AutismKB 2.0

Annotation Detail for KIAA0664


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Basic Information Top
Gene Symbol:KIAA0664 ( CLU1,DKFZp686L05242,DKFZp686M09233,FLJ23672 )
Gene Full Name: KIAA0664
Band: 17p13.3
Quick LinksEntrez ID:23277; OMIM: NA; Uniprot ID:K0664_HUMAN; ENSEMBL ID: ENSG00000132361; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst4 / 6231964
fetus13 / 56401223
neonate2 / 3109764
infant1 / 2362042
juvenile3 / 5555653
adult117 / 193912160
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor10 / 94178106
cervical tumor1 / 3436629
chondrosarcoma10 / 82823120
colorectal tumor9 / 11424678
esophageal tumor2 / 17290115
gastrointestinal tumor12 / 119369100
germ cell tumor17 / 26384564
glioma5 / 10688346
head and neck tumor11 / 13630280
kidney tumor1 / 6895914
leukemia6 / 9584262
liver tumor4 / 9635941
lung tumor5 / 10312748
lymphoma10 / 71755139
non-neoplasia3 / 9725030
normal124 / 336030736
ovarian tumor8 / 76682104
pancreatic tumor6 / 10461657
primitive neuroectodermal tumor of the CNS6 / 12568047
prostate cancer6 / 10268058
retinoblastoma2 / 4635643
skin tumor13 / 124949104
soft tissue/muscle tissue tumor8 / 12519163
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland0 / 331970 
ascites10 / 40015249
bladder2 / 2975767
blood2 / 12347816
bone8 / 71655111
bone marrow2 / 4880140
brain43 / 110098939
cervix3 / 4817162
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue10 / 21572246
esophagus2 / 2020998
eye17 / 21105480
heart1 / 8962611
intestine19 / 23447281
kidney12 / 21177756
larynx0 / 241450 
liver7 / 20774333
lung14 / 33697441
lymph6 / 44270135
lymph node7 / 9161076
mammary gland11 / 15327171
mouth10 / 67052149
muscle7 / 10771564
nerve2 / 15768126
ovary8 / 10205178
pancreas9 / 21481241
parathyroid2 / 2053997
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta10 / 28082535
prostate9 / 18934547
salivary gland0 / 201550 
skin15 / 21057471
spleen2 / 5395237
stomach1 / 9661910
testis15 / 33044245
thymus3 / 8113136
thyroid1 / 4747321
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord2 / 13680146
uterus16 / 23287868
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 212456_at
Cell line Expression level Expression bar
721_B_lymphoblasts367.8
Adipocyte58.7
AdrenalCortex105
Adrenalgland75.35
Amygdala53.75
Appendix26.1
AtrioventricularNode7.35
BDCA4+_DentriticCells60.35
Bonemarrow50.15
BronchialEpithelialCells53.8
CD105+_Endothelial393.7
CD14+_Monocytes52.85
CD19+_BCells(neg._sel.)54.25
CD33+_Myeloid90.4
CD34+262.75
CD4+_Tcells66.15
CD56+_NKCells65.4
CD71+_EarlyErythroid47.75
CD8+_Tcells62.1
CardiacMyocytes53.45
Caudatenucleus45.45
Cerebellum45.95
CerebellumPeduncles58.05
CiliaryGanglion25.05
CingulateCortex66.15
Colorectaladenocarcinoma73.3
DorsalRootGanglion10.55
FetalThyroid63.6
Fetalbrain51.3
Fetalliver54.75
Fetallung44.1
GlobusPallidus35.4
Heart242.45
Hypothalamus55.8
Kidney67.1
Leukemia_chronicMyelogenousK-56251.25
Leukemia_promyelocytic-HL-60107.15
Leukemialymphoblastic(MOLT-4)41.25
Liver277.55
Lung91.85
Lymphnode44.45
Lymphoma_burkitts(Daudi)110.15
Lymphoma_burkitts(Raji)88.3
MedullaOblongata46.45
OccipitalLobe45.95
OlfactoryBulb24.25
Ovary19.25
Pancreas74.2
PancreaticIslet58.2
ParietalLobe53.8
Pituitary55.95
Placenta44.8
Pons48.15
PrefrontalCortex58.05
Prostate106.95
Salivarygland40.7
SkeletalMuscle108.9
Skin37.1
SmoothMuscle30.25
Spinalcord53.95
SubthalamicNucleus51.95
SuperiorCervicalGanglion40.2
TemporalLobe58.3
Testis70.05
TestisGermCell52.15
TestisIntersitial42.35
TestisLeydigCell49.3
TestisSeminiferousTubule47.5
Thalamus55.15
Thymus34
Thyroid64.15
Tongue66.05
Tonsil48.4
Trachea48.1
TrigeminalGanglion45.35
Uterus36.7
UterusCorpus44.6
WholeBlood50.9
Wholebrain58.6
colon65.5
pineal_day67.42
pineal_night73.48
retina61.35
small_intestine49.5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P4435
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.75 ± 0.4
Basal Forebrain5.49 ± 0.2
Basal Part of Pons5.81 ± 0.29
Cerebellar Cortex5.57 ± 0.32
Cerebellar Nuclei5.57 ± 0.56
Claustrum5.98 ± 0.61
Epithalamus5.1 ± 0.41
Frontal Lobe5.59 ± 0.34
Globus Pallidus5.72 ± 0.33
Hypothalamus5.5 ± 0.28
Insula5.57 ± 0.31
Limbic Lobe5.84 ± 0.37
Mesencephalon5.62 ± 0.44
Myelencephalon5.73 ± 0.38
Occipital Lobe5.88 ± 0.39
Parietal Lobe5.67 ± 0.35
Pontine Tegmentum5.57 ± 0.35
Striatum5.73 ± 0.43
Subthalamus5.47 ± 0.46
Temporal Lobe5.64 ± 0.37
Thalamus5.75 ± 0.34
White Matter5.47 ± 0.23
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
1300001I01RikCBCerebellum52.4
88.04
1300001I01RikCTXCerebral cortex83.34
69.27
1300001I01RikHIPHippocampal region52.43
81.75
1300001I01RikHPFHippocampal formation62.73
76.24
1300001I01RikHYHypothalamus62.08
52.69
1300001I01RikLSXLateral septal complex74.67
57.23
1300001I01RikMBMidbrain57.22
56.28
1300001I01RikMYMedulla74.76
86.43
1300001I01RikOLFOlfactory bulb73.68
70.15
1300001I01RikPPons61.83
71.86
1300001I01RikPALPallidum59.78
57
1300001I01RikRHPRetrohippocampal region79.22
70.9
1300001I01RiksAMYStriatum-like amygdalar nuclei50.57
40.77
1300001I01RikSTRStriatum56.2
43.47
1300001I01RikSTRdStriatum dorsal region51.63
40.05
1300001I01RikSTRvStriatum ventral region70.37
52.19
1300001I01RikTHThalamus68.55
61.52
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
K0664_HUMAN_106 12 106 117 SVEGLQEGSVLR PRIDE
K0664_HUMAN_431 11 431 441 QELVDAFVEHR PRIDE
K0664_HUMAN_606 11 606 616 QELVDAFVEHR PRIDE
PAp00025854 23 313 335 IATPFQVYSWTAPQAEHAMDCVR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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