AutismKB 2.0

Annotation Detail for NCS1


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Basic Information Top
Gene Symbol:NCS1 ( DKFZp761L1223,FLUP,FREQ )
Gene Full Name: neuronal calcium sensor 1
Band: 9q34.11
Quick LinksEntrez ID:23413; OMIM: 603315; Uniprot ID:NCS1_HUMAN; ENSEMBL ID: ENSG00000107130; HGNC ID: 3953
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body8 / 70761113
blastocyst5 / 6231980
fetus40 / 56401270
neonate0 / 310970 
infant3 / 23620127
juvenile2 / 5555635
adult96 / 193912149
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma1 / 1747557
breast (mammary gland) tumor9 / 9417895
cervical tumor2 / 3436658
chondrosarcoma2 / 8282324
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor17 / 26384564
glioma16 / 106883149
head and neck tumor3 / 13630222
kidney tumor4 / 6895958
leukemia1 / 9584210
liver tumor1 / 9635910
lung tumor6 / 10312758
lymphoma0 / 717550 
non-neoplasia11 / 97250113
normal249 / 336030774
ovarian tumor12 / 76682156
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS24 / 125680190
prostate cancer4 / 10268038
retinoblastoma4 / 4635686
skin tumor6 / 12494948
soft tissue/muscle tissue tumor5 / 12519139
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites1 / 4001524
bladder1 / 2975733
blood0 / 1234780 
bone1 / 7165513
bone marrow0 / 488010 
brain187 / 1100989169
cervix2 / 4817141
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue14 / 21572264
esophagus0 / 202090 
eye19 / 21105490
heart5 / 8962655
intestine9 / 23447238
kidney11 / 21177751
larynx0 / 241450 
liver1 / 2077434
lung10 / 33697429
lymph0 / 442700 
lymph node0 / 916100 
mammary gland9 / 15327158
mouth1 / 6705214
muscle0 / 1077150 
nerve4 / 15768253
ovary14 / 102051137
pancreas10 / 21481246
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate7 / 18934536
salivary gland2 / 2015599
skin10 / 21057447
spleen0 / 539520 
stomach2 / 9661920
testis2 / 3304426
thymus0 / 811310 
thyroid2 / 4747342
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus13 / 23287855
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218266_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts4.9
Adipocyte4.9
AdrenalCortex7.3
Adrenalgland4.7
Amygdala37.15
Appendix5.35
AtrioventricularNode4.05
BDCA4+_DentriticCells5.1
Bonemarrow5.15
BronchialEpithelialCells5.35
CD105+_Endothelial5.5
CD14+_Monocytes5.65
CD19+_BCells(neg._sel.)5.45
CD33+_Myeloid6.6
CD34+6.4
CD4+_Tcells4.7
CD56+_NKCells6.1
CD71+_EarlyErythroid4.85
CD8+_Tcells4
CardiacMyocytes9.45
Caudatenucleus4.75
Cerebellum12.25
CerebellumPeduncles9.6
CiliaryGanglion3.7
CingulateCortex7.9
Colorectaladenocarcinoma4.95
DorsalRootGanglion4.15
FetalThyroid5.3
Fetalbrain5.3
Fetalliver4.45
Fetallung4.35
GlobusPallidus3.95
Heart6.9
Hypothalamus10.7
Kidney4.45
Leukemia_chronicMyelogenousK-5624.8
Leukemia_promyelocytic-HL-604.45
Leukemialymphoblastic(MOLT-4)4.3
Liver8.55
Lung5.85
Lymphnode4.1
Lymphoma_burkitts(Daudi)6.8
Lymphoma_burkitts(Raji)7.45
MedullaOblongata13.15
OccipitalLobe5.7
OlfactoryBulb3.95
Ovary7.6
Pancreas4.45
PancreaticIslet5.5
ParietalLobe7.05
Pituitary6.6
Placenta5.2
Pons6.6
PrefrontalCortex30.75
Prostate8.25
Salivarygland5.55
SkeletalMuscle6.25
Skin4
SmoothMuscle6.3
Spinalcord5.85
SubthalamicNucleus7.75
SuperiorCervicalGanglion9
TemporalLobe9.45
Testis4.55
TestisGermCell4.4
TestisIntersitial4.5
TestisLeydigCell5.3
TestisSeminiferousTubule4.75
Thalamus5.5
Thymus4.15
Thyroid7
Tongue6.6
Tonsil5.3
Trachea4.2
TrigeminalGanglion5.75
Uterus5.65
UterusCorpus4.85
WholeBlood5.7
Wholebrain51.25
colon5.3
pineal_day5.96
pineal_night5.86
retina7.2
small_intestine4.55
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P217049
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala11.74 ± 0.48
Basal Forebrain10.88 ± 0.19
Basal Part of Pons11.22 ± 0.31
Cerebellar Cortex10.81 ± 0.2
Cerebellar Nuclei10.52 ± 0.45
Claustrum11.28 ± 0.48
Epithalamus10.27 ± 0.31
Frontal Lobe11.07 ± 0.47
Globus Pallidus10.37 ± 0.59
Hypothalamus10.5 ± 0.39
Insula11.26 ± 0.39
Limbic Lobe11.66 ± 0.43
Mesencephalon10.86 ± 0.5
Myelencephalon11.11 ± 0.4
Occipital Lobe11.55 ± 0.47
Parietal Lobe11.34 ± 0.46
Pontine Tegmentum11.2 ± 0.39
Striatum10.98 ± 0.61
Subthalamus10.67 ± 0.18
Temporal Lobe11.38 ± 0.39
Thalamus11.3 ± 0.39
White Matter9.06 ± 0.47
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
FreqCBCerebellum56.19
68.19
FreqCTXCerebral cortex100
100
FreqHIPHippocampal region69.25
100
FreqHPFHippocampal formation84.21
100
FreqHYHypothalamus76.89
82.9
FreqLSXLateral septal complex84.48
69.39
FreqMBMidbrain76.36
94.78
FreqMYMedulla90.21
100
FreqOLFOlfactory bulb100
100
FreqPPons76.21
100
FreqPALPallidum78.41
96.14
FreqRHPRetrohippocampal region100
100
FreqsAMYStriatum-like amygdalar nuclei100
100
FreqSTRStriatum81.32
70.43
FreqSTRdStriatum dorsal region72.38
63.32
FreqSTRvStriatum ventral region87.84
69.33
FreqTHThalamus100
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00505799 11 8 18 LKPEVVEELTR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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