AutismKB 2.0

Annotation Detail for CBX7


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Basic Information Top
Gene Symbol:CBX7 ( - )
Gene Full Name: chromobox homolog 7
Band: 22q13.1
Quick LinksEntrez ID:23492; OMIM: 608457; Uniprot ID:CBX7_HUMAN; ENSEMBL ID: ENSG00000100307; HGNC ID: 1557
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst2 / 6231932
fetus14 / 56401224
neonate0 / 310970 
infant1 / 2362042
juvenile8 / 55556143
adult103 / 193912153
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma5 / 8282360
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor5 / 11936941
germ cell tumor0 / 2638450 
glioma2 / 10688318
head and neck tumor2 / 13630214
kidney tumor1 / 6895914
leukemia3 / 9584231
liver tumor1 / 9635910
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia10 / 97250102
normal136 / 336030740
ovarian tumor1 / 7668213
pancreatic tumor16 / 104616152
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor3 / 12494924
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites0 / 400150 
bladder1 / 2975733
blood4 / 12347832
bone3 / 7165541
bone marrow0 / 488010 
brain51 / 110098946
cervix0 / 481710 
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye29 / 211054137
heart4 / 8962644
intestine6 / 23447225
kidney3 / 21177714
larynx2 / 2414582
liver3 / 20774314
lung16 / 33697447
lymph0 / 442700 
lymph node4 / 9161043
mammary gland1 / 1532716
mouth0 / 670520 
muscle1 / 1077159
nerve6 / 15768380
ovary2 / 10205119
pancreas21 / 21481297
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta1 / 2808253
prostate7 / 18934536
salivary gland0 / 201550 
skin10 / 21057447
spleen1 / 5395218
stomach5 / 9661951
testis0 / 3304420 
thymus1 / 8113112
thyroid1 / 4747321
tonsil1 / 1699958
trachea0 / 524130 
umbilical cord0 / 136800 
uterus3 / 23287812
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 212914_at
Cell line Expression level Expression bar
721_B_lymphoblasts27.4
Adipocyte21.6
AdrenalCortex57.2
Adrenalgland76.85
Amygdala377.35
Appendix85.9
AtrioventricularNode20.4
BDCA4+_DentriticCells66.7
Bonemarrow50.6
BronchialEpithelialCells14.95
CD105+_Endothelial22.1
CD14+_Monocytes23.25
CD19+_BCells(neg._sel.)255.85
CD33+_Myeloid28.05
CD34+27.8
CD4+_Tcells329.05
CD56+_NKCells113.35
CD71+_EarlyErythroid272.95
CD8+_Tcells353.6
CardiacMyocytes27.5
Caudatenucleus167.4
Cerebellum217.95
CerebellumPeduncles463.6
CiliaryGanglion27.5
CingulateCortex183.1
Colorectaladenocarcinoma62.45
DorsalRootGanglion55.1
FetalThyroid54
Fetalbrain23.55
Fetalliver23.6
Fetallung40.1
GlobusPallidus144.1
Heart200.35
Hypothalamus439.25
Kidney75.45
Leukemia_chronicMyelogenousK-56213
Leukemia_promyelocytic-HL-6019.15
Leukemialymphoblastic(MOLT-4)16
Liver63.6
Lung217.55
Lymphnode123.9
Lymphoma_burkitts(Daudi)15.6
Lymphoma_burkitts(Raji)61.85
MedullaOblongata227.45
OccipitalLobe212.6
OlfactoryBulb187.15
Ovary50.95
Pancreas47.15
PancreaticIslet115.15
ParietalLobe173.3
Pituitary114.5
Placenta74.8
Pons152.8
PrefrontalCortex784.15
Prostate342.3
Salivarygland62.5
SkeletalMuscle68.65
Skin18.4
SmoothMuscle7.6
Spinalcord102.35
SubthalamicNucleus237.3
SuperiorCervicalGanglion56.95
TemporalLobe228
Testis39.1
TestisGermCell42.1
TestisIntersitial43.35
TestisLeydigCell46.35
TestisSeminiferousTubule59.35
Thalamus187.9
Thymus71.55
Thyroid245.6
Tongue77.25
Tonsil73.45
Trachea58.65
TrigeminalGanglion44.15
Uterus302.9
UterusCorpus77.05
WholeBlood109.95
Wholebrain781
colon90.4
pineal_day425.9
pineal_night285.66
retina322.725
small_intestine86.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P250735
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala10.63 ± 0.38
Basal Forebrain10.79 ± 0.24
Basal Part of Pons11.04 ± 0.23
Cerebellar Cortex11.03 ± 0.18
Cerebellar Nuclei10.82 ± 0.39
Claustrum10.46 ± 0.44
Epithalamus10.53 ± 0.33
Frontal Lobe10.82 ± 0.26
Globus Pallidus10.17 ± 0.16
Hypothalamus10.57 ± 0.32
Insula10.91 ± 0.23
Limbic Lobe10.64 ± 0.33
Mesencephalon10.65 ± 0.29
Myelencephalon10.74 ± 0.37
Occipital Lobe10.67 ± 0.38
Parietal Lobe10.94 ± 0.31
Pontine Tegmentum10.69 ± 0.22
Striatum10.47 ± 0.34
Subthalamus10.92 ± 0.13
Temporal Lobe10.89 ± 0.24
Thalamus10.7 ± 0.24
White Matter10.23 ± 0.41
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Cbx7CBCerebellum3.56
6.17
Cbx7CTXCerebral cortex30.04
23.66
Cbx7HIPHippocampal region31.54
45.18
Cbx7HPFHippocampal formation25.82
32.54
Cbx7HYHypothalamus34.09
28.41
Cbx7LSXLateral septal complex0.48
0.92
Cbx7MBMidbrain14.57
14.8
Cbx7MYMedulla0.21
0.54
Cbx7OLFOlfactory bulb17.14
14.3
Cbx7PPons4.2
6.23
Cbx7PALPallidum31.2
29.98
Cbx7RHPRetrohippocampal region14.82
13.65
Cbx7sAMYStriatum-like amygdalar nuclei33.65
24.41
Cbx7STRStriatum28.64
22.3
Cbx7STRdStriatum dorsal region29.66
23.11
Cbx7STRvStriatum ventral region27.97
22.42
Cbx7THThalamus23.45
20.87
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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