AutismKB 2.0

Annotation Detail for VPS8


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Basic Information Top
Gene Symbol:VPS8 ( FLJ32099,KIAA0804 )
Gene Full Name: vacuolar protein sorting 8 homolog (S. cerevisiae)
Band: 3q27.2
Quick LinksEntrez ID:23355; OMIM: NA; Uniprot ID:VPS8_HUMAN; ENSEMBL ID: ENSG00000156931; HGNC ID: 29122
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst5 / 6231980
fetus35 / 56401262
neonate2 / 3109764
infant0 / 236200 
juvenile0 / 555560 
adult91 / 193912146
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma2 / 17475114
breast (mammary gland) tumor2 / 9417821
cervical tumor2 / 3436658
chondrosarcoma5 / 8282360
colorectal tumor5 / 11424643
esophageal tumor1 / 1729057
gastrointestinal tumor0 / 1193690 
germ cell tumor15 / 26384556
glioma7 / 10688365
head and neck tumor3 / 13630222
kidney tumor1 / 6895914
leukemia4 / 9584241
liver tumor6 / 9635962
lung tumor3 / 10312729
lymphoma4 / 7175555
non-neoplasia3 / 9725030
normal136 / 336030740
ovarian tumor0 / 766820 
pancreatic tumor7 / 10461666
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer1 / 1026809
retinoblastoma1 / 4635621
skin tumor3 / 12494924
soft tissue/muscle tissue tumor26 / 125191207
uterine tumor8 / 9025788
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder2 / 2975767
blood4 / 12347832
bone4 / 7165555
bone marrow1 / 4880120
brain59 / 110098953
cervix2 / 4817141
connective tissue25 / 149255167
ear1 / 1621261
embryonic tissue11 / 21572250
esophagus1 / 2020949
eye8 / 21105437
heart3 / 8962633
intestine7 / 23447229
kidney4 / 21177718
larynx0 / 241450 
liver7 / 20774333
lung11 / 33697432
lymph1 / 4427022
lymph node1 / 9161010
mammary gland5 / 15327132
mouth2 / 6705229
muscle9 / 10771583
nerve1 / 1576863
ovary1 / 1020519
pancreas9 / 21481241
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta8 / 28082528
prostate1 / 1893455
salivary gland1 / 2015549
skin4 / 21057418
spleen3 / 5395255
stomach0 / 966190 
testis28 / 33044284
thymus6 / 8113173
thyroid0 / 474730 
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord2 / 13680146
uterus16 / 23287868
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 209553_at
Cell line Expression level Expression bar
721_B_lymphoblasts9
Adipocyte8.55
AdrenalCortex9.05
Adrenalgland7.2
Amygdala11.85
Appendix9.1
AtrioventricularNode6.9
BDCA4+_DentriticCells9.95
Bonemarrow8.35
BronchialEpithelialCells8.4
CD105+_Endothelial8.8
CD14+_Monocytes11.7
CD19+_BCells(neg._sel.)9.15
CD33+_Myeloid12.85
CD34+11.2
CD4+_Tcells9.7
CD56+_NKCells18.6
CD71+_EarlyErythroid8.1
CD8+_Tcells12.85
CardiacMyocytes10.6
Caudatenucleus7.9
Cerebellum7
CerebellumPeduncles9.5
CiliaryGanglion6
CingulateCortex12.15
Colorectaladenocarcinoma9.8
DorsalRootGanglion8.25
FetalThyroid9.6
Fetalbrain17.3
Fetalliver7.9
Fetallung7.4
GlobusPallidus6.25
Heart10.85
Hypothalamus19
Kidney6.95
Leukemia_chronicMyelogenousK-5627.55
Leukemia_promyelocytic-HL-607.65
Leukemialymphoblastic(MOLT-4)6.85
Liver11.2
Lung9.55
Lymphnode9.6
Lymphoma_burkitts(Daudi)11.05
Lymphoma_burkitts(Raji)11.65
MedullaOblongata10.95
OccipitalLobe8
OlfactoryBulb12.2
Ovary5.75
Pancreas6.9
PancreaticIslet9.05
ParietalLobe9.3
Pituitary12.25
Placenta8.75
Pons8.8
PrefrontalCortex24.9
Prostate10.35
Salivarygland6.9
SkeletalMuscle9.7
Skin7.15
SmoothMuscle9.7
Spinalcord15.4
SubthalamicNucleus9.3
SuperiorCervicalGanglion19.65
TemporalLobe7.8
Testis7.55
TestisGermCell8.55
TestisIntersitial7.3
TestisLeydigCell10.85
TestisSeminiferousTubule11.15
Thalamus14.3
Thymus6.8
Thyroid11.05
Tongue8.45
Tonsil8.5
Trachea7.1
TrigeminalGanglion8.35
Uterus7.25
UterusCorpus7.7
WholeBlood20.45
Wholebrain7.3
colon8.7
pineal_day16.84
pineal_night15.48
retina14.55
small_intestine8.45
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P431587
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.14 ± 0.31
Basal Forebrain6.78 ± 0.2
Basal Part of Pons7.01 ± 0.22
Cerebellar Cortex6.83 ± 0.25
Cerebellar Nuclei7.08 ± 0.38
Claustrum7.27 ± 0.45
Epithalamus6.85 ± 0.44
Frontal Lobe6.9 ± 0.3
Globus Pallidus7.19 ± 0.3
Hypothalamus6.81 ± 0.22
Insula6.96 ± 0.26
Limbic Lobe7.15 ± 0.28
Mesencephalon7.01 ± 0.35
Myelencephalon6.93 ± 0.33
Occipital Lobe7.24 ± 0.32
Parietal Lobe7.01 ± 0.27
Pontine Tegmentum6.93 ± 0.26
Striatum6.69 ± 0.35
Subthalamus6.82 ± 0.19
Temporal Lobe6.89 ± 0.27
Thalamus6.93 ± 0.21
White Matter7.53 ± 0.22
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
AI315068CBCerebellum8
9.32
AI315068CTXCerebral cortex100
84.73
AI315068HIPHippocampal region33.61
49.8
AI315068HPFHippocampal formation35.99
42.97
AI315068HYHypothalamus8.56
8.38
AI315068LSXLateral septal complex23.85
17.32
AI315068MBMidbrain8.21
8.53
AI315068MYMedulla9.37
13.07
AI315068OLFOlfactory bulb54.92
47.89
AI315068PPons10.3
13.81
AI315068PALPallidum13.66
14.44
AI315068RHPRetrohippocampal region40.53
33.89
AI315068sAMYStriatum-like amygdalar nuclei15.83
12.1
AI315068STRStriatum14.53
11.61
AI315068STRdStriatum dorsal region13.36
11.25
AI315068STRvStriatum ventral region15.68
11.21
AI315068THThalamus30.48
30.43
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00024191 15 961 975 AMDHIEELVSLKPCK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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