AutismKB 2.0

Annotation Detail for NUDCD3


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Basic Information Top
Gene Symbol:NUDCD3 ( KIAA1068,NudCL )
Gene Full Name: NudC domain containing 3
Band: 7p13
Quick LinksEntrez ID:23386; OMIM: 610296; Uniprot ID:NUDC3_HUMAN; ENSEMBL ID: ENSG00000015676; HGNC ID: 22208
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body10 / 70761141
blastocyst8 / 62319128
fetus38 / 56401267
neonate2 / 3109764
infant2 / 2362084
juvenile4 / 5555671
adult204 / 1939121105
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor3 / 12794234
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor5 / 34366145
chondrosarcoma15 / 82823181
colorectal tumor16 / 114246140
esophageal tumor0 / 172900 
gastrointestinal tumor9 / 11936975
germ cell tumor13 / 26384549
glioma35 / 106883327
head and neck tumor9 / 13630266
kidney tumor9 / 68959130
leukemia6 / 9584262
liver tumor2 / 9635920
lung tumor11 / 103127106
lymphoma14 / 71755195
non-neoplasia5 / 9725051
normal287 / 336030785
ovarian tumor13 / 76682169
pancreatic tumor15 / 104616143
primitive neuroectodermal tumor of the CNS18 / 125680143
prostate cancer7 / 10268068
retinoblastoma4 / 4635686
skin tumor16 / 124949128
soft tissue/muscle tissue tumor28 / 125191223
uterine tumor9 / 9025799
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland5 / 33197150
ascites4 / 4001599
bladder1 / 2975733
blood5 / 12347840
bone10 / 71655139
bone marrow2 / 4880140
brain167 / 1100989151
cervix9 / 48171186
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue22 / 215722101
esophagus0 / 202090 
eye21 / 21105499
heart4 / 8962644
intestine19 / 23447281
kidney13 / 21177761
larynx2 / 2414582
liver10 / 20774348
lung32 / 33697494
lymph8 / 44270180
lymph node10 / 91610109
mammary gland5 / 15327132
mouth5 / 6705274
muscle34 / 107715315
nerve3 / 15768190
ovary16 / 102051156
pancreas24 / 214812111
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta26 / 28082592
prostate10 / 18934552
salivary gland2 / 2015599
skin25 / 210574118
spleen2 / 5395237
stomach5 / 9661951
testis23 / 33044269
thymus1 / 8113112
thyroid2 / 4747342
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord2 / 13680146
uterus25 / 232878107
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 201270_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts112.55
Adipocyte13.7
AdrenalCortex16.7
Adrenalgland23.3
Amygdala78.05
Appendix12.3
AtrioventricularNode10.25
BDCA4+_DentriticCells23.45
Bonemarrow12.95
BronchialEpithelialCells24.1
CD105+_Endothelial23.6
CD14+_Monocytes18.6
CD19+_BCells(neg._sel.)23.35
CD33+_Myeloid24
CD34+59.9
CD4+_Tcells27.8
CD56+_NKCells75.95
CD71+_EarlyErythroid40.85
CD8+_Tcells41.3
CardiacMyocytes20.4
Caudatenucleus70.3
Cerebellum65.9
CerebellumPeduncles96.85
CiliaryGanglion10
CingulateCortex79.45
Colorectaladenocarcinoma37.15
DorsalRootGanglion11.35
FetalThyroid21.25
Fetalbrain92.8
Fetalliver10.45
Fetallung19.75
GlobusPallidus84.1
Heart40.1
Hypothalamus127.15
Kidney16.7
Leukemia_chronicMyelogenousK-56216.15
Leukemia_promyelocytic-HL-6011.65
Leukemialymphoblastic(MOLT-4)10.6
Liver20.45
Lung60.05
Lymphnode18.15
Lymphoma_burkitts(Daudi)65.35
Lymphoma_burkitts(Raji)35.4
MedullaOblongata104.25
OccipitalLobe54.2
OlfactoryBulb17.65
Ovary8.65
Pancreas15.35
PancreaticIslet28.9
ParietalLobe71.15
Pituitary16.45
Placenta22.9
Pons65.2
PrefrontalCortex323.05
Prostate100.2
Salivarygland10.15
SkeletalMuscle19.75
Skin11.3
SmoothMuscle18.1
Spinalcord44.35
SubthalamicNucleus113.3
SuperiorCervicalGanglion14
TemporalLobe108.05
Testis38.1
TestisGermCell15.5
TestisIntersitial22.8
TestisLeydigCell17.25
TestisSeminiferousTubule14
Thalamus75.15
Thymus27.3
Thyroid31.45
Tongue13.6
Tonsil16.5
Trachea12.55
TrigeminalGanglion20.4
Uterus59.8
UterusCorpus13.1
WholeBlood15.45
Wholebrain221.8
colon13
pineal_day35.8
pineal_night37.16
retina32.4
small_intestine12.55
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P218056
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.3 ± 0.42
Basal Forebrain5.87 ± 0.15
Basal Part of Pons6.3 ± 0.43
Cerebellar Cortex5.79 ± 0.31
Cerebellar Nuclei5.68 ± 0.2
Claustrum6.56 ± 0.53
Epithalamus5.58 ± 0.23
Frontal Lobe5.91 ± 0.4
Globus Pallidus5.67 ± 0.41
Hypothalamus5.92 ± 0.44
Insula5.91 ± 0.38
Limbic Lobe6.3 ± 0.43
Mesencephalon5.9 ± 0.44
Myelencephalon6.08 ± 0.42
Occipital Lobe6.35 ± 0.4
Parietal Lobe6.17 ± 0.43
Pontine Tegmentum6.03 ± 0.45
Striatum6.31 ± 0.41
Subthalamus5.4 ± 0.15
Temporal Lobe6.18 ± 0.42
Thalamus5.93 ± 0.43
White Matter5.04 ± 0.77
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Nudcd3CBCerebellum24.29
29.49
Nudcd3CTXCerebral cortex97.71
85.28
Nudcd3HIPHippocampal region41.43
71.93
Nudcd3HPFHippocampal formation56.68
72.97
Nudcd3HYHypothalamus30.27
25.96
Nudcd3LSXLateral septal complex31.19
24.6
Nudcd3MBMidbrain42.64
40.78
Nudcd3MYMedulla45.98
54.37
Nudcd3OLFOlfactory bulb60.37
52.26
Nudcd3PPons44.06
48.81
Nudcd3PALPallidum44.52
44.91
Nudcd3RHPRetrohippocampal region85.55
78.72
Nudcd3sAMYStriatum-like amygdalar nuclei67.77
55.49
Nudcd3STRStriatum48.21
37.17
Nudcd3STRdStriatum dorsal region50.39
38.92
Nudcd3STRvStriatum ventral region41.45
29.98
Nudcd3THThalamus49.05
43.38
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00066608 15 188 202 ENYTWSQDYTDLEVR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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