AutismKB 2.0

Annotation Detail for TRIM2


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Basic Information Top
Gene Symbol:TRIM2 ( KIAA0517,RNF86 )
Gene Full Name: tripartite motif-containing 2
Band: 4q31.3
Quick LinksEntrez ID:23321; OMIM: NA; Uniprot ID:TRIM2_HUMAN; ENSEMBL ID: ENSG00000109654; HGNC ID: 15974
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body5 / 7076170
blastocyst7 / 62319112
fetus66 / 564012117
neonate1 / 3109732
infant0 / 236200 
juvenile0 / 555560 
adult91 / 193912146
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor11 / 11424696
esophageal tumor1 / 1729057
gastrointestinal tumor2 / 11936916
germ cell tumor9 / 26384534
glioma7 / 10688365
head and neck tumor7 / 13630251
kidney tumor6 / 6895987
leukemia1 / 9584210
liver tumor3 / 9635931
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia10 / 97250102
normal265 / 336030778
ovarian tumor1 / 7668213
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor11 / 12494988
soft tissue/muscle tissue tumor8 / 12519163
uterine tumor7 / 9025777
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder1 / 2975733
blood1 / 1234788
bone1 / 7165513
bone marrow1 / 4880120
brain179 / 1100989162
cervix0 / 481710 
connective tissue2 / 14925513
ear1 / 1621261
embryonic tissue18 / 21572283
esophagus1 / 2020949
eye9 / 21105442
heart9 / 89626100
intestine18 / 23447276
kidney18 / 21177784
larynx0 / 241450 
liver5 / 20774324
lung18 / 33697453
lymph0 / 442700 
lymph node0 / 916100 
mammary gland11 / 15327171
mouth2 / 6705229
muscle8 / 10771574
nerve2 / 15768126
ovary2 / 10205119
pancreas9 / 21481241
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland2 / 16585120
placenta3 / 28082510
prostate4 / 18934521
salivary gland1 / 2015549
skin12 / 21057456
spleen1 / 5395218
stomach4 / 9661941
testis12 / 33044236
thymus1 / 8113112
thyroid5 / 47473105
tonsil0 / 169990 
trachea5 / 5241395
umbilical cord0 / 136800 
uterus13 / 23287855
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 215945_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts15.8
Adipocyte20.85
AdrenalCortex18.25
Adrenalgland17.5
Amygdala69.9
Appendix16
AtrioventricularNode15.2
BDCA4+_DentriticCells11.5
Bonemarrow16.85
BronchialEpithelialCells12.45
CD105+_Endothelial16.4
CD14+_Monocytes10.6
CD19+_BCells(neg._sel.)15.1
CD33+_Myeloid16.3
CD34+14.85
CD4+_Tcells14.65
CD56+_NKCells14.5
CD71+_EarlyErythroid15.05
CD8+_Tcells11
CardiacMyocytes18.8
Caudatenucleus34.8
Cerebellum58
CerebellumPeduncles252.7
CiliaryGanglion12.75
CingulateCortex303.05
Colorectaladenocarcinoma17.4
DorsalRootGanglion29.75
FetalThyroid30.95
Fetalbrain50.6
Fetalliver14.15
Fetallung14.3
GlobusPallidus181.1
Heart17.95
Hypothalamus153.3
Kidney14.2
Leukemia_chronicMyelogenousK-56214.1
Leukemia_promyelocytic-HL-6013.9
Leukemialymphoblastic(MOLT-4)12.05
Liver19.3
Lung14.1
Lymphnode13.35
Lymphoma_burkitts(Daudi)20.7
Lymphoma_burkitts(Raji)17.15
MedullaOblongata328.6
OccipitalLobe614.25
OlfactoryBulb42.85
Ovary11.3
Pancreas25.1
PancreaticIslet29.65
ParietalLobe531.4
Pituitary40.15
Placenta13.9
Pons183.2
PrefrontalCortex152.35
Prostate16.95
Salivarygland22.75
SkeletalMuscle14.8
Skin13.7
SmoothMuscle16.55
Spinalcord39.65
SubthalamicNucleus214.35
SuperiorCervicalGanglion15.15
TemporalLobe97.4
Testis13.15
TestisGermCell10.4
TestisIntersitial9.65
TestisLeydigCell16.25
TestisSeminiferousTubule13.75
Thalamus92.8
Thymus9
Thyroid24.05
Tongue16.6
Tonsil14
Trachea24.65
TrigeminalGanglion17.8
Uterus12.45
UterusCorpus14.45
WholeBlood11.25
Wholebrain82.15
colon146.7
pineal_day322.28
pineal_night317.54
retina196.825
small_intestine28.7
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P213141
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala12.52 ± 0.23
Basal Forebrain12.59 ± 0.26
Basal Part of Pons12.87 ± 0.2
Cerebellar Cortex12.64 ± 0.14
Cerebellar Nuclei12.77 ± 0.17
Claustrum12.74 ± 0.35
Epithalamus12.58 ± 0.16
Frontal Lobe12.76 ± 0.27
Globus Pallidus12.97 ± 0.18
Hypothalamus12.58 ± 0.15
Insula12.5 ± 0.15
Limbic Lobe12.86 ± 0.26
Mesencephalon12.67 ± 0.26
Myelencephalon12.69 ± 0.24
Occipital Lobe12.86 ± 0.21
Parietal Lobe12.7 ± 0.21
Pontine Tegmentum12.66 ± 0.22
Striatum12.4 ± 0.31
Subthalamus12.76 ± 0.31
Temporal Lobe12.59 ± 0.19
Thalamus12.62 ± 0.22
White Matter13.88 ± 0.17
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Trim2CBCerebellum59.27
100
Trim2CTXCerebral cortex100
100
Trim2HIPHippocampal region100
100
Trim2HPFHippocampal formation100
100
Trim2HYHypothalamus100
100
Trim2LSXLateral septal complex100
100
Trim2MBMidbrain100
100
Trim2MYMedulla100
100
Trim2OLFOlfactory bulb100
100
Trim2PPons94.09
100
Trim2PALPallidum100
100
Trim2RHPRetrohippocampal region100
100
Trim2sAMYStriatum-like amygdalar nuclei100
100
Trim2STRStriatum100
100
Trim2STRdStriatum dorsal region100
100
Trim2STRvStriatum ventral region100
100
Trim2THThalamus99.34
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00077148 22 280 301 SCSNFTAQALNHGTETEVLLVK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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