AutismKB 2.0

Annotation Detail for SRRM2


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Basic Information Top
Gene Symbol:SRRM2 ( 300-KD,CWF21,Cwc21,DKFZp667L0421,DKFZp686O15166,FLJ21926,FLJ22250,KIAA0324,MGC40295,SRL300,SRm300 )
Gene Full Name: serine/arginine repetitive matrix 2
Band: 16p13.3
Quick LinksEntrez ID:23524; OMIM: 606032; Uniprot ID:SRRM2_HUMAN; ENSEMBL ID: ENSG00000167978; HGNC ID: 16639
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body17 / 70761240
blastocyst24 / 62319385
fetus57 / 564012101
neonate3 / 3109796
infant1 / 2362042
juvenile6 / 55556107
adult914 / 1939121471
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma19 / 174751087
breast (mammary gland) tumor40 / 94178424
cervical tumor2 / 3436658
chondrosarcoma9 / 82823108
colorectal tumor113 / 114246989
esophageal tumor2 / 17290115
gastrointestinal tumor17 / 119369142
germ cell tumor63 / 263845238
glioma12 / 106883112
head and neck tumor73 / 136302535
kidney tumor12 / 68959174
leukemia51 / 95842532
liver tumor2 / 9635920
lung tumor98 / 103127950
lymphoma7 / 7175597
non-neoplasia31 / 97250318
normal622 / 3360307185
ovarian tumor13 / 76682169
pancreatic tumor13 / 104616124
primitive neuroectodermal tumor of the CNS11 / 12568087
prostate cancer47 / 102680457
retinoblastoma5 / 46356107
skin tumor7 / 12494956
soft tissue/muscle tissue tumor5 / 12519139
uterine tumor38 / 90257421
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland2 / 3319760
ascites2 / 4001549
bladder20 / 29757672
blood52 / 123478421
bone11 / 71655153
bone marrow2 / 4880140
brain205 / 1100989186
cervix2 / 4817141
connective tissue7 / 14925546
ear1 / 1621261
embryonic tissue57 / 215722264
esophagus2 / 2020998
eye24 / 211054113
heart8 / 8962689
intestine157 / 234472669
kidney50 / 211777236
larynx34 / 241451408
liver21 / 207743101
lung160 / 336974474
lymph6 / 44270135
lymph node34 / 91610371
mammary gland51 / 153271332
mouth11 / 67052164
muscle10 / 10771592
nerve8 / 15768507
ovary23 / 102051225
pancreas27 / 214812125
parathyroid0 / 205390 
pharynx8 / 41328193
pituitary gland0 / 165850 
placenta70 / 280825249
prostate97 / 189345512
salivary gland0 / 201550 
skin37 / 210574175
spleen9 / 53952166
stomach17 / 96619175
testis41 / 330442124
thymus17 / 81131209
thyroid37 / 47473779
tonsil1 / 1699958
trachea2 / 5241338
umbilical cord3 / 13680219
uterus59 / 232878253
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 207435_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts389.3
Adipocyte248.65
AdrenalCortex311.85
Adrenalgland190.7
Amygdala367.3
Appendix171
AtrioventricularNode168.45
BDCA4+_DentriticCells677.25
Bonemarrow279.9
BronchialEpithelialCells235.7
CD105+_Endothelial512.55
CD14+_Monocytes338.5
CD19+_BCells(neg._sel.)450.4
CD33+_Myeloid581.1
CD34+731.75
CD4+_Tcells824.1
CD56+_NKCells403.45
CD71+_EarlyErythroid418.05
CD8+_Tcells893.45
CardiacMyocytes324.75
Caudatenucleus237.95
Cerebellum302.8
CerebellumPeduncles273.9
CiliaryGanglion143.3
CingulateCortex237.5
Colorectaladenocarcinoma479.75
DorsalRootGanglion116.4
FetalThyroid405.45
Fetalbrain306.25
Fetalliver265
Fetallung364.4
GlobusPallidus148.15
Heart262.05
Hypothalamus346.4
Kidney166.5
Leukemia_chronicMyelogenousK-562387.25
Leukemia_promyelocytic-HL-60364.7
Leukemialymphoblastic(MOLT-4)330.7
Liver143.5
Lung528.45
Lymphnode548.7
Lymphoma_burkitts(Daudi)451.1
Lymphoma_burkitts(Raji)1454.85
MedullaOblongata230.95
OccipitalLobe257.35
OlfactoryBulb427.65
Ovary159.4
Pancreas264.1
PancreaticIslet372.95
ParietalLobe305.45
Pituitary402.95
Placenta279.4
Pons162.3
PrefrontalCortex443.1
Prostate522.4
Salivarygland252.45
SkeletalMuscle338.5
Skin168.15
SmoothMuscle207.05
Spinalcord380.7
SubthalamicNucleus129.8
SuperiorCervicalGanglion233.15
TemporalLobe147.6
Testis305.3
TestisGermCell334.05
TestisIntersitial222.1
TestisLeydigCell206.1
TestisSeminiferousTubule277.15
Thalamus299.35
Thymus344.8
Thyroid543.25
Tongue330.95
Tonsil277.4
Trachea393.7
TrigeminalGanglion108.85
Uterus429.4
UterusCorpus277.75
WholeBlood329.1
Wholebrain200.2
colon373.85
pineal_day795.48
pineal_night616.86
retina441.475
small_intestine353.05
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P323166
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala10.54 ± 0.27
Basal Forebrain10.76 ± 0.16
Basal Part of Pons11.09 ± 0.27
Cerebellar Cortex11.26 ± 0.25
Cerebellar Nuclei10.98 ± 0.25
Claustrum10.8 ± 0.32
Epithalamus10.95 ± 0.37
Frontal Lobe10.85 ± 0.36
Globus Pallidus10.8 ± 0.13
Hypothalamus10.65 ± 0.66
Insula11.02 ± 0.27
Limbic Lobe10.77 ± 0.39
Mesencephalon10.81 ± 0.37
Myelencephalon10.89 ± 0.45
Occipital Lobe11.11 ± 0.38
Parietal Lobe10.9 ± 0.3
Pontine Tegmentum10.83 ± 0.33
Striatum10.69 ± 0.34
Subthalamus11.04 ± 0.1
Temporal Lobe10.94 ± 0.36
Thalamus11.03 ± 0.3
White Matter11.96 ± 0.16
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00007213 20 1021 1040 SKDSLVQSCPGSLSLCAGVK Peptide Atlas
SRRM2_HUMAN_1 11 1 11 MYNGIGLPTPR PRIDE
SRRM2_HUMAN_1119 10 1119 1128 GEFSASPMLK PRIDE
SRRM2_HUMAN_1185 19 1185 1203 DKFSPFPVQDRPESSLVFK PRIDE
SRRM2_HUMAN_1324 11 1324 1334 ENSFGSPLEFR PRIDE
SRRM2_HUMAN_2032 8 2032 2039 SRTPLLPR PRIDE
SRRM2_HUMAN_2044 8 2044 2051 SRSPLAIR PRIDE
SRRM2_HUMAN_2067 10 2067 2076 SLTRSPPAIR PRIDE
SRRM2_HUMAN_2089 24 2089 2112 SATPPATRNHSGSRTPPVALNSSR PRIDE
SRRM2_HUMAN_2261 14 2261 2274 TPAAAAAMNLASPR PRIDE
SRRM2_HUMAN_2690 9 2690 2698 SLSYSPVER PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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