AutismKB 2.0

Annotation Detail for SUZ12


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Basic Information Top
Gene Symbol:SUZ12 ( CHET9,JJAZ1,KIAA0160 )
Gene Full Name: suppressor of zeste 12 homolog (Drosophila)
Band: 17q11.2
Quick LinksEntrez ID:23512; OMIM: 606245; Uniprot ID:SUZ12_HUMAN; ENSEMBL ID: ENSG00000178691; HGNC ID: 17101
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst2 / 6231932
fetus26 / 56401246
neonate2 / 3109764
infant0 / 236200 
juvenile1 / 5555617
adult84 / 193912143
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma2 / 17475114
breast (mammary gland) tumor1 / 9417810
cervical tumor4 / 34366116
chondrosarcoma1 / 8282312
colorectal tumor5 / 11424643
esophageal tumor0 / 172900 
gastrointestinal tumor6 / 11936950
germ cell tumor9 / 26384534
glioma1 / 1068839
head and neck tumor4 / 13630229
kidney tumor1 / 6895914
leukemia5 / 9584252
liver tumor4 / 9635941
lung tumor3 / 10312729
lymphoma2 / 7175527
non-neoplasia3 / 9725030
normal155 / 336030746
ovarian tumor5 / 7668265
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer5 / 10268048
retinoblastoma3 / 4635664
skin tumor6 / 12494948
soft tissue/muscle tissue tumor7 / 12519155
uterine tumor8 / 9025788
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites3 / 4001574
bladder3 / 29757100
blood5 / 12347840
bone3 / 7165541
bone marrow10 / 48801204
brain20 / 110098918
cervix4 / 4817183
connective tissue3 / 14925520
ear4 / 16212246
embryonic tissue8 / 21572237
esophagus0 / 202090 
eye24 / 211054113
heart4 / 8962644
intestine9 / 23447238
kidney5 / 21177723
larynx0 / 241450 
liver6 / 20774328
lung16 / 33697447
lymph2 / 4427045
lymph node18 / 91610196
mammary gland5 / 15327132
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary6 / 10205158
pancreas17 / 21481279
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta23 / 28082581
prostate7 / 18934536
salivary gland0 / 201550 
skin7 / 21057433
spleen0 / 539520 
stomach4 / 9661941
testis13 / 33044239
thymus3 / 8113136
thyroid4 / 4747384
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord2 / 13680146
uterus16 / 23287868
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 213971_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts121.25
Adipocyte21.2
AdrenalCortex31.1
Adrenalgland17.3
Amygdala124.7
Appendix32.7
AtrioventricularNode34.95
BDCA4+_DentriticCells137.5
Bonemarrow23
BronchialEpithelialCells19.2
CD105+_Endothelial39
CD14+_Monocytes31.9
CD19+_BCells(neg._sel.)83.2
CD33+_Myeloid33.7
CD34+113.25
CD4+_Tcells90
CD56+_NKCells38.3
CD71+_EarlyErythroid50.75
CD8+_Tcells63.6
CardiacMyocytes30.35
Caudatenucleus23.4
Cerebellum38.05
CerebellumPeduncles31.95
CiliaryGanglion20.2
CingulateCortex44.45
Colorectaladenocarcinoma112.2
DorsalRootGanglion33.6
FetalThyroid32.35
Fetalbrain55.1
Fetalliver23.5
Fetallung23.7
GlobusPallidus27.15
Heart29.7
Hypothalamus29.8
Kidney18.85
Leukemia_chronicMyelogenousK-56228.6
Leukemia_promyelocytic-HL-6046.85
Leukemialymphoblastic(MOLT-4)70.65
Liver26.35
Lung27
Lymphnode24.05
Lymphoma_burkitts(Daudi)53.35
Lymphoma_burkitts(Raji)44.25
MedullaOblongata42.35
OccipitalLobe40.85
OlfactoryBulb19.35
Ovary27.9
Pancreas24.2
PancreaticIslet26.7
ParietalLobe29.1
Pituitary49.55
Placenta22.9
Pons29.75
PrefrontalCortex56.6
Prostate39.2
Salivarygland21.95
SkeletalMuscle30.8
Skin25.2
SmoothMuscle23.85
Spinalcord23.2
SubthalamicNucleus24
SuperiorCervicalGanglion33.1
TemporalLobe53.3
Testis22.55
TestisGermCell56.65
TestisIntersitial42.35
TestisLeydigCell40.75
TestisSeminiferousTubule26.4
Thalamus24.15
Thymus78.25
Thyroid56.1
Tongue27.05
Tonsil37.3
Trachea22.3
TrigeminalGanglion47.95
Uterus49.5
UterusCorpus23.65
WholeBlood39.7
Wholebrain158.1
colon34.45
pineal_day91.72
pineal_night96.68
retina30.275
small_intestine27.8
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_32_P4324
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.41 ± 0.98
Basal Forebrain1.99 ± 0.27
Basal Part of Pons1.71 ± 0.53
Cerebellar Cortex2 ± 0.86
Cerebellar Nuclei2.34 ± 0.73
Claustrum2.94 ± 0.87
Epithalamus1.89 ± 0.61
Frontal Lobe1.89 ± 0.72
Globus Pallidus2.43 ± 0.24
Hypothalamus1.96 ± 0.66
Insula1.76 ± 0.52
Limbic Lobe1.95 ± 0.71
Mesencephalon2.13 ± 0.69
Myelencephalon2.02 ± 0.63
Occipital Lobe2.1 ± 0.67
Parietal Lobe2.03 ± 0.73
Pontine Tegmentum1.99 ± 0.68
Striatum2.08 ± 0.54
Subthalamus2.22 ± 0.78
Temporal Lobe1.91 ± 0.59
Thalamus2 ± 0.57
White Matter2.75 ± 0.78
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Suz12CBCerebellum64.45
74.37
Suz12CTXCerebral cortex54.94
38.49
Suz12HIPHippocampal region53.87
79.75
Suz12HPFHippocampal formation48.54
57.3
Suz12HYHypothalamus15.24
11.44
Suz12LSXLateral septal complex18.06
13.71
Suz12MBMidbrain28.85
24.67
Suz12MYMedulla24.42
22.83
Suz12OLFOlfactory bulb42.11
36.33
Suz12PPons20.84
19.19
Suz12PALPallidum17.05
14.44
Suz12RHPRetrohippocampal region40.12
29.05
Suz12sAMYStriatum-like amygdalar nuclei20.97
14.81
Suz12STRStriatum29.97
22.18
Suz12STRdStriatum dorsal region31.87
23.85
Suz12STRvStriatum ventral region30.27
20.83
Suz12THThalamus36.81
30.57
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00007126 35 41 75 SGGGSCGGGGSYSASSSSSAAAAAGAAVLPVKKPK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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