AutismKB 2.0

Annotation Detail for FNBP4


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Basic Information Top
Gene Symbol:FNBP4 ( DKFZp686M14102,DKFZp779I1064,FBP30,FLJ41904,KIAA1014 )
Gene Full Name: formin binding protein 4
Band: 11p11.2
Quick LinksEntrez ID:23360; OMIM: NA; Uniprot ID:FNBP4_HUMAN; ENSEMBL ID: ENSG00000109920; HGNC ID: 19752
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body8 / 70761113
blastocyst5 / 6231980
fetus56 / 56401299
neonate0 / 310970 
infant1 / 2362042
juvenile1 / 5555617
adult157 / 193912180
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma1 / 1747557
breast (mammary gland) tumor4 / 9417842
cervical tumor5 / 34366145
chondrosarcoma10 / 82823120
colorectal tumor19 / 114246166
esophageal tumor2 / 17290115
gastrointestinal tumor10 / 11936983
germ cell tumor17 / 26384564
glioma7 / 10688365
head and neck tumor9 / 13630266
kidney tumor2 / 6895929
leukemia12 / 95842125
liver tumor3 / 9635931
lung tumor6 / 10312758
lymphoma2 / 7175527
non-neoplasia8 / 9725082
normal230 / 336030768
ovarian tumor8 / 76682104
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer4 / 10268038
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor13 / 90257144
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland4 / 33197120
ascites6 / 40015149
bladder0 / 297570 
blood11 / 12347889
bone4 / 7165555
bone marrow1 / 4880120
brain67 / 110098960
cervix6 / 48171124
connective tissue12 / 14925580
ear4 / 16212246
embryonic tissue21 / 21572297
esophagus2 / 2020998
eye9 / 21105442
heart9 / 89626100
intestine28 / 234472119
kidney7 / 21177733
larynx0 / 241450 
liver16 / 20774377
lung22 / 33697465
lymph0 / 442700 
lymph node16 / 91610174
mammary gland7 / 15327145
mouth3 / 6705244
muscle7 / 10771564
nerve2 / 15768126
ovary8 / 10205178
pancreas5 / 21481223
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland2 / 16585120
placenta13 / 28082546
prostate10 / 18934552
salivary gland0 / 201550 
skin7 / 21057433
spleen5 / 5395292
stomach3 / 9661931
testis24 / 33044272
thymus6 / 8113173
thyroid5 / 47473105
tonsil0 / 169990 
trachea6 / 52413114
umbilical cord0 / 136800 
uterus26 / 232878111
vascular4 / 5178077
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 212232_at
Cell line Expression level Expression bar
721_B_lymphoblasts125.35
Adipocyte24.7
AdrenalCortex52.8
Adrenalgland25.3
Amygdala30.3
Appendix50.15
AtrioventricularNode17.1
BDCA4+_DentriticCells274.05
Bonemarrow21.15
BronchialEpithelialCells17.8
CD105+_Endothelial66.6
CD14+_Monocytes58.2
CD19+_BCells(neg._sel.)465.4
CD33+_Myeloid176.2
CD34+239.05
CD4+_Tcells394
CD56+_NKCells268.4
CD71+_EarlyErythroid42.25
CD8+_Tcells614.15
CardiacMyocytes14.3
Caudatenucleus28.85
Cerebellum22.85
CerebellumPeduncles34.15
CiliaryGanglion18.85
CingulateCortex26.05
Colorectaladenocarcinoma32.15
DorsalRootGanglion25.05
FetalThyroid84.3
Fetalbrain51.5
Fetalliver26.85
Fetallung104.2
GlobusPallidus22.6
Heart12
Hypothalamus75.85
Kidney24.6
Leukemia_chronicMyelogenousK-56257.7
Leukemia_promyelocytic-HL-60116.45
Leukemialymphoblastic(MOLT-4)270.85
Liver20.8
Lung15.2
Lymphnode180
Lymphoma_burkitts(Daudi)134.25
Lymphoma_burkitts(Raji)94.1
MedullaOblongata28.65
OccipitalLobe28.7
OlfactoryBulb33.85
Ovary32.45
Pancreas43.7
PancreaticIslet30.2
ParietalLobe26.4
Pituitary40.45
Placenta28.7
Pons22.9
PrefrontalCortex63.05
Prostate31.55
Salivarygland91.05
SkeletalMuscle29.85
Skin24.5
SmoothMuscle19.75
Spinalcord34.15
SubthalamicNucleus27
SuperiorCervicalGanglion19.05
TemporalLobe26.7
Testis14.4
TestisGermCell47.35
TestisIntersitial20
TestisLeydigCell24.95
TestisSeminiferousTubule26.05
Thalamus31.05
Thymus29.45
Thyroid40.55
Tongue35.25
Tonsil92.45
Trachea26.05
TrigeminalGanglion32.1
Uterus45.35
UterusCorpus29.8
WholeBlood34.75
Wholebrain19.25
colon30.6
pineal_day68.78
pineal_night76.58
retina35.1
small_intestine28.05
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_7594_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.15 ± 0.42
Basal Forebrain7.99 ± 0.28
Basal Part of Pons7.44 ± 0.32
Cerebellar Cortex7.77 ± 0.34
Cerebellar Nuclei7.68 ± 0.44
Claustrum8.26 ± 0.61
Epithalamus7.3 ± 0.18
Frontal Lobe7.4 ± 0.43
Globus Pallidus8.34 ± 0.19
Hypothalamus7.37 ± 0.18
Insula7.48 ± 0.48
Limbic Lobe7.86 ± 0.58
Mesencephalon7.76 ± 0.46
Myelencephalon7.69 ± 0.56
Occipital Lobe8.18 ± 0.57
Parietal Lobe7.74 ± 0.49
Pontine Tegmentum7.67 ± 0.46
Striatum8.01 ± 0.51
Subthalamus7.48 ± 0.13
Temporal Lobe7.57 ± 0.48
Thalamus7.63 ± 0.3
White Matter8.81 ± 0.48
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Fnbp4sAMYStriatum-like amygdalar nuclei100
83.07
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00009823 22 653 674 DKTGTDSNSTESSETSTGSLCK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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