AutismKB 2.0

Annotation Detail for CABIN1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:CABIN1 ( CAIN,KIAA0330,PPP3IN )
Gene Full Name: calcineurin binding protein 1
Band: 22q11.23
Quick LinksEntrez ID:23523; OMIM: 604251; Uniprot ID:CABIN_HUMAN; ENSEMBL ID: ENSG00000099991; HGNC ID: 24187
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst8 / 62319128
fetus20 / 56401235
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult99 / 193912151
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor5 / 9417853
cervical tumor0 / 343660 
chondrosarcoma10 / 82823120
colorectal tumor11 / 11424696
esophageal tumor0 / 172900 
gastrointestinal tumor11 / 11936992
germ cell tumor12 / 26384545
glioma5 / 10688346
head and neck tumor5 / 13630236
kidney tumor5 / 6895972
leukemia8 / 9584283
liver tumor1 / 9635910
lung tumor10 / 10312796
lymphoma8 / 71755111
non-neoplasia2 / 9725020
normal141 / 336030741
ovarian tumor5 / 7668265
pancreatic tumor10 / 10461695
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer6 / 10268058
retinoblastoma3 / 4635664
skin tumor12 / 12494996
soft tissue/muscle tissue tumor7 / 12519155
uterine tumor8 / 9025788
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites3 / 4001574
bladder0 / 297570 
blood4 / 12347832
bone9 / 71655125
bone marrow3 / 4880161
brain26 / 110098923
cervix0 / 481710 
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue17 / 21572278
esophagus0 / 202090 
eye33 / 211054156
heart2 / 8962622
intestine23 / 23447298
kidney7 / 21177733
larynx0 / 241450 
liver7 / 20774333
lung16 / 33697447
lymph8 / 44270180
lymph node9 / 9161098
mammary gland5 / 15327132
mouth1 / 6705214
muscle3 / 10771527
nerve0 / 157680 
ovary7 / 10205168
pancreas11 / 21481251
parathyroid0 / 205390 
pharynx5 / 41328120
pituitary gland0 / 165850 
placenta4 / 28082514
prostate8 / 18934542
salivary gland0 / 201550 
skin14 / 21057466
spleen3 / 5395255
stomach8 / 9661982
testis10 / 33044230
thymus4 / 8113149
thyroid4 / 4747384
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus15 / 23287864
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202624_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts71.6
Adipocyte60.55
AdrenalCortex58.05
Adrenalgland35.7
Amygdala70.25
Appendix56.5
AtrioventricularNode47.7
BDCA4+_DentriticCells41.4
Bonemarrow54.5
BronchialEpithelialCells53.7
CD105+_Endothelial57.2
CD14+_Monocytes76.15
CD19+_BCells(neg._sel.)60.6
CD33+_Myeloid72.25
CD34+73.35
CD4+_Tcells101.3
CD56+_NKCells75.75
CD71+_EarlyErythroid52.45
CD8+_Tcells231.65
CardiacMyocytes69.3
Caudatenucleus51.35
Cerebellum70.95
CerebellumPeduncles102.7
CiliaryGanglion35.8
CingulateCortex97
Colorectaladenocarcinoma59.75
DorsalRootGanglion43.15
FetalThyroid99.3
Fetalbrain59.4
Fetalliver27.5
Fetallung51.15
GlobusPallidus39.1
Heart69.9
Hypothalamus58.2
Kidney40.85
Leukemia_chronicMyelogenousK-56256.1
Leukemia_promyelocytic-HL-6043.35
Leukemialymphoblastic(MOLT-4)75.45
Liver72.6
Lung112.15
Lymphnode56.85
Lymphoma_burkitts(Daudi)73.95
Lymphoma_burkitts(Raji)122.85
MedullaOblongata68
OccipitalLobe50.75
OlfactoryBulb44.55
Ovary37.15
Pancreas44.05
PancreaticIslet48.5
ParietalLobe61.1
Pituitary56.65
Placenta44.25
Pons72.15
PrefrontalCortex147.2
Prostate66.45
Salivarygland44.55
SkeletalMuscle61.7
Skin42.7
SmoothMuscle64
Spinalcord63.65
SubthalamicNucleus50.85
SuperiorCervicalGanglion68.45
TemporalLobe65.1
Testis47.2
TestisGermCell85.5
TestisIntersitial62.9
TestisLeydigCell56.15
TestisSeminiferousTubule72.35
Thalamus66.85
Thymus79.45
Thyroid116.7
Tongue52.85
Tonsil66.85
Trachea47.15
TrigeminalGanglion55.2
Uterus69.1
UterusCorpus53.65
WholeBlood176.15
Wholebrain59.95
colon56.6
pineal_day61.26
pineal_night58.72
retina69.8
small_intestine47.6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P102512
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala10.11 ± 0.29
Basal Forebrain9.94 ± 0.16
Basal Part of Pons10.01 ± 0.22
Cerebellar Cortex10.21 ± 0.25
Cerebellar Nuclei9.77 ± 0.2
Claustrum10.33 ± 0.38
Epithalamus10.4 ± 0.42
Frontal Lobe9.8 ± 0.33
Globus Pallidus9.97 ± 0.21
Hypothalamus9.62 ± 0.22
Insula9.81 ± 0.37
Limbic Lobe10.13 ± 0.34
Mesencephalon9.94 ± 0.32
Myelencephalon9.94 ± 0.36
Occipital Lobe10.29 ± 0.39
Parietal Lobe9.93 ± 0.37
Pontine Tegmentum9.82 ± 0.32
Striatum10.08 ± 0.35
Subthalamus9.58 ± 0.27
Temporal Lobe9.88 ± 0.29
Thalamus9.8 ± 0.24
White Matter10.42 ± 0.47
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Cabin1CBCerebellum22.53
23.09
Cabin1CTXCerebral cortex62.99
46.23
Cabin1HIPHippocampal region48.71
66.84
Cabin1HPFHippocampal formation57.18
61.82
Cabin1HYHypothalamus17.77
12.38
Cabin1LSXLateral septal complex29.87
19.68
Cabin1MBMidbrain22.78
17.84
Cabin1MYMedulla23.01
20.66
Cabin1OLFOlfactory bulb63.15
51.03
Cabin1PPons20.52
17.27
Cabin1PALPallidum20.82
16.1
Cabin1RHPRetrohippocampal region71.22
56.91
Cabin1sAMYStriatum-like amygdalar nuclei42.39
28.37
Cabin1STRStriatum19.83
13.73
Cabin1STRdStriatum dorsal region13.74
9.5
Cabin1STRvStriatum ventral region26.7
18.31
Cabin1THThalamus33.34
24.01
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00025639 8 1189 1196 HCFTSAAR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved