AutismKB 2.0

Annotation Detail for ADNP


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Basic Information Top
Gene Symbol:ADNP ( ADNP1,KIAA0784 )
Gene Full Name: activity-dependent neuroprotector homeobox
Band: 20q13.13
Quick LinksEntrez ID:23394; OMIM: 611386; Uniprot ID:ADNP_HUMAN; ENSEMBL ID: ENSG00000101126; HGNC ID: 15766
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst11 / 62319176
fetus65 / 564012115
neonate2 / 3109764
infant1 / 2362042
juvenile1 / 5555617
adult207 / 1939121106
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor18 / 94178191
cervical tumor2 / 3436658
chondrosarcoma3 / 8282336
colorectal tumor32 / 114246280
esophageal tumor2 / 17290115
gastrointestinal tumor17 / 119369142
germ cell tumor44 / 263845166
glioma3 / 10688328
head and neck tumor17 / 136302124
kidney tumor5 / 6895972
leukemia12 / 95842125
liver tumor3 / 9635931
lung tumor4 / 10312738
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal273 / 336030781
ovarian tumor4 / 7668252
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer4 / 10268038
retinoblastoma3 / 4635664
skin tumor2 / 12494916
soft tissue/muscle tissue tumor12 / 12519195
uterine tumor15 / 90257166
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites11 / 40015274
bladder1 / 2975733
blood7 / 12347856
bone5 / 7165569
bone marrow3 / 4880161
brain72 / 110098965
cervix2 / 4817141
connective tissue5 / 14925533
ear3 / 16212185
embryonic tissue22 / 215722101
esophagus2 / 2020998
eye15 / 21105471
heart2 / 8962622
intestine38 / 234472162
kidney25 / 211777118
larynx6 / 24145248
liver8 / 20774338
lung21 / 33697462
lymph0 / 442700 
lymph node32 / 91610349
mammary gland39 / 153271254
mouth9 / 67052134
muscle2 / 10771518
nerve2 / 15768126
ovary4 / 10205139
pancreas11 / 21481251
parathyroid3 / 20539146
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta12 / 28082542
prostate13 / 18934568
salivary gland0 / 201550 
skin7 / 21057433
spleen3 / 5395255
stomach7 / 9661972
testis47 / 330442142
thymus10 / 81131123
thyroid3 / 4747363
tonsil0 / 169990 
trachea6 / 52413114
umbilical cord0 / 136800 
uterus27 / 232878115
vascular10 / 51780193
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 201773_at
Cell line Expression level Expression bar
721_B_lymphoblasts300.4
Adipocyte30.35
AdrenalCortex20.55
Adrenalgland20.15
Amygdala122.75
Appendix30.65
AtrioventricularNode12.85
BDCA4+_DentriticCells100.6
Bonemarrow22.45
BronchialEpithelialCells135.9
CD105+_Endothelial64.1
CD14+_Monocytes44.65
CD19+_BCells(neg._sel.)106.75
CD33+_Myeloid59.75
CD34+286.5
CD4+_Tcells148.9
CD56+_NKCells134.65
CD71+_EarlyErythroid33.9
CD8+_Tcells111.1
CardiacMyocytes40.5
Caudatenucleus35.15
Cerebellum38.05
CerebellumPeduncles42.8
CiliaryGanglion17
CingulateCortex26.15
Colorectaladenocarcinoma109
DorsalRootGanglion16.5
FetalThyroid33.35
Fetalbrain285.05
Fetalliver55.25
Fetallung78
GlobusPallidus15.25
Heart6.8
Hypothalamus69.5
Kidney18.25
Leukemia_chronicMyelogenousK-56232.1
Leukemia_promyelocytic-HL-60137.7
Leukemialymphoblastic(MOLT-4)197.2
Liver16.25
Lung39.15
Lymphnode67.7
Lymphoma_burkitts(Daudi)81.6
Lymphoma_burkitts(Raji)207.55
MedullaOblongata29.35
OccipitalLobe51.05
OlfactoryBulb36.25
Ovary13.7
Pancreas49.6
PancreaticIslet65.5
ParietalLobe27.75
Pituitary81.65
Placenta143.05
Pons14.85
PrefrontalCortex122.05
Prostate98.4
Salivarygland51.3
SkeletalMuscle13.2
Skin17.45
SmoothMuscle62.7
Spinalcord43.2
SubthalamicNucleus27.35
SuperiorCervicalGanglion24
TemporalLobe27.45
Testis42.55
TestisGermCell111.25
TestisIntersitial58.3
TestisLeydigCell67.4
TestisSeminiferousTubule51.15
Thalamus23.25
Thymus111
Thyroid161.55
Tongue21.3
Tonsil58
Trachea37.2
TrigeminalGanglion20.25
Uterus131.35
UterusCorpus33.1
WholeBlood162.6
Wholebrain57.8
colon89.5
pineal_day94.76
pineal_night145.62
retina89.75
small_intestine68
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_10358_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.51 ± 0.39
Basal Forebrain9.19 ± 0.13
Basal Part of Pons8.83 ± 0.22
Cerebellar Cortex9.21 ± 0.38
Cerebellar Nuclei8.94 ± 0.23
Claustrum9.54 ± 0.49
Epithalamus9.28 ± 0.16
Frontal Lobe9.01 ± 0.31
Globus Pallidus9.14 ± 0.16
Hypothalamus9 ± 0.27
Insula9.14 ± 0.28
Limbic Lobe9.32 ± 0.36
Mesencephalon9.17 ± 0.25
Myelencephalon9.17 ± 0.37
Occipital Lobe9.45 ± 0.38
Parietal Lobe9.14 ± 0.3
Pontine Tegmentum9.17 ± 0.28
Striatum9.26 ± 0.3
Subthalamus8.73 ± 0.21
Temporal Lobe9.15 ± 0.28
Thalamus9.22 ± 0.24
White Matter9.68 ± 0.38
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
ADNP_HUMAN_1 13 1 13 MFQLPVNNLGSLR PRIDE
ADNP_HUMAN_3 11 3 13 QLPVNNLGSLR PRIDE
PAp00064645 24 573 596 DAPAESVAYHAQNNPPVPPKPQPK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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