AutismKB 2.0

Annotation Detail for GCAT


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Basic Information Top
Gene Symbol:GCAT ( KBL,MGC23053 )
Gene Full Name: glycine C-acetyltransferase
Band: 22q13.1
Quick LinksEntrez ID:23464; OMIM: 607422; Uniprot ID:KBL_HUMAN; ENSEMBL ID: ENSG00000100116; HGNC ID: 4188
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst3 / 6231948
fetus7 / 56401212
neonate0 / 310970 
infant2 / 2362084
juvenile0 / 555560 
adult33 / 193912117
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor5 / 26384518
glioma3 / 10688328
head and neck tumor3 / 13630222
kidney tumor1 / 6895914
leukemia3 / 9584231
liver tumor7 / 9635972
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal79 / 336030723
ovarian tumor1 / 7668213
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS10 / 12568079
prostate cancer0 / 1026800 
retinoblastoma2 / 4635643
skin tumor11 / 12494988
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites1 / 4001524
bladder0 / 297570 
blood3 / 12347824
bone2 / 7165527
bone marrow0 / 488010 
brain31 / 110098928
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue6 / 21572227
esophagus0 / 202090 
eye7 / 21105433
heart1 / 8962611
intestine11 / 23447246
kidney7 / 21177733
larynx0 / 241450 
liver9 / 20774343
lung9 / 33697426
lymph0 / 442700 
lymph node3 / 9161032
mammary gland3 / 15327119
mouth0 / 670520 
muscle0 / 1077150 
nerve1 / 1576863
ovary1 / 1020519
pancreas9 / 21481241
parathyroid5 / 20539243
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate9 / 18934547
salivary gland1 / 2015549
skin11 / 21057452
spleen0 / 539520 
stomach5 / 9661951
testis7 / 33044221
thymus1 / 8113112
thyroid3 / 4747363
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus2 / 2328788
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 36475_at
Cell line Expression level Expression bar
721_B_lymphoblasts9.15
Adipocyte6.75
AdrenalCortex7.3
Adrenalgland5.65
Amygdala7.25
Appendix6.55
AtrioventricularNode4.9
BDCA4+_DentriticCells6.9
Bonemarrow6.75
BronchialEpithelialCells7.4
CD105+_Endothelial6.85
CD14+_Monocytes7.15
CD19+_BCells(neg._sel.)6.65
CD33+_Myeloid7.4
CD34+8.8
CD4+_Tcells7.3
CD56+_NKCells8
CD71+_EarlyErythroid7.75
CD8+_Tcells4.65
CardiacMyocytes8.35
Caudatenucleus6.05
Cerebellum5.55
CerebellumPeduncles11.7
CiliaryGanglion4.55
CingulateCortex7.3
Colorectaladenocarcinoma6.75
DorsalRootGanglion5
FetalThyroid6.55
Fetalbrain6.75
Fetalliver5.85
Fetallung6.05
GlobusPallidus5.05
Heart28.65
Hypothalamus8
Kidney6.4
Leukemia_chronicMyelogenousK-5627.7
Leukemia_promyelocytic-HL-605.9
Leukemialymphoblastic(MOLT-4)6
Liver60.85
Lung7.5
Lymphnode5.75
Lymphoma_burkitts(Daudi)8.5
Lymphoma_burkitts(Raji)9.5
MedullaOblongata6.25
OccipitalLobe6.1
OlfactoryBulb5.35
Ovary4.35
Pancreas9.65
PancreaticIslet7.25
ParietalLobe7.3
Pituitary7.9
Placenta5.85
Pons6.1
PrefrontalCortex8.65
Prostate16.5
Salivarygland5.35
SkeletalMuscle8.05
Skin4.95
SmoothMuscle7.85
Spinalcord7.25
SubthalamicNucleus6
SuperiorCervicalGanglion7.45
TemporalLobe7.25
Testis8.05
TestisGermCell5.75
TestisIntersitial5.65
TestisLeydigCell6.3
TestisSeminiferousTubule5.8
Thalamus6.55
Thymus5.45
Thyroid10.2
Tongue6.45
Tonsil6.5
Trachea5.7
TrigeminalGanglion6.45
Uterus5.3
UterusCorpus5.9
WholeBlood7.45
Wholebrain7.4
colon6.7
pineal_day7.44
pineal_night6.96
retina8.275
small_intestine6.55
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_7707_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.38 ± 0.4
Basal Forebrain5.28 ± 0.39
Basal Part of Pons5.41 ± 0.39
Cerebellar Cortex5.24 ± 0.39
Cerebellar Nuclei5.3 ± 0.35
Claustrum5.27 ± 0.5
Epithalamus4.91 ± 0.43
Frontal Lobe5.28 ± 0.38
Globus Pallidus5.85 ± 0.2
Hypothalamus5.21 ± 0.35
Insula5.07 ± 0.39
Limbic Lobe5.53 ± 0.44
Mesencephalon5.46 ± 0.5
Myelencephalon5.37 ± 0.39
Occipital Lobe5.62 ± 0.42
Parietal Lobe5.36 ± 0.35
Pontine Tegmentum5.33 ± 0.31
Striatum5.33 ± 0.4
Subthalamus5.11 ± 0.04
Temporal Lobe5.27 ± 0.35
Thalamus5.45 ± 0.28
White Matter5.37 ± 0.44
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
GcatCBCerebellum1.88
3.1
GcatCTXCerebral cortex6.7
6.22
GcatHIPHippocampal region4.72
5.3
GcatHPFHippocampal formation4.08
4.05
GcatHYHypothalamus0.49
0.61
GcatLSXLateral septal complex0.15
0.31
GcatMBMidbrain1.39
2.52
GcatMYMedulla1.7
2.13
GcatOLFOlfactory bulb5.85
6.65
GcatPPons1.94
2.99
GcatPALPallidum0.44
0.52
GcatRHPRetrohippocampal region3.08
2.38
GcatsAMYStriatum-like amygdalar nuclei1.58
1.3
GcatSTRStriatum1.43
1.56
GcatSTRdStriatum dorsal region0.99
1.08
GcatSTRvStriatum ventral region3.72
4.01
GcatTHThalamus1.92
1.71
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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