCortex51.25
Adrenalgland57.55
Amygdala29.5
Appendix57.45
AtrioventricularNode64.3
BDCA4+_DentriticCells12.95
Bonemarrow45.65
BronchialEpithelialCells49.45
CD105+_Endothelial22.75
CD14+_Monocytes22.9
CD19+_BCells(neg._sel.)48.15
CD33+_Myeloid35.9
CD34+26
CD4+_Tcells14.75
CD56+_NKCells23.8
CD71+_EarlyErythroid24.45
CD8+_Tcells12.75
CardiacMyocytes63.85
Caudatenucleus39.1
Cerebellum47.35
CerebellumPeduncles57.9
CiliaryGanglion33.95
CingulateCortex44.1
Colorectaladenocarcinoma64.45
DorsalRootGanglion39.8
FetalThyroid66.35
Fetalbrain36
Fetalliver37.8
Fetallung81.95
GlobusPallidus37
Heart44.8
Hypothalamus41.65
Kidney86.2
Leukemia_chronicMyelogenousK-56235.05
Leukemia_promyelocytic-HL-60101.1
Leukemialymphoblastic(MOLT-4)33.85
Liver67.8
Lung116.3
Lymphnode37.6
Lymphoma_burkitts(Daudi)184.05
Lymphoma_burkitts(Raji)157.4
MedullaOblongata47.05
OccipitalLobe35.45
OlfactoryBulb38.75
Ovary56.95
Pancreas77.75
PancreaticIslet61.25
ParietalLobe47.2
Pituitary68
Placenta87.75
Pons49.65
PrefrontalCortex22.8
Prostate56.2
Salivarygland48.5
SkeletalMuscle155.4
Skin79.55
SmoothMuscle55.3
Spinalcord39.65
SubthalamicNucleus36.35
SuperiorCervicalGanglion117.8
TemporalLobe41.8
Testis87.85
TestisGermCell103.05
TestisIntersitial71.65
TestisLeydigCell65.35
TestisSeminiferousTubule71.4
Thalamus21.8
Thymus134.9
Thyroid53.95
Tongue63.3
Tonsil45.75
Trachea74.6
TrigeminalGanglion57.85
Uterus42.55
UterusCorpus102.25
WholeBlood35.75
Wholebrain26.05
colon83.05
pineal_day44.26
pineal_night47.68
retina53.7
small_intestine94.45
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P328206
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.95 ± 0.74
Basal Forebrain3.94 ± 0.19
Basal Part of Pons3.81 ± 0.45
Cerebellar Cortex4.3 ± 0.2
Cerebellar Nuclei3.54 ± 0.35
Claustrum4.09 ± 0.93
Epithalamus4.01 ± 0.4
Frontal Lobe3.86 ± 0.54
Globus Pallidus3.78 ± 0.66
Hypothalamus3.8 ± 0.82
Insula3.68 ± 0.52
Limbic Lobe3.75 ± 0.56
Mesencephalon3.83 ± 0.58
Myelencephalon3.81 ± 0.54
Occipital Lobe4.13 ± 0.56
Parietal Lobe3.86 ± 0.49
Pontine Tegmentum3.93 ± 0.62
Striatum3.74 ± 0.49
Subthalamus4 ± 0.26
Temporal Lobe3.75 ± 0.52
Thalamus4.12 ± 0.52
White Matter3.43 ± 1.2
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
DNMBP_HUMAN_1101 18 1101 1118 LVISPLNQLLSMFTGPHK PRIDE
DNMBP_HUMAN_305 15 305 319 VEETMALPQEGSLAR PRIDE
PAp00039738 12 1434 1445 CPSDPDSTSQPR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved