AutismKB 2.0

Annotation Detail for SATB2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:SATB2 ( FLJ21474,FLJ32076,KIAA1034,MGC119474,MGC119477 )
Gene Full Name: SATB homeobox 2
Band: 2q33.1
Quick LinksEntrez ID:23314; OMIM: 608148; Uniprot ID:SATB2_HUMAN; ENSEMBL ID: ENSG00000119042; HGNC ID: 21637
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst0 / 623190 
fetus37 / 56401265
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult25 / 193912112
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor7 / 11424661
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia2 / 9584220
liver tumor9 / 9635993
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal80 / 336030723
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone2 / 7165527
bone marrow0 / 488010 
brain47 / 110098942
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye2 / 2110549
heart0 / 896260 
intestine8 / 23447234
kidney0 / 2117770 
larynx0 / 241450 
liver10 / 20774348
lung1 / 3369742
lymph0 / 442700 
lymph node1 / 9161010
mammary gland0 / 1532710 
mouth0 / 670520 
muscle3 / 10771527
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin1 / 2105744
spleen0 / 539520 
stomach0 / 966190 
testis5 / 33044215
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 213435_at
Cell line Expression level Expression bar
721_B_lymphoblasts4.95
Adipocyte4
AdrenalCortex4.35
Adrenalgland3.4
Amygdala4.75
Appendix4.05
AtrioventricularNode3.15
BDCA4+_DentriticCells4.45
Bonemarrow3.9
BronchialEpithelialCells3.95
CD105+_Endothelial4.1
CD14+_Monocytes4.3
CD19+_BCells(neg._sel.)4.25
CD33+_Myeloid6.85
CD34+5.45
CD4+_Tcells4.35
CD56+_NKCells4.8
CD71+_EarlyErythroid3.75
CD8+_Tcells3.85
CardiacMyocytes5.15
Caudatenucleus3.6
Cerebellum3.25
CerebellumPeduncles4.55
CiliaryGanglion2.9
CingulateCortex33
Colorectaladenocarcinoma4.1
DorsalRootGanglion3.1
FetalThyroid3.9
Fetalbrain1341.75
Fetalliver3.45
Fetallung3.3
GlobusPallidus16.3
Heart5.1
Hypothalamus4.35
Kidney3.25
Leukemia_chronicMyelogenousK-56234.05
Leukemia_promyelocytic-HL-603.55
Leukemialymphoblastic(MOLT-4)3.25
Liver5.3
Lung4.4
Lymphnode3.4
Lymphoma_burkitts(Daudi)5.15
Lymphoma_burkitts(Raji)5.65
MedullaOblongata25.05
OccipitalLobe52.8
OlfactoryBulb3.2
Ovary2.7
Pancreas3.2
PancreaticIslet4.25
ParietalLobe13.5
Pituitary4.65
Placenta4.15
Pons5.25
PrefrontalCortex205.4
Prostate4.65
Salivarygland3.55
SkeletalMuscle4.65
Skin3.1
SmoothMuscle4.55
Spinalcord4.3
SubthalamicNucleus38.25
SuperiorCervicalGanglion4.65
TemporalLobe22.9
Testis3.5
TestisGermCell3.35
TestisIntersitial3.4
TestisLeydigCell4
TestisSeminiferousTubule3.45
Thalamus4.1
Thymus3.15
Thyroid5.05
Tongue4
Tonsil3.9
Trachea3.35
TrigeminalGanglion4.05
Uterus3.25
UterusCorpus3.65
WholeBlood4.4
Wholebrain100.8
colon214.85
pineal_day5.04
pineal_night4.92
retina4.85
small_intestine3.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_4775_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.81 ± 0.85
Basal Forebrain5.58 ± 0.62
Basal Part of Pons5.82 ± 0.73
Cerebellar Cortex4.88 ± 0.6
Cerebellar Nuclei5.1 ± 0.71
Claustrum7.66 ± 0.63
Epithalamus5.54 ± 0.67
Frontal Lobe6.01 ± 0.71
Globus Pallidus4.5 ± 1.92
Hypothalamus5.17 ± 0.44
Insula6.29 ± 0.56
Limbic Lobe5.99 ± 1.02
Mesencephalon5.83 ± 0.89
Myelencephalon5.88 ± 0.9
Occipital Lobe6.43 ± 0.54
Parietal Lobe6.52 ± 0.72
Pontine Tegmentum5.9 ± 0.86
Striatum4.99 ± 1.6
Subthalamus4.97 ± 0.78
Temporal Lobe6.19 ± 0.61
Thalamus5.94 ± 0.66
White Matter5.74 ± 0.6
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Satb2CBCerebellum10.92
14.56
Satb2CTXCerebral cortex100
100
Satb2HIPHippocampal region18.04
29.5
Satb2HPFHippocampal formation42.95
54.09
Satb2HYHypothalamus5.49
4.28
Satb2LSXLateral septal complex2.52
2.57
Satb2MBMidbrain5.41
6.17
Satb2MYMedulla7.15
7.97
Satb2OLFOlfactory bulb20.06
17.45
Satb2PPons5.85
6.04
Satb2PALPallidum5.07
4.83
Satb2RHPRetrohippocampal region77.69
79.23
Satb2sAMYStriatum-like amygdalar nuclei8.41
6.54
Satb2STRStriatum7.46
8.58
Satb2STRdStriatum dorsal region8.25
10.6
Satb2STRvStriatum ventral region5.36
4.76
Satb2THThalamus4.51
3.65
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00073330 22 326 347 LLAHQHPQAINQQFLNHPPIPR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018