AutismKB 2.0

Annotation Detail for MORC3


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Basic Information Top
Gene Symbol:MORC3 ( NXP2,ZCW5,ZCWCC3 )
Gene Full Name: MORC family CW-type zinc finger 3
Band: 21q22.12
Quick LinksEntrez ID:23515; OMIM: 610078; Uniprot ID:MORC3_HUMAN; ENSEMBL ID: ENSG00000159256; HGNC ID: 23572
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst0 / 623190 
fetus15 / 56401226
neonate2 / 3109764
infant0 / 236200 
juvenile0 / 555560 
adult80 / 193912141
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor7 / 9417874
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor11 / 26384541
glioma0 / 1068830 
head and neck tumor5 / 13630236
kidney tumor2 / 6895929
leukemia3 / 9584231
liver tumor3 / 9635931
lung tumor0 / 1031270 
lymphoma1 / 7175513
non-neoplasia4 / 9725041
normal86 / 336030725
ovarian tumor0 / 766820 
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma3 / 4635664
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder2 / 2975767
blood6 / 12347848
bone0 / 716550 
bone marrow2 / 4880140
brain23 / 110098920
cervix0 / 481710 
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus0 / 202090 
eye5 / 21105423
heart1 / 8962611
intestine4 / 23447217
kidney4 / 21177718
larynx3 / 24145124
liver5 / 20774324
lung5 / 33697414
lymph0 / 442700 
lymph node5 / 9161054
mammary gland7 / 15327145
mouth1 / 6705214
muscle2 / 10771518
nerve0 / 157680 
ovary0 / 1020510 
pancreas6 / 21481227
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta10 / 28082535
prostate2 / 18934510
salivary gland0 / 201550 
skin0 / 2105740 
spleen2 / 5395237
stomach1 / 9661910
testis14 / 33044242
thymus3 / 8113136
thyroid1 / 4747321
tonsil0 / 169990 
trachea5 / 5241395
umbilical cord0 / 136800 
uterus8 / 23287834
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 213000_at
Cell line Expression level Expression bar
721_B_lymphoblasts10.75
Adipocyte9.3
AdrenalCortex11.8
Adrenalgland8.6
Amygdala18.75
Appendix13.2
AtrioventricularNode10.35
BDCA4+_DentriticCells18
Bonemarrow10.6
BronchialEpithelialCells11.7
CD105+_Endothelial75.6
CD14+_Monocytes28.1
CD19+_BCells(neg._sel.)86.8
CD33+_Myeloid71.2
CD34+20.45
CD4+_Tcells26.7
CD56+_NKCells69.55
CD71+_EarlyErythroid22.45
CD8+_Tcells40.85
CardiacMyocytes15.05
Caudatenucleus9
Cerebellum8.1
CerebellumPeduncles12.15
CiliaryGanglion10.35
CingulateCortex11.15
Colorectaladenocarcinoma10.1
DorsalRootGanglion9.65
FetalThyroid10.6
Fetalbrain11.2
Fetalliver17.4
Fetallung11
GlobusPallidus8.4
Heart15.95
Hypothalamus10.8
Kidney8.65
Leukemia_chronicMyelogenousK-56211.55
Leukemia_promyelocytic-HL-608.45
Leukemialymphoblastic(MOLT-4)7.1
Liver14.45
Lung10.5
Lymphnode19.85
Lymphoma_burkitts(Daudi)13.15
Lymphoma_burkitts(Raji)16.3
MedullaOblongata8.9
OccipitalLobe10.85
OlfactoryBulb12.15
Ovary8.35
Pancreas8.45
PancreaticIslet10.5
ParietalLobe12
Pituitary12.15
Placenta9.2
Pons10.3
PrefrontalCortex16.5
Prostate11.6
Salivarygland9.2
SkeletalMuscle17.85
Skin12.7
SmoothMuscle10.9
Spinalcord10.95
SubthalamicNucleus10.05
SuperiorCervicalGanglion16.65
TemporalLobe9.8
Testis8.25
TestisGermCell7.95
TestisIntersitial8.9
TestisLeydigCell12.3
TestisSeminiferousTubule9.05
Thalamus10.75
Thymus7.55
Thyroid12.8
Tongue10.8
Tonsil11.45
Trachea8.75
TrigeminalGanglion12.7
Uterus29.15
UterusCorpus11.45
WholeBlood102.55
Wholebrain7.35
colon9.85
pineal_day17.16
pineal_night15.64
retina12.575
small_intestine8.9
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_6851_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.61 ± 0.47
Basal Forebrain5.15 ± 0.39
Basal Part of Pons5.42 ± 0.36
Cerebellar Cortex5.65 ± 0.2
Cerebellar Nuclei4.87 ± 0.54
Claustrum5.22 ± 0.53
Epithalamus5.31 ± 0.37
Frontal Lobe5.14 ± 0.47
Globus Pallidus5.36 ± 0.45
Hypothalamus5.14 ± 0.31
Insula5.34 ± 0.52
Limbic Lobe5.34 ± 0.36
Mesencephalon5.12 ± 0.44
Myelencephalon5.16 ± 0.46
Occipital Lobe5.42 ± 0.38
Parietal Lobe5.23 ± 0.38
Pontine Tegmentum5.25 ± 0.45
Striatum4.89 ± 0.35
Subthalamus4.71 ± 0.35
Temporal Lobe5.23 ± 0.35
Thalamus5.13 ± 0.4
White Matter5.94 ± 0.1
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Morc3CBCerebellum22.56
17.26
Morc3CTXCerebral cortex22.48
11.03
Morc3HIPHippocampal region52.69
31.06
Morc3HPFHippocampal formation46.26
25.65
Morc3HYHypothalamus23.52
12
Morc3LSXLateral septal complex16.19
7.34
Morc3MBMidbrain19.03
11.25
Morc3MYMedulla24.46
17.06
Morc3OLFOlfactory bulb38.19
16.44
Morc3PPons21.7
14.72
Morc3PALPallidum13.82
8.18
Morc3RHPRetrohippocampal region35.79
18.32
Morc3sAMYStriatum-like amygdalar nuclei22.52
10.55
Morc3STRStriatum12.14
5.55
Morc3STRdStriatum dorsal region8.67
4.16
Morc3STRvStriatum ventral region16.65
6.52
Morc3THThalamus14.05
7.67
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00030832 20 445 464 NCEVPEEPEDEDLVHPTYEK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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