AutismKB 2.0

Annotation Detail for MYST4


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Basic Information Top
Gene Symbol:MYST4 ( DKFZp313G1618,FLJ90335,KAT6B,KIAA0383,MORF,MOZ2,qkf,querkopf )
Gene Full Name: MYST histone acetyltransferase (monocytic leukemia) 4
Band: 10q22.2
Quick LinksEntrez ID:23522; OMIM: 605880; Uniprot ID:MYST4_HUMAN; ENSEMBL ID: ENSG00000156650; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst2 / 6231932
fetus34 / 56401260
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult96 / 193912149
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor6 / 9417863
cervical tumor0 / 343660 
chondrosarcoma3 / 8282336
colorectal tumor3 / 11424626
esophageal tumor2 / 17290115
gastrointestinal tumor4 / 11936933
germ cell tumor19 / 26384572
glioma3 / 10688328
head and neck tumor11 / 13630280
kidney tumor1 / 6895914
leukemia5 / 9584252
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma2 / 7175527
non-neoplasia4 / 9725041
normal153 / 336030745
ovarian tumor4 / 7668252
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS5 / 12568039
prostate cancer3 / 10268029
retinoblastoma1 / 4635621
skin tumor1 / 1249498
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites2 / 4001549
bladder0 / 297570 
blood2 / 12347816
bone2 / 7165527
bone marrow2 / 4880140
brain67 / 110098960
cervix0 / 481710 
connective tissue1 / 1492556
ear1 / 1621261
embryonic tissue9 / 21572241
esophagus2 / 2020998
eye4 / 21105418
heart1 / 8962611
intestine4 / 23447217
kidney12 / 21177756
larynx1 / 2414541
liver2 / 2077439
lung19 / 33697456
lymph1 / 4427022
lymph node6 / 9161065
mammary gland14 / 15327191
mouth2 / 6705229
muscle8 / 10771574
nerve0 / 157680 
ovary5 / 10205148
pancreas13 / 21481260
parathyroid1 / 2053948
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta6 / 28082521
prostate8 / 18934542
salivary gland0 / 201550 
skin5 / 21057423
spleen2 / 5395237
stomach2 / 9661920
testis9 / 33044227
thymus0 / 811310 
thyroid7 / 47473147
tonsil0 / 169990 
trachea4 / 5241376
umbilical cord0 / 136800 
uterus2 / 2328788
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 211874_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts9.15
Adipocyte5.7
AdrenalCortex6.3
Adrenalgland4.95
Amygdala5.55
Appendix6.1
AtrioventricularNode4.75
BDCA4+_DentriticCells6.25
Bonemarrow6
BronchialEpithelialCells5.45
CD105+_Endothelial5.45
CD14+_Monocytes6.45
CD19+_BCells(neg._sel.)6.55
CD33+_Myeloid7.25
CD34+7.6
CD4+_Tcells7.7
CD56+_NKCells7.25
CD71+_EarlyErythroid5.6
CD8+_Tcells9.05
CardiacMyocytes7.3
Caudatenucleus5.5
Cerebellum5
CerebellumPeduncles7.9
CiliaryGanglion4.25
CingulateCortex5.75
Colorectaladenocarcinoma5.75
DorsalRootGanglion4.7
FetalThyroid10.75
Fetalbrain11.55
Fetalliver5.15
Fetallung5.05
GlobusPallidus4.7
Heart9.55
Hypothalamus6.2
Kidney5.3
Leukemia_chronicMyelogenousK-5625.5
Leukemia_promyelocytic-HL-605.3
Leukemialymphoblastic(MOLT-4)5
Liver7.95
Lung15.1
Lymphnode6.45
Lymphoma_burkitts(Daudi)7.95
Lymphoma_burkitts(Raji)8.5
MedullaOblongata6.1
OccipitalLobe5.15
OlfactoryBulb4.8
Ovary4.15
Pancreas4.9
PancreaticIslet6.45
ParietalLobe7.25
Pituitary8
Placenta6
Pons6
PrefrontalCortex7.45
Prostate6.9
Salivarygland4.55
SkeletalMuscle8.4
Skin4.55
SmoothMuscle6.8
Spinalcord6.5
SubthalamicNucleus7.5
SuperiorCervicalGanglion6.85
TemporalLobe5.5
Testis5.2
TestisGermCell5.55
TestisIntersitial5.4
TestisLeydigCell9.45
TestisSeminiferousTubule5.2
Thalamus5.7
Thymus12.6
Thyroid7.35
Tongue7.5
Tonsil6.65
Trachea5.3
TrigeminalGanglion6.05
Uterus7.5
UterusCorpus6.65
WholeBlood7.7
Wholebrain5.15
colon6.05
pineal_day7.6
pineal_night7.06
retina6.75
small_intestine5.5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P941586
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.94 ± 0.55
Basal Forebrain6.29 ± 0.3
Basal Part of Pons5.66 ± 0.29
Cerebellar Cortex6.29 ± 0.24
Cerebellar Nuclei5.96 ± 0.32
Claustrum5.86 ± 0.56
Epithalamus6.44 ± 0.24
Frontal Lobe5.96 ± 0.34
Globus Pallidus6.54 ± 0.29
Hypothalamus6.04 ± 0.35
Insula6.05 ± 0.21
Limbic Lobe6.07 ± 0.33
Mesencephalon6.26 ± 0.45
Myelencephalon6.12 ± 0.41
Occipital Lobe6.45 ± 0.38
Parietal Lobe6.15 ± 0.34
Pontine Tegmentum6.1 ± 0.38
Striatum6.16 ± 0.39
Subthalamus6.06 ± 0.44
Temporal Lobe6 ± 0.37
Thalamus6.13 ± 0.32
White Matter6.53 ± 0.37
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Myst4CBCerebellum40.2
70.51
Myst4CTXCerebral cortex32.09
23.45
Myst4HIPHippocampal region21.61
26.04
Myst4HPFHippocampal formation19.07
20.37
Myst4HYHypothalamus20.17
17.4
Myst4LSXLateral septal complex22.14
18.92
Myst4MBMidbrain14.26
13.54
Myst4MYMedulla25.55
24.25
Myst4OLFOlfactory bulb50.51
49.18
Myst4PPons18.53
16.97
Myst4PALPallidum17.89
15.68
Myst4RHPRetrohippocampal region13.85
11.34
Myst4sAMYStriatum-like amygdalar nuclei16.89
14.55
Myst4STRStriatum22.97
19.12
Myst4STRdStriatum dorsal region18.54
14.68
Myst4STRvStriatum ventral region39.79
32.61
Myst4THThalamus17.31
14.6
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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