AutismKB 2.0

Annotation Detail for KHNYN


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Basic Information Top
Gene Symbol:KHNYN ( KIAA0323 )
Gene Full Name: KH and NYN domain containing
Band: 14q12
Quick LinksEntrez ID:23351; OMIM: NA; Uniprot ID:KHNYN_HUMAN; ENSEMBL ID: ENSG00000100441; HGNC ID: 20166
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body8 / 70761113
blastocyst4 / 6231964
fetus11 / 56401219
neonate0 / 310970 
infant2 / 2362084
juvenile2 / 5555635
adult142 / 193912173
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma2 / 17475114
breast (mammary gland) tumor3 / 9417831
cervical tumor0 / 343660 
chondrosarcoma6 / 8282372
colorectal tumor9 / 11424678
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor11 / 26384541
glioma7 / 10688365
head and neck tumor13 / 13630295
kidney tumor1 / 6895914
leukemia5 / 9584252
liver tumor5 / 9635951
lung tumor1 / 1031279
lymphoma6 / 7175583
non-neoplasia8 / 9725082
normal148 / 336030744
ovarian tumor8 / 76682104
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer21 / 102680204
retinoblastoma4 / 4635686
skin tumor3 / 12494924
soft tissue/muscle tissue tumor6 / 12519147
uterine tumor8 / 9025788
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland1 / 3319730
ascites1 / 4001524
bladder2 / 2975767
blood5 / 12347840
bone3 / 7165541
bone marrow2 / 4880140
brain30 / 110098927
cervix0 / 481710 
connective tissue9 / 14925560
ear2 / 16212123
embryonic tissue14 / 21572264
esophagus0 / 202090 
eye11 / 21105452
heart2 / 8962622
intestine25 / 234472106
kidney7 / 21177733
larynx6 / 24145248
liver6 / 20774328
lung16 / 33697447
lymph4 / 4427090
lymph node9 / 9161098
mammary gland6 / 15327139
mouth6 / 6705289
muscle3 / 10771527
nerve0 / 157680 
ovary7 / 10205168
pancreas6 / 21481227
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta32 / 280825113
prostate25 / 189345132
salivary gland1 / 2015549
skin8 / 21057437
spleen4 / 5395274
stomach3 / 9661931
testis12 / 33044236
thymus8 / 8113198
thyroid2 / 4747342
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus16 / 23287868
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 212356_at
Cell line Expression level Expression bar
721_B_lymphoblasts22.65
Adipocyte5.95
AdrenalCortex6
Adrenalgland4.9
Amygdala6.2
Appendix5.8
AtrioventricularNode4.3
BDCA4+_DentriticCells8.8
Bonemarrow6
BronchialEpithelialCells6.15
CD105+_Endothelial5.9
CD14+_Monocytes6.2
CD19+_BCells(neg._sel.)10.95
CD33+_Myeloid8.55
CD34+7.55
CD4+_Tcells23.4
CD56+_NKCells9.7
CD71+_EarlyErythroid21.2
CD8+_Tcells20.3
CardiacMyocytes7.45
Caudatenucleus5.15
Cerebellum4.75
CerebellumPeduncles10
CiliaryGanglion4
CingulateCortex5.35
Colorectaladenocarcinoma5.85
DorsalRootGanglion4.35
FetalThyroid8.95
Fetalbrain5.85
Fetalliver5.1
Fetallung7.9
GlobusPallidus3.95
Heart7.3
Hypothalamus6.45
Kidney4.6
Leukemia_chronicMyelogenousK-5625.8
Leukemia_promyelocytic-HL-609.4
Leukemialymphoblastic(MOLT-4)5.45
Liver7.6
Lung6.5
Lymphnode34.95
Lymphoma_burkitts(Daudi)8.05
Lymphoma_burkitts(Raji)10.05
MedullaOblongata5.2
OccipitalLobe4.95
OlfactoryBulb6
Ovary4
Pancreas4.7
PancreaticIslet9
ParietalLobe6
Pituitary6.7
Placenta8.7
Pons5.5
PrefrontalCortex7.15
Prostate6.9
Salivarygland4.65
SkeletalMuscle6.5
Skin4.4
SmoothMuscle6.65
Spinalcord6.2
SubthalamicNucleus5.2
SuperiorCervicalGanglion6.45
TemporalLobe5.25
Testis4.9
TestisGermCell4.75
TestisIntersitial4.9
TestisLeydigCell5.7
TestisSeminiferousTubule5
Thalamus5.9
Thymus5.45
Thyroid7.35
Tongue5.6
Tonsil9.75
Trachea5
TrigeminalGanglion5.9
Uterus6.3
UterusCorpus5.2
WholeBlood10.95
Wholebrain5.05
colon6.45
pineal_day6.98
pineal_night6.74
retina7.175
small_intestine7.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P205268
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.03 ± 0.27
Basal Forebrain6.51 ± 0.18
Basal Part of Pons5.68 ± 0.32
Cerebellar Cortex6.71 ± 0.28
Cerebellar Nuclei6.4 ± 0.37
Claustrum6.08 ± 0.45
Epithalamus6.39 ± 0.47
Frontal Lobe6 ± 0.46
Globus Pallidus6.74 ± 0.7
Hypothalamus6.35 ± 0.33
Insula6.07 ± 0.49
Limbic Lobe5.79 ± 0.56
Mesencephalon6.33 ± 0.48
Myelencephalon6.25 ± 0.39
Occipital Lobe6.33 ± 0.51
Parietal Lobe6.2 ± 0.42
Pontine Tegmentum6.18 ± 0.48
Striatum6.11 ± 0.57
Subthalamus6.27 ± 0.11
Temporal Lobe5.99 ± 0.41
Thalamus6.34 ± 0.31
White Matter7.2 ± 0.44
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
9130227C08RikCBCerebellum73.79
99.76
9130227C08RikCTXCerebral cortex45.13
29.33
9130227C08RikHIPHippocampal region29.54
28.14
9130227C08RikHPFHippocampal formation33.03
28.67
9130227C08RikHYHypothalamus6.81
4.62
9130227C08RikLSXLateral septal complex3.57
2.12
9130227C08RikMBMidbrain19.49
17.12
9130227C08RikMYMedulla17.84
15.28
9130227C08RikOLFOlfactory bulb25.42
17.55
9130227C08RikPPons12.86
12.63
9130227C08RikPALPallidum10.44
8.33
9130227C08RikRHPRetrohippocampal region38.31
29.15
9130227C08RiksAMYStriatum-like amygdalar nuclei27.17
20.02
9130227C08RikSTRStriatum18.72
12.6
9130227C08RikSTRdStriatum dorsal region20.75
14.19
9130227C08RikSTRvStriatum ventral region12.08
6.93
9130227C08RikTHThalamus12.25
9.11
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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