AutismKB 2.0

Annotation Detail for TSPYL4


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Basic Information Top
Gene Symbol:TSPYL4 ( KIAA0721,dJ486I3.2 )
Gene Full Name: TSPY-like 4
Band: 6q22.1
Quick LinksEntrez ID:23270; OMIM: NA; Uniprot ID:TSYL4_HUMAN; ENSEMBL ID: ENSG00000187189; HGNC ID: 21559
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body9 / 70761127
blastocyst2 / 6231932
fetus41 / 56401272
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult49 / 193912125
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor4 / 9417842
cervical tumor0 / 343660 
chondrosarcoma4 / 8282348
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor10 / 26384537
glioma5 / 10688346
head and neck tumor3 / 13630222
kidney tumor3 / 6895943
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia4 / 9725041
normal350 / 3360307104
ovarian tumor1 / 7668213
pancreatic tumor6 / 10461657
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer0 / 1026800 
retinoblastoma1 / 4635621
skin tumor2 / 12494916
soft tissue/muscle tissue tumor5 / 12519139
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone4 / 7165555
bone marrow0 / 488010 
brain277 / 1100989251
cervix0 / 481710 
connective tissue2 / 14925513
ear2 / 16212123
embryonic tissue18 / 21572283
esophagus0 / 202090 
eye9 / 21105442
heart1 / 8962611
intestine2 / 2344728
kidney9 / 21177742
larynx2 / 2414582
liver0 / 2077430 
lung19 / 33697456
lymph0 / 442700 
lymph node4 / 9161043
mammary gland5 / 15327132
mouth1 / 6705214
muscle3 / 10771527
nerve0 / 157680 
ovary1 / 1020519
pancreas11 / 21481251
parathyroid2 / 2053997
pharynx2 / 4132848
pituitary gland2 / 16585120
placenta3 / 28082510
prostate2 / 18934510
salivary gland0 / 201550 
skin10 / 21057447
spleen0 / 539520 
stomach0 / 966190 
testis19 / 33044257
thymus8 / 8113198
thyroid0 / 474730 
tonsil0 / 169990 
trachea5 / 5241395
umbilical cord0 / 136800 
uterus16 / 23287868
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 212928_at
Cell line Expression level Expression bar
721_B_lymphoblasts24.05
Adipocyte9.5
AdrenalCortex18.7
Adrenalgland41.45
Amygdala467.9
Appendix15.05
AtrioventricularNode9.05
BDCA4+_DentriticCells19.9
Bonemarrow9.95
BronchialEpithelialCells9.85
CD105+_Endothelial26.8
CD14+_Monocytes9.85
CD19+_BCells(neg._sel.)35.65
CD33+_Myeloid24.75
CD34+56.05
CD4+_Tcells22.1
CD56+_NKCells31.55
CD71+_EarlyErythroid7.25
CD8+_Tcells24.15
CardiacMyocytes15
Caudatenucleus159.4
Cerebellum235.05
CerebellumPeduncles172.7
CiliaryGanglion6.05
CingulateCortex132.2
Colorectaladenocarcinoma12.25
DorsalRootGanglion12.1
FetalThyroid16.35
Fetalbrain215.35
Fetalliver14.4
Fetallung15.45
GlobusPallidus60.4
Heart17.25
Hypothalamus290.4
Kidney12.15
Leukemia_chronicMyelogenousK-56213.7
Leukemia_promyelocytic-HL-607.2
Leukemialymphoblastic(MOLT-4)16.75
Liver11.6
Lung18.45
Lymphnode12.6
Lymphoma_burkitts(Daudi)10.25
Lymphoma_burkitts(Raji)12
MedullaOblongata140
OccipitalLobe199.1
OlfactoryBulb25
Ovary6.15
Pancreas6.85
PancreaticIslet22.2
ParietalLobe109.5
Pituitary101.25
Placenta16.05
Pons76.4
PrefrontalCortex388.6
Prostate69.95
Salivarygland10.45
SkeletalMuscle9.95
Skin9.15
SmoothMuscle14.8
Spinalcord99.15
SubthalamicNucleus121
SuperiorCervicalGanglion20.9
TemporalLobe88
Testis27.7
TestisGermCell18.7
TestisIntersitial10.6
TestisLeydigCell15.75
TestisSeminiferousTubule14.3
Thalamus108.25
Thymus28.35
Thyroid32.05
Tongue8.2
Tonsil10.7
Trachea14.65
TrigeminalGanglion17.1
Uterus30.5
UterusCorpus14.7
WholeBlood10.95
Wholebrain332.55
colon17.2
pineal_day98.72
pineal_night122.1
retina127.325
small_intestine23.45
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_2036_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.55 ± 0.57
Basal Forebrain6.52 ± 0.25
Basal Part of Pons6.9 ± 0.24
Cerebellar Cortex6.96 ± 0.18
Cerebellar Nuclei6.6 ± 0.35
Claustrum6.68 ± 0.4
Epithalamus6.61 ± 0.41
Frontal Lobe6.72 ± 0.39
Globus Pallidus5.58 ± 0.68
Hypothalamus7.03 ± 0.51
Insula6.79 ± 0.26
Limbic Lobe6.69 ± 0.62
Mesencephalon6.62 ± 0.58
Myelencephalon6.63 ± 0.53
Occipital Lobe6.65 ± 0.51
Parietal Lobe6.95 ± 0.3
Pontine Tegmentum6.72 ± 0.52
Striatum5.88 ± 0.49
Subthalamus7.02 ± 0.35
Temporal Lobe6.8 ± 0.34
Thalamus6.63 ± 0.43
White Matter5.64 ± 0.57
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Tspyl4CBCerebellum100
100
Tspyl4CTXCerebral cortex100
100
Tspyl4HIPHippocampal region100
100
Tspyl4HPFHippocampal formation100
100
Tspyl4HYHypothalamus100
100
Tspyl4LSXLateral septal complex100
100
Tspyl4MBMidbrain100
100
Tspyl4MYMedulla100
100
Tspyl4OLFOlfactory bulb100
100
Tspyl4PPons100
100
Tspyl4PALPallidum100
100
Tspyl4RHPRetrohippocampal region100
100
Tspyl4sAMYStriatum-like amygdalar nuclei100
100
Tspyl4STRStriatum100
100
Tspyl4STRdStriatum dorsal region100
100
Tspyl4STRvStriatum ventral region100
100
Tspyl4THThalamus100
100
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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