Annotation Detail for KCNH3
Basic Information Top
| Gene Symbol: | KCNH3 ( BEC1,ELK2,KIAA1282,Kv12.2 ) |
|---|---|
| Gene Full Name: | potassium voltage-gated channel, subfamily H (eag-related), member 3 |
| Band: | 12q13.12 |
| Quick Links | Entrez ID:23416; OMIM: 604527; Uniprot ID:KCNH3_HUMAN; ENSEMBL ID: ENSG00000135519; HGNC ID: 6252 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.64064
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 0 / 70761 | 0 | |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 3 / 564012 | 5 |  |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 8 / 1939121 | 4 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 0 / 94178 | 0 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 0 / 82823 | 0 | |
| colorectal tumor | 0 / 114246 | 0 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 0 / 119369 | 0 | |
| germ cell tumor | 0 / 263845 | 0 | |
| glioma | 2 / 106883 | 18 |  |
| head and neck tumor | 0 / 136302 | 0 | |
| kidney tumor | 0 / 68959 | 0 | |
| leukemia | 1 / 95842 | 10 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 7 / 103127 | 67 |  |
| lymphoma | 1 / 71755 | 13 | |
| non-neoplasia | 2 / 97250 | 20 | |
| normal | 15 / 3360307 | 4 | |
| ovarian tumor | 0 / 76682 | 0 | |
| pancreatic tumor | 0 / 104616 | 0 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 3 / 46356 | 64 | |
| skin tumor | 0 / 124949 | 0 | |
| soft tissue/muscle tissue tumor | 0 / 125191 | 0 | |
| uterine tumor | 2 / 90257 | 22 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 0 / 29757 | 0 | |
| blood | 0 / 123478 | 0 | |
| bone | 0 / 71655 | 0 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 9 / 1100989 | 8 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 0 / 149255 | 0 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 0 / 215722 | 0 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 3 / 211054 | 14 | |
| heart | 0 / 89626 | 0 | |
| intestine | 0 / 234472 | 0 | |
| kidney | 0 / 211777 | 0 | |
| larynx | 0 / 24145 | 0 | |
| liver | 0 / 207743 | 0 | |
| lung | 8 / 336974 | 23 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 1 / 91610 | 10 | |
| mammary gland | 1 / 153271 | 6 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 0 / 107715 | 0 | |
| nerve | 1 / 15768 | 63 | |
| ovary | 0 / 102051 | 0 | |
| pancreas | 0 / 214812 | 0 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 1 / 16585 | 60 | |
| placenta | 0 / 280825 | 0 | |
| prostate | 0 / 189345 | 0 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 0 / 210574 | 0 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 0 / 96619 | 0 | |
| testis | 0 / 330442 | 0 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 2 / 232878 | 8 | |
| vascular | 0 / 51780 | 0 |
Microarray in - Probe name: CUST_1499_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 4.78 ± 0.43 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 3.4 ± 0.42 | |
| Basal Part of Pons | 3.65 ± 0.66 | |
| Cerebellar Cortex | 3.42 ± 0.5 | |
| Cerebellar Nuclei | 3.47 ± 0.59 | |
| Claustrum | 4.03 ± 0.9 | |
| Epithalamus | 3.47 ± 0.73 | |
| Frontal Lobe | 4.13 ± 0.78 | |
| Globus Pallidus | 2.2 ± 1.19 | |
| Hypothalamus | 3.52 ± 0.63 | |
| Insula | 4.24 ± 0.64 | |
| Limbic Lobe | 4.44 ± 0.71 | |
| Mesencephalon | 3.82 ± 0.85 | |
| Myelencephalon | 3.9 ± 0.73 | |
| Occipital Lobe | 3.78 ± 0.67 | |
| Parietal Lobe | 4.12 ± 0.71 | |
| Pontine Tegmentum | 3.95 ± 0.7 | |
| Striatum | 3.97 ± 0.88 | |
| Subthalamus | 4.3 ± 2.02 | |
| Temporal Lobe | 4.34 ± 0.62 | |
| Thalamus | 3.38 ± 0.81 | |
| White Matter | 1.91 ± 0.88 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Kcnh3 | CB | Cerebellum | 0.49 | |
| 0.6 | | |||
| Kcnh3 | CTX | Cerebral cortex | 18.02 | |
| 14.1 | | |||
| Kcnh3 | HIP | Hippocampal region | 6.56 | |
| 8.83 | | |||
| Kcnh3 | HPF | Hippocampal formation | 7.17 | |
| 7.72 | | |||
| Kcnh3 | HY | Hypothalamus | 0.16 | |
| 0.14 | | |||
| Kcnh3 | LSX | Lateral septal complex | 1.34 | |
| 1.76 | | |||
| Kcnh3 | MB | Midbrain | 0.58 | |
| 0.67 | | |||
| Kcnh3 | MY | Medulla | 0.37 | |
| 0.44 | | |||
| Kcnh3 | OLF | Olfactory bulb | 17.7 | |
| 17.01 | | |||
| Kcnh3 | P | Pons | 0.13 | |
| 0.18 | | |||
| Kcnh3 | PAL | Pallidum | 0.54 | |
| 0.52 | | |||
| Kcnh3 | RHP | Retrohippocampal region | 7.86 | |
| 6.42 | | |||
| Kcnh3 | sAMY | Striatum-like amygdalar nuclei | 3.11 | |
| 2.27 | | |||
| Kcnh3 | STR | Striatum | 2.89 | |
| 2.2 | | |||
| Kcnh3 | STRd | Striatum dorsal region | 2.95 | |
| 2.04 | | |||
| Kcnh3 | STRv | Striatum ventral region | 3.21 | |
| 2.81 | | |||
| Kcnh3 | TH | Thalamus | 0.36 | |
| 0.34 | |