AutismKB 2.0

Annotation Detail for SKIV2L2


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Basic Information Top
Gene Symbol:SKIV2L2 ( Dob1,KIAA0052,MGC142069,Mtr4,fSAP118 )
Gene Full Name: superkiller viralicidic activity 2-like 2 (S. cerevisiae)
Band: 5q11.2
Quick LinksEntrez ID:23517; OMIM: NA; Uniprot ID:SK2L2_HUMAN; ENSEMBL ID: ENSG00000039123; HGNC ID: 18734
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst13 / 62319208
fetus55 / 56401297
neonate2 / 3109764
infant0 / 236200 
juvenile2 / 5555635
adult163 / 193912184
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma1 / 1747557
breast (mammary gland) tumor9 / 9417895
cervical tumor3 / 3436687
chondrosarcoma3 / 8282336
colorectal tumor4 / 11424635
esophageal tumor1 / 1729057
gastrointestinal tumor3 / 11936925
germ cell tumor16 / 26384560
glioma3 / 10688328
head and neck tumor14 / 136302102
kidney tumor2 / 6895929
leukemia7 / 9584273
liver tumor3 / 9635931
lung tumor2 / 10312719
lymphoma8 / 71755111
non-neoplasia12 / 97250123
normal294 / 336030787
ovarian tumor5 / 7668265
pancreatic tumor7 / 10461666
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer31 / 102680301
retinoblastoma2 / 4635643
skin tumor10 / 12494980
soft tissue/muscle tissue tumor20 / 125191159
uterine tumor6 / 9025766
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder5 / 29757168
blood7 / 12347856
bone5 / 7165569
bone marrow5 / 48801102
brain105 / 110098995
cervix3 / 4817162
connective tissue30 / 149255200
ear1 / 1621261
embryonic tissue25 / 215722115
esophagus2 / 2020998
eye9 / 21105442
heart4 / 8962644
intestine10 / 23447242
kidney12 / 21177756
larynx0 / 241450 
liver13 / 20774362
lung19 / 33697456
lymph3 / 4427067
lymph node15 / 91610163
mammary gland14 / 15327191
mouth13 / 67052193
muscle4 / 10771537
nerve1 / 1576863
ovary3 / 10205129
pancreas15 / 21481269
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta25 / 28082589
prostate39 / 189345205
salivary gland0 / 201550 
skin17 / 21057480
spleen5 / 5395292
stomach2 / 9661920
testis77 / 330442233
thymus13 / 81131160
thyroid4 / 4747384
tonsil0 / 169990 
trachea39 / 52413744
umbilical cord0 / 136800 
uterus30 / 232878128
vascular4 / 5178077
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 212896_at
Cell line Expression level Expression bar
721_B_lymphoblasts334.75
Adipocyte47.4
AdrenalCortex37.25
Adrenalgland33.7
Amygdala46
Appendix44.9
AtrioventricularNode47.55
BDCA4+_DentriticCells299.3
Bonemarrow30.15
BronchialEpithelialCells77.4
CD105+_Endothelial183.45
CD14+_Monocytes60.1
CD19+_BCells(neg._sel.)85.05
CD33+_Myeloid82.1
CD34+330.35
CD4+_Tcells154.9
CD56+_NKCells167.65
CD71+_EarlyErythroid84.55
CD8+_Tcells93.85
CardiacMyocytes55.75
Caudatenucleus36.75
Cerebellum31.55
CerebellumPeduncles48.9
CiliaryGanglion30.7
CingulateCortex48.7
Colorectaladenocarcinoma37.9
DorsalRootGanglion35.45
FetalThyroid44.25
Fetalbrain54.8
Fetalliver37.6
Fetallung39.35
GlobusPallidus32.55
Heart32.1
Hypothalamus60.9
Kidney28.05
Leukemia_chronicMyelogenousK-562175.3
Leukemia_promyelocytic-HL-60169.15
Leukemialymphoblastic(MOLT-4)45.6
Liver53.4
Lung20.9
Lymphnode39.85
Lymphoma_burkitts(Daudi)116.05
Lymphoma_burkitts(Raji)69.1
MedullaOblongata43.55
OccipitalLobe41.3
OlfactoryBulb35.3
Ovary30.05
Pancreas32.75
PancreaticIslet73.5
ParietalLobe45.8
Pituitary55.75
Placenta11
Pons41.95
PrefrontalCortex91.9
Prostate48.05
Salivarygland36.75
SkeletalMuscle45.85
Skin33.55
SmoothMuscle68.3
Spinalcord45.4
SubthalamicNucleus48.2
SuperiorCervicalGanglion47.9
TemporalLobe40.95
Testis29.8
TestisGermCell117.2
TestisIntersitial111.1
TestisLeydigCell81.65
TestisSeminiferousTubule57.5
Thalamus44.75
Thymus20.5
Thyroid53.1
Tongue41.45
Tonsil67.7
Trachea28.45
TrigeminalGanglion41.95
Uterus54
UterusCorpus39.95
WholeBlood48.4
Wholebrain23.8
colon42.25
pineal_day146.92
pineal_night112.26
retina49.625
small_intestine39.15
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_8556_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.52 ± 0.13
Basal Forebrain8.51 ± 0.17
Basal Part of Pons8.58 ± 0.12
Cerebellar Cortex8.53 ± 0.16
Cerebellar Nuclei8.64 ± 0.17
Claustrum8.63 ± 0.16
Epithalamus8.44 ± 0.11
Frontal Lobe8.51 ± 0.16
Globus Pallidus8.74 ± 0.1
Hypothalamus8.63 ± 0.1
Insula8.48 ± 0.14
Limbic Lobe8.54 ± 0.19
Mesencephalon8.52 ± 0.19
Myelencephalon8.49 ± 0.18
Occipital Lobe8.48 ± 0.2
Parietal Lobe8.54 ± 0.17
Pontine Tegmentum8.58 ± 0.17
Striatum8.44 ± 0.14
Subthalamus8.68 ± 0.07
Temporal Lobe8.55 ± 0.16
Thalamus8.47 ± 0.17
White Matter9.1 ± 0.29
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Skiv2l2CBCerebellum19.87
25.43
Skiv2l2CTXCerebral cortex59.71
41.4
Skiv2l2HIPHippocampal region36.77
51.88
Skiv2l2HPFHippocampal formation43.2
45.63
Skiv2l2HYHypothalamus19.03
14.32
Skiv2l2LSXLateral septal complex28.23
20.88
Skiv2l2MBMidbrain31.77
28.27
Skiv2l2MYMedulla42.91
48.37
Skiv2l2OLFOlfactory bulb45.82
35.64
Skiv2l2PPons34.43
35.73
Skiv2l2PALPallidum27.23
22.96
Skiv2l2RHPRetrohippocampal region51.56
38.94
Skiv2l2sAMYStriatum-like amygdalar nuclei17.91
10.57
Skiv2l2STRStriatum30.09
20.77
Skiv2l2STRdStriatum dorsal region28.62
18.99
Skiv2l2STRvStriatum ventral region44.61
32.47
Skiv2l2THThalamus32.32
25.52
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00001903 22 146 167 EAIQCVDNNQSVLVSAHTSAGK Peptide Atlas
SK2L2_HUMAN_0 1 0 0 AQIAIDIKSAKR PRIDE
SK2L2_HUMAN_482 17 482 498 ALFATETFAMGINMPAR PRIDE
SK2L2_HUMAN_761 13 761 773 QSVLKSIQEVQKR PRIDE
SK2L2_HUMAN_86 17 86 102 IEESITEDLSLADLMPR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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