AutismKB 2.0

Annotation Detail for NPTXR


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Basic Information Top
Gene Symbol:NPTXR ( NPR )
Gene Full Name: neuronal pentraxin receptor
Band: 22q13.1
Quick LinksEntrez ID:23467; OMIM: 609474; Uniprot ID:NPTXR_HUMAN; ENSEMBL ID: ENSG00000221890; HGNC ID: 7954
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst2 / 6231932
fetus33 / 56401258
neonate0 / 310970 
infant2 / 2362084
juvenile2 / 5555635
adult49 / 193912125
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor9 / 9417895
cervical tumor2 / 3436658
chondrosarcoma3 / 8282336
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor2 / 2638457
glioma11 / 106883102
head and neck tumor1 / 1363027
kidney tumor3 / 6895943
leukemia0 / 958420 
liver tumor2 / 9635920
lung tumor6 / 10312758
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal148 / 336030744
ovarian tumor2 / 7668226
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS9 / 12568071
prostate cancer0 / 1026800 
retinoblastoma1 / 4635621
skin tumor1 / 1249498
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone4 / 7165555
bone marrow0 / 488010 
brain132 / 1100989119
cervix2 / 4817141
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye6 / 21105428
heart1 / 8962611
intestine1 / 2344724
kidney3 / 21177714
larynx0 / 241450 
liver2 / 2077439
lung7 / 33697420
lymph0 / 442700 
lymph node0 / 916100 
mammary gland9 / 15327158
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary2 / 10205119
pancreas4 / 21481218
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin4 / 21057418
spleen1 / 5395218
stomach0 / 966190 
testis3 / 3304429
thymus0 / 811310 
thyroid2 / 4747342
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus3 / 23287812
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 213040_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts8.9
Adipocyte7.55
AdrenalCortex9.05
Adrenalgland7.05
Amygdala808.1
Appendix8.1
AtrioventricularNode6.25
BDCA4+_DentriticCells6.9
Bonemarrow13.1
BronchialEpithelialCells6.75
CD105+_Endothelial7.15
CD14+_Monocytes7.75
CD19+_BCells(neg._sel.)8.1
CD33+_Myeloid9.4
CD34+8.45
CD4+_Tcells10.65
CD56+_NKCells9.6
CD71+_EarlyErythroid7.1
CD8+_Tcells10.4
CardiacMyocytes11.7
Caudatenucleus14.7
Cerebellum60
CerebellumPeduncles73.95
CiliaryGanglion8.5
CingulateCortex290.4
Colorectaladenocarcinoma13.1
DorsalRootGanglion6.5
FetalThyroid8
Fetalbrain143.75
Fetalliver6.65
Fetallung5.9
GlobusPallidus117.55
Heart33.15
Hypothalamus79.6
Kidney6.75
Leukemia_chronicMyelogenousK-5628.55
Leukemia_promyelocytic-HL-606.5
Leukemialymphoblastic(MOLT-4)5.6
Liver19.15
Lung10
Lymphnode6.6
Lymphoma_burkitts(Daudi)10.05
Lymphoma_burkitts(Raji)12.05
MedullaOblongata62.3
OccipitalLobe204.25
OlfactoryBulb6.65
Ovary5
Pancreas10.5
PancreaticIslet12.9
ParietalLobe134.15
Pituitary9.35
Placenta6.55
Pons52.65
PrefrontalCortex574.2
Prostate13.3
Salivarygland6.85
SkeletalMuscle26.05
Skin5.85
SmoothMuscle8
Spinalcord37.4
SubthalamicNucleus113.1
SuperiorCervicalGanglion12.1
TemporalLobe157.05
Testis6.35
TestisGermCell6.1
TestisIntersitial6.15
TestisLeydigCell7.3
TestisSeminiferousTubule6.3
Thalamus58.75
Thymus5.45
Thyroid9.85
Tongue8.55
Tonsil7
Trachea6.2
TrigeminalGanglion14.95
Uterus8.35
UterusCorpus7.75
WholeBlood7.9
Wholebrain287.8
colon10.3
pineal_day14.56
pineal_night11.12
retina11.325
small_intestine8.05
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_10253_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.78 ± 0.67
Basal Forebrain4.09 ± 0.72
Basal Part of Pons4.29 ± 0.49
Cerebellar Cortex5.84 ± 0.3
Cerebellar Nuclei4.2 ± 0.43
Claustrum5.11 ± 0.92
Epithalamus4.66 ± 0.86
Frontal Lobe5.17 ± 0.77
Globus Pallidus2.95 ± 0.83
Hypothalamus4.37 ± 0.44
Insula5.61 ± 0.29
Limbic Lobe5.97 ± 0.83
Mesencephalon4.8 ± 0.94
Myelencephalon4.93 ± 0.76
Occipital Lobe4.84 ± 0.62
Parietal Lobe5 ± 0.65
Pontine Tegmentum5.09 ± 0.87
Striatum2.96 ± 1.18
Subthalamus4.53 ± 0.33
Temporal Lobe5.7 ± 0.6
Thalamus4.28 ± 0.76
White Matter2.96 ± 0.47
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00136141 13 22 34 IIASVPLAASPAR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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