AutismKB 2.0

Annotation Detail for PPP1R13B


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Basic Information Top
Gene Symbol:PPP1R13B ( ASPP1,KIAA0771,p53BP2-like,p85 )
Gene Full Name: protein phosphatase 1, regulatory (inhibitor) subunit 13B
Band: 14q32.33
Quick LinksEntrez ID:23368; OMIM: 606455; Uniprot ID:ASPP1_HUMAN; ENSEMBL ID: ENSG00000088808; HGNC ID: 14950
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus22 / 56401239
neonate0 / 310970 
infant1 / 2362042
juvenile0 / 555560 
adult76 / 193912139
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor4 / 11424635
esophageal tumor0 / 172900 
gastrointestinal tumor8 / 11936967
germ cell tumor5 / 26384518
glioma0 / 1068830 
head and neck tumor11 / 13630280
kidney tumor3 / 6895943
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor4 / 10312738
lymphoma0 / 717550 
non-neoplasia5 / 9725051
normal123 / 336030736
ovarian tumor3 / 7668239
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer3 / 10268029
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites3 / 4001574
bladder1 / 2975733
blood0 / 1234780 
bone2 / 7165527
bone marrow0 / 488010 
brain43 / 110098939
cervix1 / 4817120
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye15 / 21105471
heart1 / 8962611
intestine20 / 23447285
kidney7 / 21177733
larynx2 / 2414582
liver1 / 2077434
lung10 / 33697429
lymph0 / 442700 
lymph node1 / 9161010
mammary gland4 / 15327126
mouth3 / 6705244
muscle2 / 10771518
nerve0 / 157680 
ovary4 / 10205139
pancreas3 / 21481213
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta2 / 2808257
prostate10 / 18934552
salivary gland0 / 201550 
skin1 / 2105744
spleen2 / 5395237
stomach7 / 9661972
testis38 / 330442114
thymus1 / 8113112
thyroid7 / 47473147
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus6 / 23287825
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 216347_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts24.7
Adipocyte21.05
AdrenalCortex25.1
Adrenalgland19.45
Amygdala27.3
Appendix23.5
AtrioventricularNode17.25
BDCA4+_DentriticCells18.15
Bonemarrow21.7
BronchialEpithelialCells17.5
CD105+_Endothelial22
CD14+_Monocytes21.5
CD19+_BCells(neg._sel.)19.8
CD33+_Myeloid27.35
CD34+26.4
CD4+_Tcells37.25
CD56+_NKCells26.5
CD71+_EarlyErythroid21.95
CD8+_Tcells26.85
CardiacMyocytes27.55
Caudatenucleus30.05
Cerebellum34.6
CerebellumPeduncles53.15
CiliaryGanglion17.25
CingulateCortex37.1
Colorectaladenocarcinoma22.4
DorsalRootGanglion16.85
FetalThyroid36.75
Fetalbrain26.35
Fetalliver18.45
Fetallung19.15
GlobusPallidus25.45
Heart34.8
Hypothalamus27
Kidney22.6
Leukemia_chronicMyelogenousK-56219.45
Leukemia_promyelocytic-HL-6019.1
Leukemialymphoblastic(MOLT-4)15.1
Liver30.2
Lung86.1
Lymphnode18.55
Lymphoma_burkitts(Daudi)28.6
Lymphoma_burkitts(Raji)30.8
MedullaOblongata27.1
OccipitalLobe27.65
OlfactoryBulb17.3
Ovary14.95
Pancreas17.7
PancreaticIslet24.6
ParietalLobe30.85
Pituitary25.6
Placenta22.2
Pons33.1
PrefrontalCortex55.5
Prostate58.15
Salivarygland18.25
SkeletalMuscle32.05
Skin18.05
SmoothMuscle21.75
Spinalcord24.25
SubthalamicNucleus33.45
SuperiorCervicalGanglion26.35
TemporalLobe38.6
Testis47.1
TestisGermCell40.15
TestisIntersitial19.6
TestisLeydigCell22.7
TestisSeminiferousTubule32.05
Thalamus31.1
Thymus16.25
Thyroid263.9
Tongue23.1
Tonsil22.1
Trachea18.25
TrigeminalGanglion23.85
Uterus17.7
UterusCorpus20.6
WholeBlood12.85
Wholebrain47.55
colon23.35
pineal_day62.84
pineal_night43.04
retina49.725
small_intestine22
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_5395_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.09 ± 0.59
Basal Forebrain5.05 ± 0.37
Basal Part of Pons5.51 ± 0.27
Cerebellar Cortex5.43 ± 0.32
Cerebellar Nuclei4.97 ± 0.49
Claustrum5.2 ± 0.6
Epithalamus4.89 ± 0.49
Frontal Lobe5.23 ± 0.48
Globus Pallidus4.21 ± 0.34
Hypothalamus4.77 ± 0.4
Insula5.34 ± 0.45
Limbic Lobe5.43 ± 0.54
Mesencephalon4.96 ± 0.43
Myelencephalon5.06 ± 0.49
Occipital Lobe5.13 ± 0.44
Parietal Lobe5.2 ± 0.49
Pontine Tegmentum5.16 ± 0.55
Striatum5.03 ± 0.4
Subthalamus5.04 ± 0.41
Temporal Lobe5.25 ± 0.41
Thalamus4.98 ± 0.44
White Matter3.57 ± 0.65
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ppp1r13bCBCerebellum80.9
100
Ppp1r13bCTXCerebral cortex100
100
Ppp1r13bHIPHippocampal region100
100
Ppp1r13bHPFHippocampal formation100
100
Ppp1r13bHYHypothalamus72.13
64.85
Ppp1r13bLSXLateral septal complex100
100
Ppp1r13bMBMidbrain74.74
75.18
Ppp1r13bMYMedulla82.05
100
Ppp1r13bOLFOlfactory bulb100
100
Ppp1r13bPPons60.95
73.76
Ppp1r13bPALPallidum61.49
58.06
Ppp1r13bRHPRetrohippocampal region100
100
Ppp1r13bsAMYStriatum-like amygdalar nuclei100
93.86
Ppp1r13bSTRStriatum99.4
80.71
Ppp1r13bSTRdStriatum dorsal region100
80.52
Ppp1r13bSTRvStriatum ventral region84.16
66.56
Ppp1r13bTHThalamus100
100
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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