AutismKB 2.0

Annotation Detail for ZFYVE26


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:ZFYVE26 ( DKFZp686F19106,DKFZp781H1112,KIAA0321,SPG15 )
Gene Full Name: zinc finger, FYVE domain containing 26
Band: 14q24.1
Quick LinksEntrez ID:23503; OMIM: 612012; Uniprot ID:ZFY26_HUMAN; ENSEMBL ID: ENSG00000072121; HGNC ID: 20761
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus30 / 56401253
neonate2 / 3109764
infant0 / 236200 
juvenile0 / 555560 
adult65 / 193912133
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor1 / 3436629
chondrosarcoma5 / 8282360
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor13 / 26384549
glioma2 / 10688318
head and neck tumor5 / 13630236
kidney tumor2 / 6895929
leukemia3 / 9584231
liver tumor2 / 9635920
lung tumor3 / 10312729
lymphoma5 / 7175569
non-neoplasia2 / 9725020
normal98 / 336030729
ovarian tumor1 / 7668213
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor3 / 12494924
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood3 / 12347824
bone2 / 7165527
bone marrow0 / 488010 
brain25 / 110098922
cervix1 / 4817120
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye5 / 21105423
heart1 / 8962611
intestine3 / 23447212
kidney9 / 21177742
larynx2 / 2414582
liver3 / 20774314
lung10 / 33697429
lymph4 / 4427090
lymph node5 / 9161054
mammary gland6 / 15327139
mouth3 / 6705244
muscle3 / 10771527
nerve0 / 157680 
ovary3 / 10205129
pancreas6 / 21481227
parathyroid1 / 2053948
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta11 / 28082539
prostate3 / 18934515
salivary gland0 / 201550 
skin5 / 21057423
spleen0 / 539520 
stomach0 / 966190 
testis4 / 33044212
thymus0 / 811310 
thyroid3 / 4747363
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord2 / 13680146
uterus7 / 23287830
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 37943_at
Cell line Expression level Expression bar
721_B_lymphoblasts15.25
Adipocyte16.9
AdrenalCortex27.2
Adrenalgland18.4
Amygdala16.5
Appendix28.2
AtrioventricularNode30.35
BDCA4+_DentriticCells42.75
Bonemarrow19.85
BronchialEpithelialCells14.4
CD105+_Endothelial15.2
CD14+_Monocytes19.55
CD19+_BCells(neg._sel.)16.4
CD33+_Myeloid26.25
CD34+20.65
CD4+_Tcells21.5
CD56+_NKCells18.55
CD71+_EarlyErythroid15.3
CD8+_Tcells26.35
CardiacMyocytes33.4
Caudatenucleus15
Cerebellum17.85
CerebellumPeduncles24.75
CiliaryGanglion21.65
CingulateCortex18.65
Colorectaladenocarcinoma20.4
DorsalRootGanglion20.4
FetalThyroid26.9
Fetalbrain19
Fetalliver14.35
Fetallung13.55
GlobusPallidus22.1
Heart27.1
Hypothalamus19.7
Kidney17.45
Leukemia_chronicMyelogenousK-56213.75
Leukemia_promyelocytic-HL-6016.05
Leukemialymphoblastic(MOLT-4)13.65
Liver25.35
Lung22.2
Lymphnode18.2
Lymphoma_burkitts(Daudi)25.6
Lymphoma_burkitts(Raji)32.5
MedullaOblongata15.4
OccipitalLobe16.5
OlfactoryBulb15.8
Ovary17.35
Pancreas16.6
PancreaticIslet19.05
ParietalLobe22.75
Pituitary24.85
Placenta19
Pons20.05
PrefrontalCortex26.4
Prostate20.85
Salivarygland14.85
SkeletalMuscle39.2
Skin27.95
SmoothMuscle19.2
Spinalcord23.7
SubthalamicNucleus19.85
SuperiorCervicalGanglion48.9
TemporalLobe19.25
Testis13.75
TestisGermCell13.35
TestisIntersitial15.9
TestisLeydigCell19.05
TestisSeminiferousTubule14.4
Thalamus18.15
Thymus18.85
Thyroid22.55
Tongue25.2
Tonsil22
Trachea13.4
TrigeminalGanglion41.4
Uterus18.1
UterusCorpus19.25
WholeBlood17.85
Wholebrain14.65
colon16.95
pineal_day22.46
pineal_night28.84
retina24
small_intestine17.4
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P32118
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.76 ± 0.33
Basal Forebrain7 ± 0.18
Basal Part of Pons6.54 ± 0.23
Cerebellar Cortex7.14 ± 0.35
Cerebellar Nuclei6.82 ± 0.19
Claustrum6.66 ± 0.45
Epithalamus7.24 ± 0.16
Frontal Lobe6.76 ± 0.25
Globus Pallidus7.03 ± 0.34
Hypothalamus6.67 ± 0.21
Insula6.77 ± 0.24
Limbic Lobe6.83 ± 0.3
Mesencephalon6.88 ± 0.39
Myelencephalon6.89 ± 0.34
Occipital Lobe7.25 ± 0.39
Parietal Lobe6.81 ± 0.25
Pontine Tegmentum6.94 ± 0.27
Striatum6.97 ± 0.34
Subthalamus6.74 ± 0.04
Temporal Lobe6.79 ± 0.25
Thalamus6.95 ± 0.2
White Matter7.71 ± 0.2
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Zfyve26HYHypothalamus1.42
1.42
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved