AutismKB 2.0

Annotation Detail for AHCYL2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:AHCYL2 ( ADOHCYASE3,FLJ21719,KIAA0828 )
Gene Full Name: adenosylhomocysteinase-like 2
Band: 7q32.1
Quick LinksEntrez ID:23382; OMIM: NA; Uniprot ID:SAHH3_HUMAN; ENSEMBL ID: ENSG00000158467; HGNC ID: 22204
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst2 / 6231932
fetus18 / 56401231
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult70 / 193912136
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor5 / 9417853
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor4 / 11424635
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor5 / 26384518
glioma2 / 10688318
head and neck tumor3 / 13630222
kidney tumor2 / 6895929
leukemia0 / 958420 
liver tumor2 / 9635920
lung tumor7 / 10312767
lymphoma3 / 7175541
non-neoplasia1 / 9725010
normal130 / 336030738
ovarian tumor0 / 766820 
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer0 / 1026800 
retinoblastoma1 / 4635621
skin tumor3 / 12494924
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood0 / 1234780 
bone2 / 7165527
bone marrow0 / 488010 
brain50 / 110098945
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue10 / 21572246
esophagus0 / 202090 
eye12 / 21105456
heart3 / 8962633
intestine24 / 234472102
kidney12 / 21177756
larynx0 / 241450 
liver4 / 20774319
lung15 / 33697444
lymph2 / 4427045
lymph node3 / 9161032
mammary gland5 / 15327132
mouth1 / 6705214
muscle4 / 10771537
nerve0 / 157680 
ovary1 / 1020519
pancreas8 / 21481237
parathyroid1 / 2053948
pharynx1 / 4132824
pituitary gland1 / 1658560
placenta5 / 28082517
prostate0 / 1893450 
salivary gland0 / 201550 
skin9 / 21057442
spleen1 / 5395218
stomach2 / 9661920
testis11 / 33044233
thymus1 / 8113112
thyroid2 / 4747342
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus4 / 23287817
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 215672_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.15
Adipocyte4.85
AdrenalCortex5.2
Adrenalgland4.1
Amygdala5.05
Appendix5.05
AtrioventricularNode5.35
BDCA4+_DentriticCells5.05
Bonemarrow5.3
BronchialEpithelialCells4.95
CD105+_Endothelial4.85
CD14+_Monocytes5.1
CD19+_BCells(neg._sel.)4.9
CD33+_Myeloid6.3
CD34+6.2
CD4+_Tcells5.25
CD56+_NKCells5.8
CD71+_EarlyErythroid4.5
CD8+_Tcells4.5
CardiacMyocytes6
Caudatenucleus4.35
Cerebellum6
CerebellumPeduncles5.5
CiliaryGanglion4.6
CingulateCortex6.7
Colorectaladenocarcinoma4.9
DorsalRootGanglion3.75
FetalThyroid4.65
Fetalbrain4.9
Fetalliver4.15
Fetallung4.1
GlobusPallidus3.85
Heart6.15
Hypothalamus5.45
Kidney4.1
Leukemia_chronicMyelogenousK-5625.1
Leukemia_promyelocytic-HL-604.25
Leukemialymphoblastic(MOLT-4)3.85
Liver6.35
Lung5.4
Lymphnode4.05
Lymphoma_burkitts(Daudi)6.1
Lymphoma_burkitts(Raji)6.7
MedullaOblongata4.55
OccipitalLobe4.45
OlfactoryBulb4.05
Ovary3.25
Pancreas3.9
PancreaticIslet5.2
ParietalLobe5.15
Pituitary5.85
Placenta4.9
Pons7.55
PrefrontalCortex6.45
Prostate5.65
Salivarygland3.9
SkeletalMuscle5.6
Skin3.7
SmoothMuscle5.5
Spinalcord5.4
SubthalamicNucleus5.15
SuperiorCervicalGanglion6.55
TemporalLobe4.45
Testis4.25
TestisGermCell4.65
TestisIntersitial12.15
TestisLeydigCell4.8
TestisSeminiferousTubule4.35
Thalamus5
Thymus3.9
Thyroid6.05
Tongue4.85
Tonsil4.7
Trachea4.05
TrigeminalGanglion7.65
Uterus3.95
UterusCorpus11.15
WholeBlood5.35
Wholebrain4.1
colon6.75
pineal_day15
pineal_night26.76
retina6.075
small_intestine4.65
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P252075
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.65 ± 0.43
Basal Forebrain7.23 ± 0.23
Basal Part of Pons6.66 ± 0.3
Cerebellar Cortex6.44 ± 0.26
Cerebellar Nuclei7.34 ± 0.33
Claustrum6.46 ± 0.61
Epithalamus6.74 ± 0.56
Frontal Lobe6.92 ± 0.39
Globus Pallidus7.53 ± 0.21
Hypothalamus6.75 ± 0.32
Insula6.85 ± 0.41
Limbic Lobe6.85 ± 0.34
Mesencephalon6.85 ± 0.5
Myelencephalon6.85 ± 0.42
Occipital Lobe7.17 ± 0.49
Parietal Lobe6.89 ± 0.3
Pontine Tegmentum6.97 ± 0.52
Striatum7.14 ± 0.31
Subthalamus7.15 ± 0.3
Temporal Lobe6.74 ± 0.32
Thalamus6.88 ± 0.38
White Matter6.53 ± 0.25
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
4631427C17RikCBCerebellum20.63
30.53
4631427C17RikCTXCerebral cortex17.07
13.48
4631427C17RikHIPHippocampal region70.08
91.79
4631427C17RikHPFHippocampal formation51.38
74.47
4631427C17RikHYHypothalamus11.64
10.44
4631427C17RikLSXLateral septal complex7.16
7.07
4631427C17RikMBMidbrain17.53
19.91
4631427C17RikMYMedulla29.91
42.93
4631427C17RikOLFOlfactory bulb24.34
21.35
4631427C17RikPPons19.42
25.08
4631427C17RikPALPallidum13.61
14.26
4631427C17RikRHPRetrohippocampal region21.16
19.16
4631427C17RiksAMYStriatum-like amygdalar nuclei10.19
8.39
4631427C17RikSTRStriatum7.12
6.1
4631427C17RikSTRdStriatum dorsal region4.28
3.78
4631427C17RikSTRvStriatum ventral region14.37
10.58
4631427C17RikTHThalamus20.24
21.49
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00002770 13 283 295 GESEDDFWWCIDR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved