AutismKB 2.0

Annotation Detail for TENC1


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Basic Information Top
Gene Symbol:TENC1 ( C1-TEN,C1TEN,DKFZp686D13244,FLJ16320,KIAA1075,TNS2 )
Gene Full Name: tensin like C1 domain containing phosphatase (tensin 2)
Band: 12q13.13
Quick LinksEntrez ID:23371; OMIM: 607717; Uniprot ID:TENC1_HUMAN; ENSEMBL ID: ENSG00000111077; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst0 / 623190 
fetus55 / 56401297
neonate0 / 310970 
infant0 / 236200 
juvenile3 / 5555653
adult102 / 193912152
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor0 / 343660 
chondrosarcoma9 / 82823108
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor13 / 26384549
glioma11 / 106883102
head and neck tumor7 / 13630251
kidney tumor5 / 6895972
leukemia0 / 958420 
liver tumor3 / 9635931
lung tumor8 / 10312777
lymphoma1 / 7175513
non-neoplasia4 / 9725041
normal177 / 336030752
ovarian tumor3 / 7668239
pancreatic tumor8 / 10461676
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor8 / 12494964
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor8 / 9025788
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites1 / 4001524
bladder0 / 297570 
blood0 / 1234780 
bone9 / 71655125
bone marrow0 / 488010 
brain45 / 110098940
cervix0 / 481710 
connective tissue8 / 14925553
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye17 / 21105480
heart1 / 8962611
intestine12 / 23447251
kidney23 / 211777108
larynx0 / 241450 
liver4 / 20774319
lung26 / 33697477
lymph0 / 442700 
lymph node1 / 9161010
mammary gland12 / 15327178
mouth0 / 670520 
muscle3 / 10771527
nerve5 / 15768317
ovary3 / 10205129
pancreas19 / 21481288
parathyroid1 / 2053948
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta11 / 28082539
prostate7 / 18934536
salivary gland1 / 2015549
skin11 / 21057452
spleen6 / 53952111
stomach3 / 9661931
testis1 / 3304423
thymus1 / 8113112
thyroid9 / 47473189
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus9 / 23287838
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 212494_at
Cell line Expression level Expression bar
721_B_lymphoblasts12.3
Adipocyte117.2
AdrenalCortex70.35
Adrenalgland94.25
Amygdala33.9
Appendix50.45
AtrioventricularNode40.85
BDCA4+_DentriticCells7.65
Bonemarrow16.1
BronchialEpithelialCells15.95
CD105+_Endothelial9.95
CD14+_Monocytes9.2
CD19+_BCells(neg._sel.)11.2
CD33+_Myeloid9.65
CD34+6.55
CD4+_Tcells11.95
CD56+_NKCells6.55
CD71+_EarlyErythroid13.05
CD8+_Tcells11.5
CardiacMyocytes31.95
Caudatenucleus44
Cerebellum28.45
CerebellumPeduncles43
CiliaryGanglion25.2
CingulateCortex37.55
Colorectaladenocarcinoma24.7
DorsalRootGanglion41.35
FetalThyroid44.45
Fetalbrain30.35
Fetalliver13.45
Fetallung36.5
GlobusPallidus23.8
Heart107.95
Hypothalamus53.75
Kidney43.75
Leukemia_chronicMyelogenousK-56212.85
Leukemia_promyelocytic-HL-6014.35
Leukemialymphoblastic(MOLT-4)16.65
Liver51.75
Lung248.25
Lymphnode26.05
Lymphoma_burkitts(Daudi)29.1
Lymphoma_burkitts(Raji)18.1
MedullaOblongata41.85
OccipitalLobe37.25
OlfactoryBulb56.85
Ovary56.4
Pancreas24.35
PancreaticIslet27.75
ParietalLobe50.85
Pituitary38.25
Placenta37.2
Pons28.7
PrefrontalCortex82.4
Prostate39.35
Salivarygland26.05
SkeletalMuscle42.35
Skin26.4
SmoothMuscle21.65
Spinalcord45
SubthalamicNucleus24.95
SuperiorCervicalGanglion27.3
TemporalLobe24.65
Testis24
TestisGermCell23.25
TestisIntersitial19.6
TestisLeydigCell37.15
TestisSeminiferousTubule31.95
Thalamus26.2
Thymus21.65
Thyroid102.5
Tongue33.1
Tonsil29.45
Trachea34.45
TrigeminalGanglion41.9
Uterus153.3
UterusCorpus38.75
WholeBlood14.45
Wholebrain18.65
colon30.25
pineal_day40.4
pineal_night33.04
retina135.25
small_intestine23.5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_14072_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.89 ± 1.16
Basal Forebrain3.93 ± 0.57
Basal Part of Pons3.18 ± 1.02
Cerebellar Cortex2.9 ± 0.76
Cerebellar Nuclei3.17 ± 1.1
Claustrum4.29 ± 1.02
Epithalamus2.82 ± 1.13
Frontal Lobe3.04 ± 0.97
Globus Pallidus4.96 ± 0.5
Hypothalamus3.03 ± 0.69
Insula3.07 ± 0.86
Limbic Lobe3.7 ± 1.08
Mesencephalon3.82 ± 0.91
Myelencephalon3.49 ± 1.05
Occipital Lobe3.7 ± 1.01
Parietal Lobe3.35 ± 1.09
Pontine Tegmentum3.26 ± 0.96
Striatum4.1 ± 0.89
Subthalamus4.44 ± 0.67
Temporal Lobe3.37 ± 0.98
Thalamus3.3 ± 0.8
White Matter4.75 ± 0.78
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00029397 26 772 797 DAPCSASSELSGPSTPLHTSSPVQGK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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