AutismKB 2.0

Annotation Detail for PHF15


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Basic Information Top
Gene Symbol:PHF15 ( JADE2,KIAA0239 )
Gene Full Name: PHD finger protein 15
Band: 5q31.1
Quick LinksEntrez ID:23338; OMIM: 610515; Uniprot ID:JADE2_HUMAN; ENSEMBL ID: ENSG00000043143; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst0 / 623190 
fetus5 / 5640128
neonate2 / 3109764
infant0 / 236200 
juvenile0 / 555560 
adult103 / 193912153
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma10 / 82823120
colorectal tumor12 / 114246105
esophageal tumor0 / 172900 
gastrointestinal tumor7 / 11936958
germ cell tumor10 / 26384537
glioma8 / 10688374
head and neck tumor26 / 136302190
kidney tumor1 / 6895914
leukemia5 / 9584252
liver tumor1 / 9635910
lung tumor2 / 10312719
lymphoma5 / 7175569
non-neoplasia2 / 9725020
normal85 / 336030725
ovarian tumor4 / 7668252
pancreatic tumor6 / 10461657
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer3 / 10268029
retinoblastoma0 / 463560 
skin tumor14 / 124949112
soft tissue/muscle tissue tumor6 / 12519147
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites1 / 4001524
bladder1 / 2975733
blood5 / 12347840
bone7 / 7165597
bone marrow0 / 488010 
brain22 / 110098919
cervix1 / 4817120
connective tissue7 / 14925546
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye7 / 21105433
heart0 / 896260 
intestine17 / 23447272
kidney4 / 21177718
larynx21 / 24145869
liver5 / 20774324
lung8 / 33697423
lymph4 / 4427090
lymph node16 / 91610174
mammary gland1 / 1532716
mouth4 / 6705259
muscle1 / 1077159
nerve1 / 1576863
ovary5 / 10205148
pancreas11 / 21481251
parathyroid2 / 2053997
pharynx1 / 4132824
pituitary gland1 / 1658560
placenta4 / 28082514
prostate6 / 18934531
salivary gland1 / 2015549
skin15 / 21057471
spleen1 / 5395218
stomach7 / 9661972
testis6 / 33044218
thymus9 / 81131110
thyroid2 / 4747342
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus11 / 23287847
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 212660_at
Cell line Expression level Expression bar
721_B_lymphoblasts40.7
Adipocyte21.6
AdrenalCortex24.45
Adrenalgland52.9
Amygdala30.15
Appendix9.5
AtrioventricularNode5.55
BDCA4+_DentriticCells23.45
Bonemarrow13.35
BronchialEpithelialCells10.25
CD105+_Endothelial18.1
CD14+_Monocytes21.1
CD19+_BCells(neg._sel.)178.6
CD33+_Myeloid22.55
CD34+52.45
CD4+_Tcells218.4
CD56+_NKCells237.9
CD71+_EarlyErythroid8.3
CD8+_Tcells244.35
CardiacMyocytes8.65
Caudatenucleus20.85
Cerebellum46.5
CerebellumPeduncles55.15
CiliaryGanglion6.45
CingulateCortex26.15
Colorectaladenocarcinoma42.65
DorsalRootGanglion7.65
FetalThyroid18.1
Fetalbrain10.45
Fetalliver15.2
Fetallung11.1
GlobusPallidus14.55
Heart18.65
Hypothalamus53.15
Kidney16.1
Leukemia_chronicMyelogenousK-5627.05
Leukemia_promyelocytic-HL-6014.7
Leukemialymphoblastic(MOLT-4)17.2
Liver18.9
Lung46.25
Lymphnode31.8
Lymphoma_burkitts(Daudi)43.15
Lymphoma_burkitts(Raji)12.55
MedullaOblongata38.35
OccipitalLobe26.35
OlfactoryBulb16.1
Ovary3.65
Pancreas16.25
PancreaticIslet25.2
ParietalLobe23.7
Pituitary42.4
Placenta19.8
Pons19.2
PrefrontalCortex71.75
Prostate28.1
Salivarygland14.4
SkeletalMuscle18.1
Skin10.65
SmoothMuscle22.8
Spinalcord23.8
SubthalamicNucleus20.2
SuperiorCervicalGanglion16.6
TemporalLobe18.5
Testis17.55
TestisGermCell11.75
TestisIntersitial4.35
TestisLeydigCell8.75
TestisSeminiferousTubule7.5
Thalamus20.7
Thymus31.3
Thyroid26.3
Tongue18.25
Tonsil19.65
Trachea12.5
TrigeminalGanglion12.4
Uterus28.3
UterusCorpus17.65
WholeBlood65.65
Wholebrain148.25
colon16.95
pineal_day105.9
pineal_night120.98
retina41.425
small_intestine16.45
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P226278
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.15 ± 0.51
Basal Forebrain4.13 ± 0.59
Basal Part of Pons4.06 ± 0.39
Cerebellar Cortex3.84 ± 0.37
Cerebellar Nuclei4.06 ± 0.34
Claustrum3.92 ± 0.89
Epithalamus4.12 ± 0.44
Frontal Lobe4.34 ± 0.44
Globus Pallidus4.53 ± 0.36
Hypothalamus4.14 ± 0.46
Insula4.51 ± 0.39
Limbic Lobe4.26 ± 0.7
Mesencephalon4.23 ± 0.54
Myelencephalon4.25 ± 0.51
Occipital Lobe3.86 ± 0.57
Parietal Lobe4.11 ± 0.51
Pontine Tegmentum4.18 ± 0.57
Striatum4.74 ± 0.44
Subthalamus3.98 ± 0.57
Temporal Lobe4.31 ± 0.34
Thalamus4.21 ± 0.6
White Matter5.16 ± 0.12
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Phf15CBCerebellum27.5
31.2
Phf15CTXCerebral cortex96.03
76.77
Phf15HIPHippocampal region40.8
54.54
Phf15HPFHippocampal formation51.22
55.34
Phf15HYHypothalamus29.72
22.31
Phf15LSXLateral septal complex46.85
35.82
Phf15MBMidbrain38.96
33.68
Phf15MYMedulla28.42
28.66
Phf15OLFOlfactory bulb61.89
50.61
Phf15PPons28.36
27.81
Phf15PALPallidum36.1
30.45
Phf15RHPRetrohippocampal region69.33
58.1
Phf15sAMYStriatum-like amygdalar nuclei66
47.27
Phf15STRStriatum63.49
45.33
Phf15STRdStriatum dorsal region70.36
50.81
Phf15STRvStriatum ventral region47.68
32.28
Phf15THThalamus27.24
21.81
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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