Annotation Detail for SCRIB
Basic Information Top
| Gene Symbol: | SCRIB ( CRIB1,SCRB1,SCRIB1,Vartul ) |
|---|---|
| Gene Full Name: | scribbled homolog (Drosophila) |
| Band: | 8q24.3 |
| Quick Links | Entrez ID:23513; OMIM: 607733; Uniprot ID:SCRIB_HUMAN; ENSEMBL ID: ENSG00000180900; HGNC ID: 30377 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.436329
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 6 / 70761 | 84 |  |
| blastocyst | 13 / 62319 | 208 |  |
| fetus | 7 / 564012 | 12 |  |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 1 / 55556 | 17 | |
| adult | 47 / 1939121 | 24 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 7 / 94178 | 74 | |
| cervical tumor | 1 / 34366 | 29 | |
| chondrosarcoma | 1 / 82823 | 12 | |
| colorectal tumor | 11 / 114246 | 96 | |
| esophageal tumor | 1 / 17290 | 57 | |
| gastrointestinal tumor | 4 / 119369 | 33 | |
| germ cell tumor | 20 / 263845 | 75 | |
| glioma | 10 / 106883 | 93 | |
| head and neck tumor | 0 / 136302 | 0 | |
| kidney tumor | 4 / 68959 | 58 | |
| leukemia | 3 / 95842 | 31 | |
| liver tumor | 1 / 96359 | 10 |  |
| lung tumor | 15 / 103127 | 145 | |
| lymphoma | 12 / 71755 | 167 | |
| non-neoplasia | 1 / 97250 | 10 | |
| normal | 61 / 3360307 | 18 | |
| ovarian tumor | 2 / 76682 | 26 | |
| pancreatic tumor | 7 / 104616 | 66 | |
| primitive neuroectodermal tumor of the CNS | 20 / 125680 | 159 | |
| prostate cancer | 4 / 102680 | 38 | |
| retinoblastoma | 14 / 46356 | 302 | |
| skin tumor | 27 / 124949 | 216 | |
| soft tissue/muscle tissue tumor | 9 / 125191 | 71 | |
| uterine tumor | 9 / 90257 | 99 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 2 / 33197 | 60 | |
| ascites | 1 / 40015 | 24 | |
| bladder | 0 / 29757 | 0 | |
| blood | 1 / 123478 | 8 | |
| bone | 1 / 71655 | 13 | |
| bone marrow | 1 / 48801 | 20 | |
| brain | 33 / 1100989 | 29 | |
| cervix | 4 / 48171 | 83 | |
| connective tissue | 0 / 149255 | 0 | |
| ear | 1 / 16212 | 61 | |
| embryonic tissue | 23 / 215722 | 106 | |
| esophagus | 1 / 20209 | 49 | |
| eye | 20 / 211054 | 94 | |
| heart | 0 / 89626 | 0 | |
| intestine | 18 / 234472 | 76 | |
| kidney | 5 / 211777 | 23 | |
| larynx | 0 / 24145 | 0 | |
| liver | 2 / 207743 | 9 | |
| lung | 21 / 336974 | 62 | |
| lymph | 12 / 44270 | 271 | |
| lymph node | 1 / 91610 | 10 | |
| mammary gland | 8 / 153271 | 52 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 5 / 107715 | 46 | |
| nerve | 2 / 15768 | 126 | |
| ovary | 10 / 102051 | 97 | |
| pancreas | 8 / 214812 | 37 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 4 / 280825 | 14 | |
| prostate | 5 / 189345 | 26 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 30 / 210574 | 142 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 1 / 96619 | 10 | |
| testis | 1 / 330442 | 3 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 17 / 232878 | 72 | |
| vascular | 0 / 51780 | 0 |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 212556_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 12.75 | |
| Adipocyte | 4.65 | |
| AdrenalCortex | 5.55 | |
| Adrenalgland | 4.45 | |
| Amygdala | 13.2 | |
| Appendix | 4.85 | |
| AtrioventricularNode | 4.2 | |
| BDCA4+_DentriticCells | 7.4 | |
| Bonemarrow | 5.1 | |
| BronchialEpithelialCells | 5.8 | |
| CD105+_Endothelial | 5.6 | |
| CD14+_Monocytes | 5.9 | |
| CD19+_BCells(neg._sel.) | 5.95 | |
| CD33+_Myeloid | 7.05 | |
| CD34+ | 13.95 | |
| CD4+_Tcells | 6.1 | |
| CD56+_NKCells | 9.05 | |
| CD71+_EarlyErythroid | 5 | |
| CD8+_Tcells | 5.8 | |
| CardiacMyocytes | 7.1 | |
| Caudatenucleus | 4.45 | |
| Cerebellum | 4.2 | |
| CerebellumPeduncles | 6.2 | |
| CiliaryGanglion | 3.8 | |
| CingulateCortex | 5.6 | |
| Colorectaladenocarcinoma | 9.9 | |
| DorsalRootGanglion | 4 | |
| FetalThyroid | 5.35 | |
| Fetalbrain | 7.95 | |
| Fetalliver | 3.6 | |
| Fetallung | 4.4 | |
| GlobusPallidus | 4.05 | |
| Heart | 33.65 | |
| Hypothalamus | 15.35 | |
| Kidney | 4.35 | |
| Leukemia_chronicMyelogenousK-562 | 7.55 | |
| Leukemia_promyelocytic-HL-60 | 4.85 | |
| Leukemialymphoblastic(MOLT-4) | 8.1 | |
| Liver | 7.2 | |
| Lung | 23.65 | |
| Lymphnode | 4.6 | |
| Lymphoma_burkitts(Daudi) | 6.95 | |
| Lymphoma_burkitts(Raji) | 16.8 | |
| MedullaOblongata | 4.95 | |
| OccipitalLobe | 4.95 | |
| OlfactoryBulb | 9.05 | |
| Ovary | 3.6 | |
| Pancreas | 9.3 | |
| PancreaticIslet | 5.75 | |
| ParietalLobe | 5.65 | |
| Pituitary | 5.35 | |
| Placenta | 10.25 | |
| Pons | 4.85 | |
| PrefrontalCortex | 6.95 | |
| Prostate | 11.6 | |
| Salivarygland | 3.8 | |
| SkeletalMuscle | 6.25 | |
| Skin | 3.7 | |
| SmoothMuscle | 6.2 | |
| Spinalcord | 5.9 | |
| SubthalamicNucleus | 4.55 | |
| SuperiorCervicalGanglion | 6.1 | |
| TemporalLobe | 5 | |
| Testis | 9.35 | |
| TestisGermCell | 4.45 | |
| TestisIntersitial | 4.45 | |
| TestisLeydigCell | 5 | |
| TestisSeminiferousTubule | 4.55 | |
| Thalamus | 6.3 | |
| Thymus | 6.3 | |
| Thyroid | 10.1 | |
| Tongue | 6.9 | |
| Tonsil | 5.25 | |
| Trachea | 3.9 | |
| TrigeminalGanglion | 5.3 | |
| Uterus | 5 | |
| UterusCorpus | 4.85 | |
| WholeBlood | 4.75 | |
| Wholebrain | 7.7 | |
| colon | 9.95 | |
| pineal_day | 7.98 | |
| pineal_night | 6.7 | |
| retina | 6.75 | |
| small_intestine | 8.5 | |
- Probe name: CUST_9070_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 4.23 ± 0.35 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 4.37 ± 0.41 | |
| Basal Part of Pons | 4.25 ± 0.46 | |
| Cerebellar Cortex | 4.52 ± 0.64 | |
| Cerebellar Nuclei | 4.2 ± 0.69 | |
| Claustrum | 3.71 ± 0.7 | |
| Epithalamus | 4.93 ± 0.69 | |
| Frontal Lobe | 4.28 ± 0.63 | |
| Globus Pallidus | 4.68 ± 0.28 | |
| Hypothalamus | 4.06 ± 0.73 | |
| Insula | 4.41 ± 0.42 | |
| Limbic Lobe | 4.19 ± 0.6 | |
| Mesencephalon | 4.35 ± 0.63 | |
| Myelencephalon | 4.38 ± 0.55 | |
| Occipital Lobe | 4.41 ± 0.5 | |
| Parietal Lobe | 4.29 ± 0.51 | |
| Pontine Tegmentum | 4.23 ± 0.61 | |
| Striatum | 4.01 ± 0.49 | |
| Subthalamus | 4 ± 0.16 | |
| Temporal Lobe | 4.45 ± 0.51 | |
| Thalamus | 4.55 ± 0.48 | |
| White Matter | 4.83 ± 0.17 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Scrib | CB | Cerebellum | 7.17 | |
| 7.19 | | |||
| Scrib | CTX | Cerebral cortex | 7.89 | |
| 5.15 | | |||
| Scrib | HIP | Hippocampal region | 7.25 | |
| 5.82 | | |||
| Scrib | HPF | Hippocampal formation | 7.52 | |
| 5.62 | | |||
| Scrib | HY | Hypothalamus | 9.89 | |
| 6.55 | | |||
| Scrib | LSX | Lateral septal complex | 1.17 | |
| 0.83 | | |||
| Scrib | MB | Midbrain | 8.75 | |
| 6.57 | | |||
| Scrib | MY | Medulla | 14.98 | |
| 13.34 | | |||
| Scrib | OLF | Olfactory bulb | 11.06 | |
| 7.92 | | |||
| Scrib | P | Pons | 12.33 | |
| 10.23 | | |||
| Scrib | PAL | Pallidum | 10.59 | |
| 7.6 | | |||
| Scrib | RHP | Retrohippocampal region | 8.07 | |
| 5.4 | | |||
| Scrib | sAMY | Striatum-like amygdalar nuclei | 7.53 | |
| 4.95 | | |||
| Scrib | STR | Striatum | 4.21 | |
| 3.28 | | |||
| Scrib | STRd | Striatum dorsal region | 3.35 | |
| 2.76 | | |||
| Scrib | STRv | Striatum ventral region | 7.28 | |
| 5.46 | | |||
| Scrib | TH | Thalamus | 8.99 | |
| 6.02 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00003258 | 21 | 928 | 948 | HDHAVSLLTAASPTIALLLER | Peptide Atlas |