AutismKB 2.0

Annotation Detail for MGRN1


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Basic Information Top
Gene Symbol:MGRN1 ( KIAA0544,RNF156 )
Gene Full Name: mahogunin, ring finger 1
Band: 16p13.3
Quick LinksEntrez ID:23295; OMIM: 607559; Uniprot ID:MGRN1_HUMAN; ENSEMBL ID: ENSG00000102858; HGNC ID: 20254
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body8 / 70761113
blastocyst5 / 6231980
fetus14 / 56401224
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult86 / 193912144
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor8 / 9417884
cervical tumor0 / 343660 
chondrosarcoma7 / 8282384
colorectal tumor6 / 11424652
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor11 / 26384541
glioma6 / 10688356
head and neck tumor9 / 13630266
kidney tumor9 / 68959130
leukemia2 / 9584220
liver tumor7 / 9635972
lung tumor11 / 103127106
lymphoma1 / 7175513
non-neoplasia1 / 9725010
normal122 / 336030736
ovarian tumor1 / 7668213
pancreatic tumor11 / 104616105
primitive neuroectodermal tumor of the CNS5 / 12568039
prostate cancer1 / 1026809
retinoblastoma6 / 46356129
skin tumor9 / 12494972
soft tissue/muscle tissue tumor5 / 12519139
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood3 / 12347824
bone1 / 7165513
bone marrow3 / 4880161
brain51 / 110098946
cervix0 / 481710 
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue18 / 21572283
esophagus0 / 202090 
eye18 / 21105485
heart1 / 8962611
intestine11 / 23447246
kidney11 / 21177751
larynx1 / 2414541
liver9 / 20774343
lung23 / 33697468
lymph1 / 4427022
lymph node2 / 9161021
mammary gland13 / 15327184
mouth1 / 6705214
muscle0 / 1077150 
nerve2 / 15768126
ovary2 / 10205119
pancreas17 / 21481279
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta11 / 28082539
prostate2 / 18934510
salivary gland6 / 20155297
skin12 / 21057456
spleen2 / 5395237
stomach1 / 9661910
testis9 / 33044227
thymus3 / 8113136
thyroid1 / 4747321
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus7 / 23287830
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 212576_at
Cell line Expression level Expression bar
721_B_lymphoblasts94.05
Adipocyte7.6
AdrenalCortex11.7
Adrenalgland9.75
Amygdala24.7
Appendix5.4
AtrioventricularNode6.05
BDCA4+_DentriticCells87.4
Bonemarrow10.85
BronchialEpithelialCells7.5
CD105+_Endothelial20.6
CD14+_Monocytes91.85
CD19+_BCells(neg._sel.)45.25
CD33+_Myeloid121.2
CD34+118.55
CD4+_Tcells33.25
CD56+_NKCells108.6
CD71+_EarlyErythroid9.55
CD8+_Tcells30.45
CardiacMyocytes10.3
Caudatenucleus15.65
Cerebellum9.45
CerebellumPeduncles25.65
CiliaryGanglion2.6
CingulateCortex16.4
Colorectaladenocarcinoma9.3
DorsalRootGanglion4.55
FetalThyroid19
Fetalbrain43.85
Fetalliver2.7
Fetallung11.65
GlobusPallidus8.5
Heart9.45
Hypothalamus21.3
Kidney6.25
Leukemia_chronicMyelogenousK-5627.85
Leukemia_promyelocytic-HL-609.8
Leukemialymphoblastic(MOLT-4)9.4
Liver38.85
Lung59.7
Lymphnode8.7
Lymphoma_burkitts(Daudi)11.65
Lymphoma_burkitts(Raji)20
MedullaOblongata11.35
OccipitalLobe23.95
OlfactoryBulb6.25
Ovary4.25
Pancreas7.3
PancreaticIslet12.4
ParietalLobe20.05
Pituitary12
Placenta24.3
Pons10.75
PrefrontalCortex46.9
Prostate38.1
Salivarygland6.3
SkeletalMuscle7.6
Skin3.95
SmoothMuscle18.75
Spinalcord11.9
SubthalamicNucleus10.95
SuperiorCervicalGanglion4.1
TemporalLobe10.6
Testis6.55
TestisGermCell8.25
TestisIntersitial5.8
TestisLeydigCell3.7
TestisSeminiferousTubule6.5
Thalamus11.6
Thymus15.15
Thyroid22.25
Tongue7.35
Tonsil9.3
Trachea5.1
TrigeminalGanglion7.35
Uterus21
UterusCorpus7.8
WholeBlood30.85
Wholebrain30.3
colon8.35
pineal_day27.7
pineal_night20.96
retina24.65
small_intestine10.6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P355824
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala10.53 ± 0.37
Basal Forebrain10.28 ± 0.18
Basal Part of Pons10.8 ± 0.16
Cerebellar Cortex10.65 ± 0.3
Cerebellar Nuclei10.27 ± 0.45
Claustrum10.54 ± 0.22
Epithalamus10.19 ± 0.37
Frontal Lobe10.63 ± 0.32
Globus Pallidus9.72 ± 0.15
Hypothalamus10.28 ± 0.32
Insula10.76 ± 0.19
Limbic Lobe10.7 ± 0.36
Mesencephalon10.3 ± 0.22
Myelencephalon10.48 ± 0.3
Occipital Lobe10.39 ± 0.36
Parietal Lobe10.56 ± 0.28
Pontine Tegmentum10.42 ± 0.27
Striatum10.21 ± 0.37
Subthalamus10.47 ± 0.03
Temporal Lobe10.66 ± 0.26
Thalamus10.33 ± 0.22
White Matter10.45 ± 0.28
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Mgrn1CBCerebellum43.83
82.04
Mgrn1CTXCerebral cortex100
100
Mgrn1HIPHippocampal region85.07
100
Mgrn1HPFHippocampal formation99.72
100
Mgrn1HYHypothalamus93.47
86.39
Mgrn1LSXLateral septal complex100
91.69
Mgrn1MBMidbrain100
100
Mgrn1MYMedulla96.41
100
Mgrn1OLFOlfactory bulb100
100
Mgrn1PPons88.89
100
Mgrn1PALPallidum91.82
100
Mgrn1RHPRetrohippocampal region100
100
Mgrn1sAMYStriatum-like amygdalar nuclei100
100
Mgrn1STRStriatum95.06
80.77
Mgrn1STRdStriatum dorsal region90.47
75.9
Mgrn1STRvStriatum ventral region100
85.84
Mgrn1THThalamus89.61
90.01
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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