AutismKB 2.0

Annotation Detail for ANGEL1


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Basic Information Top
Gene Symbol:ANGEL1 ( FLJ60172,KIAA0759 )
Gene Full Name: angel homolog 1 (Drosophila)
Band: 14q24.3
Quick LinksEntrez ID:23357; OMIM: NA; Uniprot ID:ANGE1_HUMAN; ENSEMBL ID: ENSG00000013523; HGNC ID: 19961
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst5 / 6231980
fetus17 / 56401230
neonate0 / 310970 
infant0 / 236200 
juvenile3 / 5555653
adult38 / 193912119
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma2 / 17475114
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor6 / 26384522
glioma5 / 10688346
head and neck tumor1 / 1363027
kidney tumor2 / 6895929
leukemia1 / 9584210
liver tumor6 / 9635962
lung tumor2 / 10312719
lymphoma2 / 7175527
non-neoplasia5 / 9725051
normal84 / 336030724
ovarian tumor1 / 7668213
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer4 / 10268038
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder3 / 29757100
blood1 / 1234788
bone1 / 7165513
bone marrow1 / 4880120
brain29 / 110098926
cervix0 / 481710 
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue8 / 21572237
esophagus0 / 202090 
eye9 / 21105442
heart0 / 896260 
intestine5 / 23447221
kidney7 / 21177733
larynx0 / 241450 
liver6 / 20774328
lung8 / 33697423
lymph2 / 4427045
lymph node1 / 9161010
mammary gland3 / 15327119
mouth1 / 6705214
muscle1 / 1077159
nerve0 / 157680 
ovary1 / 1020519
pancreas2 / 2148129
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta4 / 28082514
prostate4 / 18934521
salivary gland0 / 201550 
skin1 / 2105744
spleen4 / 5395274
stomach1 / 9661910
testis32 / 33044296
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus4 / 23287817
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 36865_at
Cell line Expression level Expression bar
721_B_lymphoblasts23.95
Adipocyte15.7
AdrenalCortex26.95
Adrenalgland15.5
Amygdala20.05
Appendix18.35
AtrioventricularNode20.6
BDCA4+_DentriticCells15.5
Bonemarrow18.05
BronchialEpithelialCells15.85
CD105+_Endothelial19.9
CD14+_Monocytes18.75
CD19+_BCells(neg._sel.)22.15
CD33+_Myeloid27.9
CD34+36.3
CD4+_Tcells19.25
CD56+_NKCells23.75
CD71+_EarlyErythroid16.9
CD8+_Tcells17.6
CardiacMyocytes21.65
Caudatenucleus15.95
Cerebellum14.7
CerebellumPeduncles20.95
CiliaryGanglion13.45
CingulateCortex18.8
Colorectaladenocarcinoma28.6
DorsalRootGanglion16.05
FetalThyroid19.15
Fetalbrain18.6
Fetalliver16.15
Fetallung14.35
GlobusPallidus14.4
Heart28.8
Hypothalamus21.1
Kidney15.7
Leukemia_chronicMyelogenousK-56216.6
Leukemia_promyelocytic-HL-6017.05
Leukemialymphoblastic(MOLT-4)15.85
Liver28.8
Lung19.9
Lymphnode15.05
Lymphoma_burkitts(Daudi)23.95
Lymphoma_burkitts(Raji)28.2
MedullaOblongata13.05
OccipitalLobe15.95
OlfactoryBulb18.4
Ovary12.8
Pancreas16.8
PancreaticIslet19.5
ParietalLobe21.45
Pituitary21.6
Placenta17.9
Pons16.95
PrefrontalCortex22.75
Prostate20.8
Salivarygland14.5
SkeletalMuscle22.2
Skin15.6
SmoothMuscle19.8
Spinalcord19.15
SubthalamicNucleus18.3
SuperiorCervicalGanglion19.9
TemporalLobe16.25
Testis25.95
TestisGermCell24.5
TestisIntersitial24.55
TestisLeydigCell28.1
TestisSeminiferousTubule16.65
Thalamus18.2
Thymus10.45
Thyroid21.05
Tongue19.1
Tonsil19
Trachea13.6
TrigeminalGanglion20
Uterus12.85
UterusCorpus16.15
WholeBlood10.85
Wholebrain15
colon15.95
pineal_day23.68
pineal_night25.46
retina21.625
small_intestine16.7
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_11605_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.8 ± 0.19
Basal Forebrain4.97 ± 0.25
Basal Part of Pons4.46 ± 0.53
Cerebellar Cortex4.54 ± 0.31
Cerebellar Nuclei4.89 ± 0.68
Claustrum4.73 ± 0.54
Epithalamus4.79 ± 0.4
Frontal Lobe4.61 ± 0.38
Globus Pallidus5.49 ± 0.26
Hypothalamus4.51 ± 0.57
Insula4.45 ± 0.28
Limbic Lobe4.76 ± 0.47
Mesencephalon4.83 ± 0.52
Myelencephalon4.73 ± 0.47
Occipital Lobe4.84 ± 0.39
Parietal Lobe4.73 ± 0.43
Pontine Tegmentum4.77 ± 0.46
Striatum5.27 ± 0.41
Subthalamus4.52 ± 0.19
Temporal Lobe4.65 ± 0.42
Thalamus4.57 ± 0.48
White Matter6.3 ± 0.08
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Angel1CBCerebellum0.55
0.94
Angel1CTXCerebral cortex5.16
3.48
Angel1HIPHippocampal region0.83
0.66
Angel1HPFHippocampal formation0.55
0.45
Angel1HYHypothalamus0.04
0.04
Angel1LSXLateral septal complex0.05
0.05
Angel1MBMidbrain0.11
0.13
Angel1MYMedulla0.63
0.99
Angel1OLFOlfactory bulb1.99
1.47
Angel1PPons0.61
1
Angel1PALPallidum0.64
0.64
Angel1RHPRetrohippocampal region0.09
0.18
Angel1sAMYStriatum-like amygdalar nuclei0.23
0.26
Angel1STRStriatum0.2
0.15
Angel1STRdStriatum dorsal region0.1
0.06
Angel1STRvStriatum ventral region0.56
0.36
Angel1THThalamus0.35
0.27
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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