AutismKB 2.0

Annotation Detail for TTC28


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Basic Information Top
Gene Symbol:TTC28 ( KIAA1043 )
Gene Full Name: tetratricopeptide repeat domain 28
Band: 22q12.1
Quick LinksEntrez ID:23331; OMIM: NA; Uniprot ID:TTC28_HUMAN; ENSEMBL ID: ENSG00000100154; HGNC ID: 29179
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst1 / 6231916
fetus47 / 56401283
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult48 / 193912124
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma4 / 17475228
breast (mammary gland) tumor3 / 9417831
cervical tumor1 / 3436629
chondrosarcoma2 / 8282324
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor4 / 26384515
glioma2 / 10688318
head and neck tumor2 / 13630214
kidney tumor1 / 6895914
leukemia1 / 9584210
liver tumor3 / 9635931
lung tumor2 / 10312719
lymphoma3 / 7175541
non-neoplasia6 / 9725061
normal126 / 336030737
ovarian tumor4 / 7668252
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS10 / 12568079
prostate cancer0 / 1026800 
retinoblastoma1 / 4635621
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor5 / 12519139
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder2 / 2975767
blood2 / 12347816
bone3 / 7165541
bone marrow0 / 488010 
brain38 / 110098934
cervix1 / 4817120
connective tissue4 / 14925526
ear2 / 16212123
embryonic tissue12 / 21572255
esophagus0 / 202090 
eye7 / 21105433
heart5 / 8962655
intestine2 / 2344728
kidney3 / 21177714
larynx2 / 2414582
liver5 / 20774324
lung10 / 33697429
lymph0 / 442700 
lymph node4 / 9161043
mammary gland3 / 15327119
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary5 / 10205148
pancreas8 / 21481237
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland1 / 1658560
placenta1 / 2808253
prostate2 / 18934510
salivary gland0 / 201550 
skin3 / 21057414
spleen5 / 5395292
stomach0 / 966190 
testis12 / 33044236
thymus0 / 811310 
thyroid2 / 4747342
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus16 / 23287868
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 215146_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts9.85
Adipocyte11.3
AdrenalCortex12.85
Adrenalgland20.1
Amygdala12.85
Appendix21.95
AtrioventricularNode10.85
BDCA4+_DentriticCells11.5
Bonemarrow10
BronchialEpithelialCells7.3
CD105+_Endothelial9.25
CD14+_Monocytes10.45
CD19+_BCells(neg._sel.)11.6
CD33+_Myeloid11.2
CD34+14.85
CD4+_Tcells9.5
CD56+_NKCells9.95
CD71+_EarlyErythroid8.75
CD8+_Tcells7.95
CardiacMyocytes15.55
Caudatenucleus8.35
Cerebellum7.35
CerebellumPeduncles11.35
CiliaryGanglion12.6
CingulateCortex10.75
Colorectaladenocarcinoma7.85
DorsalRootGanglion10.45
FetalThyroid10.55
Fetalbrain111.05
Fetalliver8.35
Fetallung8.25
GlobusPallidus7.65
Heart16
Hypothalamus10.05
Kidney9.05
Leukemia_chronicMyelogenousK-5628.5
Leukemia_promyelocytic-HL-608.35
Leukemialymphoblastic(MOLT-4)6.9
Liver14.1
Lung88
Lymphnode7.45
Lymphoma_burkitts(Daudi)11.9
Lymphoma_burkitts(Raji)14.1
MedullaOblongata8.4
OccipitalLobe8.25
OlfactoryBulb10.8
Ovary7.1
Pancreas8.15
PancreaticIslet10.7
ParietalLobe10.05
Pituitary11.3
Placenta20.05
Pons10.1
PrefrontalCortex12.15
Prostate78
Salivarygland8.4
SkeletalMuscle13.85
Skin9.8
SmoothMuscle11.05
Spinalcord20.4
SubthalamicNucleus10.5
SuperiorCervicalGanglion17.95
TemporalLobe8.5
Testis10.15
TestisGermCell9.2
TestisIntersitial10.4
TestisLeydigCell9.9
TestisSeminiferousTubule8.4
Thalamus9.65
Thymus8.45
Thyroid83.3
Tongue10.25
Tonsil9.1
Trachea8.1
TrigeminalGanglion14.35
Uterus112.8
UterusCorpus21.05
WholeBlood9.55
Wholebrain15.05
colon18.1
pineal_day14.8
pineal_night15.08
retina58.425
small_intestine20.65
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P29185
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.59 ± 0.38
Basal Forebrain6.59 ± 0.12
Basal Part of Pons6.06 ± 0.3
Cerebellar Cortex5.89 ± 0.21
Cerebellar Nuclei6.06 ± 0.25
Claustrum6.84 ± 0.51
Epithalamus6.39 ± 0.38
Frontal Lobe6.04 ± 0.39
Globus Pallidus6.51 ± 0.34
Hypothalamus6.25 ± 0.32
Insula6.3 ± 0.4
Limbic Lobe6.33 ± 0.61
Mesencephalon6.39 ± 0.44
Myelencephalon6.3 ± 0.41
Occipital Lobe6.8 ± 0.56
Parietal Lobe6.28 ± 0.35
Pontine Tegmentum6.24 ± 0.46
Striatum6.62 ± 0.37
Subthalamus5.97 ± 0.27
Temporal Lobe6.32 ± 0.37
Thalamus6.04 ± 0.3
White Matter7.07 ± 0.52
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00515923 21 2128 2148 LASSDTGESDQSSTETDSTVK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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