AutismKB 2.0

Annotation Detail for PSD3


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Basic Information Top
Gene Symbol:PSD3 ( DKFZp761K1423,EFA6R,HCA67 )
Gene Full Name: pleckstrin and Sec7 domain containing 3
Band: 8p22
Quick LinksEntrez ID:23362; OMIM: NA; Uniprot ID:PSD3_HUMAN; ENSEMBL ID: ENSG00000156011; HGNC ID: 19093
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst1 / 6231916
fetus80 / 564012141
neonate0 / 310970 
infant3 / 23620127
juvenile4 / 5555671
adult129 / 193912166
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor5 / 9417853
cervical tumor0 / 343660 
chondrosarcoma11 / 82823132
colorectal tumor4 / 11424635
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor11 / 26384541
glioma6 / 10688356
head and neck tumor10 / 13630273
kidney tumor6 / 6895987
leukemia4 / 9584241
liver tumor3 / 9635931
lung tumor5 / 10312748
lymphoma1 / 7175513
non-neoplasia5 / 9725051
normal389 / 3360307115
ovarian tumor2 / 7668226
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer2 / 10268019
retinoblastoma1 / 4635621
skin tumor4 / 12494932
soft tissue/muscle tissue tumor14 / 125191111
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland5 / 33197150
ascites2 / 4001549
bladder2 / 2975767
blood0 / 1234780 
bone5 / 7165569
bone marrow2 / 4880140
brain218 / 1100989198
cervix0 / 481710 
connective tissue20 / 149255133
ear1 / 1621261
embryonic tissue12 / 21572255
esophagus1 / 2020949
eye12 / 21105456
heart4 / 8962644
intestine8 / 23447234
kidney10 / 21177747
larynx0 / 241450 
liver9 / 20774343
lung15 / 33697444
lymph0 / 442700 
lymph node5 / 9161054
mammary gland11 / 15327171
mouth8 / 67052119
muscle11 / 107715102
nerve3 / 15768190
ovary2 / 10205119
pancreas3 / 21481213
parathyroid8 / 20539389
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta2 / 2808257
prostate4 / 18934521
salivary gland0 / 201550 
skin12 / 21057456
spleen0 / 539520 
stomach1 / 9661910
testis45 / 330442136
thymus1 / 8113112
thyroid2 / 4747342
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus10 / 23287842
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218613_at
Cell line Expression level Expression bar
721_B_lymphoblasts10.25
Adipocyte8.4
AdrenalCortex13.8
Adrenalgland66.9
Amygdala1797.8
Appendix10.25
AtrioventricularNode8.15
BDCA4+_DentriticCells9.05
Bonemarrow9.2
BronchialEpithelialCells8.45
CD105+_Endothelial8.95
CD14+_Monocytes9.45
CD19+_BCells(neg._sel.)8.95
CD33+_Myeloid10.6
CD34+10.65
CD4+_Tcells8.9
CD56+_NKCells9.8
CD71+_EarlyErythroid8.3
CD8+_Tcells8.05
CardiacMyocytes13.75
Caudatenucleus441.3
Cerebellum472.55
CerebellumPeduncles1193.85
CiliaryGanglion7.35
CingulateCortex583.85
Colorectaladenocarcinoma8.85
DorsalRootGanglion7.6
FetalThyroid9.55
Fetalbrain909.15
Fetalliver8.4
Fetallung11.4
GlobusPallidus197.25
Heart12.95
Hypothalamus374.15
Kidney7.45
Leukemia_chronicMyelogenousK-5627.6
Leukemia_promyelocytic-HL-607.7
Leukemialymphoblastic(MOLT-4)6.5
Liver12.85
Lung9.55
Lymphnode7.65
Lymphoma_burkitts(Daudi)11.85
Lymphoma_burkitts(Raji)12.7
MedullaOblongata454.4
OccipitalLobe860
OlfactoryBulb6.85
Ovary16.3
Pancreas7.2
PancreaticIslet9.65
ParietalLobe445.05
Pituitary29.25
Placenta8.5
Pons305.55
PrefrontalCortex1623.45
Prostate10.55
Salivarygland7.45
SkeletalMuscle12.1
Skin10.15
SmoothMuscle83.8
Spinalcord20.95
SubthalamicNucleus574.7
SuperiorCervicalGanglion11
TemporalLobe301.05
Testis7.5
TestisGermCell6.95
TestisIntersitial7.5
TestisLeydigCell8.75
TestisSeminiferousTubule7.35
Thalamus439.15
Thymus6.5
Thyroid15.6
Tongue9.45
Tonsil8.35
Trachea15
TrigeminalGanglion11.75
Uterus44.5
UterusCorpus8.7
WholeBlood9.2
Wholebrain447.3
colon9.3
pineal_day182.14
pineal_night217.46
retina35.8
small_intestine15.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P216167
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala12.53 ± 0.45
Basal Forebrain11.68 ± 0.21
Basal Part of Pons11.63 ± 0.21
Cerebellar Cortex12.4 ± 0.21
Cerebellar Nuclei11.69 ± 0.52
Claustrum11.5 ± 0.34
Epithalamus11.48 ± 0.28
Frontal Lobe12.09 ± 0.43
Globus Pallidus10.3 ± 0.38
Hypothalamus11.36 ± 0.66
Insula12.45 ± 0.29
Limbic Lobe12.51 ± 0.43
Mesencephalon11.96 ± 0.64
Myelencephalon11.93 ± 0.38
Occipital Lobe11.6 ± 0.57
Parietal Lobe11.98 ± 0.43
Pontine Tegmentum12 ± 0.43
Striatum12.2 ± 0.37
Subthalamus11.12 ± 0.29
Temporal Lobe12.33 ± 0.42
Thalamus12.04 ± 0.41
White Matter11.06 ± 0.43
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Psd3CBCerebellum0.55
0.99
Psd3CTXCerebral cortex0.55
0.47
Psd3HIPHippocampal region0.59
0.56
Psd3HPFHippocampal formation0.53
0.49
Psd3HYHypothalamus0.05
0.13
Psd3LSXLateral septal complex0
0
Psd3MBMidbrain0.22
0.4
Psd3MYMedulla0.34
0.39
Psd3OLFOlfactory bulb0.47
0.42
Psd3PPons0.29
0.61
Psd3PALPallidum0.14
0.15
Psd3RHPRetrohippocampal region0.44
0.4
Psd3sAMYStriatum-like amygdalar nuclei0.36
0.27
Psd3STRStriatum0.1
0.15
Psd3STRdStriatum dorsal region0.09
0.14
Psd3STRvStriatum ventral region0.01
0
Psd3THThalamus0.3
0.36
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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