AutismKB 2.0

Annotation Detail for LARP1


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Basic Information Top
Gene Symbol:LARP1 ( KIAA0731,LARP,MGC19556 )
Gene Full Name: La ribonucleoprotein domain family, member 1
Band: 5q33.2
Quick LinksEntrez ID:23367; OMIM: 612059; Uniprot ID:LARP1_HUMAN; ENSEMBL ID: ENSG00000155506; HGNC ID: 29531
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body18 / 70761254
blastocyst13 / 62319208
fetus61 / 564012108
neonate0 / 310970 
infant0 / 236200 
juvenile8 / 55556143
adult295 / 1939121152
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor56 / 94178594
cervical tumor8 / 34366232
chondrosarcoma17 / 82823205
colorectal tumor26 / 114246227
esophageal tumor0 / 172900 
gastrointestinal tumor21 / 119369175
germ cell tumor43 / 263845162
glioma24 / 106883224
head and neck tumor17 / 136302124
kidney tumor10 / 68959145
leukemia17 / 95842177
liver tumor13 / 96359134
lung tumor18 / 103127174
lymphoma18 / 71755250
non-neoplasia10 / 97250102
normal384 / 3360307114
ovarian tumor10 / 76682130
pancreatic tumor19 / 104616181
primitive neuroectodermal tumor of the CNS15 / 125680119
prostate cancer10 / 10268097
retinoblastoma5 / 46356107
skin tumor28 / 124949224
soft tissue/muscle tissue tumor16 / 125191127
uterine tumor11 / 90257121
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites8 / 40015199
bladder1 / 2975733
blood13 / 123478105
bone9 / 71655125
bone marrow2 / 4880140
brain105 / 110098995
cervix8 / 48171166
connective tissue18 / 149255120
ear2 / 16212123
embryonic tissue45 / 215722208
esophagus0 / 202090 
eye35 / 211054165
heart12 / 89626133
intestine40 / 234472170
kidney18 / 21177784
larynx2 / 2414582
liver23 / 207743110
lung54 / 336974160
lymph13 / 44270293
lymph node42 / 91610458
mammary gland63 / 153271411
mouth3 / 6705244
muscle14 / 107715129
nerve2 / 15768126
ovary15 / 102051146
pancreas26 / 214812121
parathyroid3 / 20539146
pharynx2 / 4132848
pituitary gland3 / 16585180
placenta23 / 28082581
prostate16 / 18934584
salivary gland3 / 20155148
skin50 / 210574237
spleen2 / 5395237
stomach8 / 9661982
testis31 / 33044293
thymus4 / 8113149
thyroid11 / 47473231
tonsil1 / 1699958
trachea0 / 524130 
umbilical cord0 / 136800 
uterus27 / 232878115
vascular4 / 5178077
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 210966_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts162.25
Adipocyte43.4
AdrenalCortex38.35
Adrenalgland22.9
Amygdala13.1
Appendix13.75
AtrioventricularNode11.05
BDCA4+_DentriticCells27.4
Bonemarrow32
BronchialEpithelialCells45.45
CD105+_Endothelial40.65
CD14+_Monocytes18.6
CD19+_BCells(neg._sel.)34.15
CD33+_Myeloid37.55
CD34+54.7
CD4+_Tcells38.85
CD56+_NKCells21.8
CD71+_EarlyErythroid154.35
CD8+_Tcells35.15
CardiacMyocytes30.35
Caudatenucleus12.2
Cerebellum13.95
CerebellumPeduncles37.35
CiliaryGanglion12.7
CingulateCortex78.8
Colorectaladenocarcinoma26.25
DorsalRootGanglion14.3
FetalThyroid56.25
Fetalbrain13.65
Fetalliver14.8
Fetallung11.5
GlobusPallidus13.45
Heart22.25
Hypothalamus17.85
Kidney13.7
Leukemia_chronicMyelogenousK-56222.15
Leukemia_promyelocytic-HL-6012.9
Leukemialymphoblastic(MOLT-4)11.5
Liver19.95
Lung24.55
Lymphnode11.8
Lymphoma_burkitts(Daudi)19.55
Lymphoma_burkitts(Raji)18.1
MedullaOblongata32.95
OccipitalLobe39.35
OlfactoryBulb33.65
Ovary11.75
Pancreas13.05
PancreaticIslet37.65
ParietalLobe43.75
Pituitary18.3
Placenta34.4
Pons23.3
PrefrontalCortex42.45
Prostate21.35
Salivarygland8.85
SkeletalMuscle17.85
Skin11
SmoothMuscle54.65
Spinalcord14.7
SubthalamicNucleus24.45
SuperiorCervicalGanglion15.95
TemporalLobe23.4
Testis19.35
TestisGermCell32.95
TestisIntersitial14.4
TestisLeydigCell17.45
TestisSeminiferousTubule28.45
Thalamus14
Thymus15.65
Thyroid17
Tongue21.2
Tonsil38.85
Trachea13.45
TrigeminalGanglion14.2
Uterus12.4
UterusCorpus18.6
WholeBlood12.15
Wholebrain18.9
colon16.1
pineal_day31.48
pineal_night24.42
retina45.575
small_intestine15.55
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P7211
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.57 ± 0.44
Basal Forebrain7.71 ± 0.14
Basal Part of Pons7.73 ± 0.26
Cerebellar Cortex7.44 ± 0.31
Cerebellar Nuclei7.5 ± 0.42
Claustrum7.67 ± 0.38
Epithalamus7.74 ± 0.35
Frontal Lobe7.77 ± 0.36
Globus Pallidus7.31 ± 0.48
Hypothalamus7.72 ± 0.33
Insula7.84 ± 0.33
Limbic Lobe7.87 ± 0.35
Mesencephalon7.62 ± 0.38
Myelencephalon7.65 ± 0.38
Occipital Lobe7.49 ± 0.36
Parietal Lobe7.71 ± 0.35
Pontine Tegmentum7.71 ± 0.43
Striatum7.41 ± 0.43
Subthalamus7.96 ± 0.45
Temporal Lobe7.81 ± 0.31
Thalamus7.76 ± 0.35
White Matter7.3 ± 0.29
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Larp1CBCerebellum26.58
36.2
Larp1CTXCerebral cortex49.05
37.7
Larp1HIPHippocampal region45.98
55.16
Larp1HPFHippocampal formation53.08
54.58
Larp1HYHypothalamus10.56
9.31
Larp1LSXLateral septal complex13.76
11.49
Larp1MBMidbrain9.18
9.34
Larp1MYMedulla17.6
23.15
Larp1OLFOlfactory bulb51.78
44.09
Larp1PPons17.88
21.37
Larp1PALPallidum16.26
16.79
Larp1RHPRetrohippocampal region68.42
56.34
Larp1sAMYStriatum-like amygdalar nuclei32.87
25.77
Larp1STRStriatum23
17.08
Larp1STRdStriatum dorsal region21.44
15.52
Larp1STRvStriatum ventral region22.99
17.34
Larp1THThalamus20.42
18.45
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
LARP1_HUMAN_2 25 2 26 ATQVEPLLPGGATLLQAEEHGGLVR PRIDE
LARP1_HUMAN_446 19 446 464 VQALTTDISLIFAALKDSK PRIDE
LARP1_HUMAN_509 15 509 523 QHYQKETESAPGSPR PRIDE
LARP1_HUMAN_566 13 566 578 PSPARPKKSEESR PRIDE
PAp00001284 26 977 1002 CPSQSSSRPAAMISQPPTPPTGQPVR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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