AutismKB 2.0

Annotation Detail for TNPO3


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Basic Information Top
Gene Symbol:TNPO3 ( IPO12,MTR10A,TRN-SR,TRN-SR2,TRNSR )
Gene Full Name: transportin 3
Band: 7q32.1
Quick LinksEntrez ID:23534; OMIM: 610032; Uniprot ID:TNPO3_HUMAN; ENSEMBL ID: ENSG00000064419; HGNC ID: 17103
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst13 / 62319208
fetus71 / 564012125
neonate4 / 31097128
infant1 / 2362042
juvenile4 / 5555671
adult155 / 193912179
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor14 / 94178148
cervical tumor5 / 34366145
chondrosarcoma5 / 8282360
colorectal tumor22 / 114246192
esophageal tumor1 / 1729057
gastrointestinal tumor12 / 119369100
germ cell tumor67 / 263845253
glioma4 / 10688337
head and neck tumor19 / 136302139
kidney tumor5 / 6895972
leukemia7 / 9584273
liver tumor5 / 9635951
lung tumor6 / 10312758
lymphoma3 / 7175541
non-neoplasia8 / 9725082
normal249 / 336030774
ovarian tumor6 / 7668278
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS8 / 12568063
prostate cancer1 / 1026809
retinoblastoma4 / 4635686
skin tumor5 / 12494940
soft tissue/muscle tissue tumor10 / 12519179
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites7 / 40015174
bladder3 / 29757100
blood8 / 12347864
bone2 / 7165527
bone marrow3 / 4880161
brain114 / 1100989103
cervix5 / 48171103
connective tissue12 / 14925580
ear0 / 162120 
embryonic tissue24 / 215722111
esophagus1 / 2020949
eye10 / 21105447
heart9 / 89626100
intestine33 / 234472140
kidney17 / 21177780
larynx0 / 241450 
liver7 / 20774333
lung25 / 33697474
lymph0 / 442700 
lymph node7 / 9161076
mammary gland16 / 153271104
mouth15 / 67052223
muscle5 / 10771546
nerve0 / 157680 
ovary4 / 10205139
pancreas7 / 21481232
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland1 / 1658560
placenta20 / 28082571
prostate4 / 18934521
salivary gland4 / 20155198
skin14 / 21057466
spleen0 / 539520 
stomach7 / 9661972
testis64 / 330442193
thymus9 / 81131110
thyroid2 / 4747342
tonsil0 / 169990 
trachea6 / 52413114
umbilical cord0 / 136800 
uterus16 / 23287868
vascular6 / 51780115
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 214550_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts155.95
Adipocyte13.35
AdrenalCortex14.95
Adrenalgland11.3
Amygdala14.05
Appendix13.55
AtrioventricularNode10.7
BDCA4+_DentriticCells48.35
Bonemarrow13.75
BronchialEpithelialCells19.4
CD105+_Endothelial21.05
CD14+_Monocytes18.25
CD19+_BCells(neg._sel.)22.55
CD33+_Myeloid23.3
CD34+41.3
CD4+_Tcells27.7
CD56+_NKCells83.25
CD71+_EarlyErythroid17.35
CD8+_Tcells22.85
CardiacMyocytes30.5
Caudatenucleus12.35
Cerebellum10.6
CerebellumPeduncles16
CiliaryGanglion10.1
CingulateCortex15.2
Colorectaladenocarcinoma19.1
DorsalRootGanglion10.8
FetalThyroid14.75
Fetalbrain14.05
Fetalliver11.7
Fetallung10.6
GlobusPallidus10.15
Heart17.7
Hypothalamus14.15
Kidney11.05
Leukemia_chronicMyelogenousK-56228.35
Leukemia_promyelocytic-HL-6016.3
Leukemialymphoblastic(MOLT-4)53.3
Liver19.15
Lung14.95
Lymphnode11.25
Lymphoma_burkitts(Daudi)18.1
Lymphoma_burkitts(Raji)19.3
MedullaOblongata11
OccipitalLobe12.15
OlfactoryBulb11.35
Ovary8.55
Pancreas11.8
PancreaticIslet17.85
ParietalLobe15.05
Pituitary15.25
Placenta13.95
Pons13.05
PrefrontalCortex29
Prostate16.05
Salivarygland10.6
SkeletalMuscle16.55
Skin10.85
SmoothMuscle61.3
Spinalcord13.95
SubthalamicNucleus12.9
SuperiorCervicalGanglion15.15
TemporalLobe12
Testis14.7
TestisGermCell35.5
TestisIntersitial28.9
TestisLeydigCell20.05
TestisSeminiferousTubule22.4
Thalamus13.75
Thymus15.6
Thyroid16.9
Tongue13.5
Tonsil14.4
Trachea11.3
TrigeminalGanglion14.4
Uterus10.55
UterusCorpus11.75
WholeBlood14.85
Wholebrain11.15
colon13.7
pineal_day38.6
pineal_night42.24
retina16.825
small_intestine14.6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_10849_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.79 ± 0.28
Basal Forebrain6.08 ± 0.38
Basal Part of Pons5.97 ± 0.35
Cerebellar Cortex6.29 ± 0.19
Cerebellar Nuclei5.85 ± 0.35
Claustrum5.82 ± 0.7
Epithalamus6.01 ± 0.48
Frontal Lobe5.97 ± 0.32
Globus Pallidus5.67 ± 0.19
Hypothalamus6.16 ± 0.42
Insula5.91 ± 0.24
Limbic Lobe5.92 ± 0.39
Mesencephalon5.94 ± 0.48
Myelencephalon5.91 ± 0.4
Occipital Lobe5.87 ± 0.33
Parietal Lobe5.88 ± 0.38
Pontine Tegmentum5.94 ± 0.4
Striatum5.46 ± 0.32
Subthalamus6.11 ± 0.09
Temporal Lobe5.98 ± 0.36
Thalamus5.96 ± 0.37
White Matter6.34 ± 0.21
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Tnpo3CBCerebellum20.06
20.42
Tnpo3CTXCerebral cortex51.99
37
Tnpo3HIPHippocampal region53.09
59.78
Tnpo3HPFHippocampal formation58.62
57.31
Tnpo3HYHypothalamus30.57
22.88
Tnpo3LSXLateral septal complex29.9
20.42
Tnpo3MBMidbrain20.49
16.62
Tnpo3MYMedulla30.52
30.39
Tnpo3OLFOlfactory bulb52.54
40.09
Tnpo3PPons27
24.75
Tnpo3PALPallidum26.81
22.23
Tnpo3RHPRetrohippocampal region74.18
57.58
Tnpo3sAMYStriatum-like amygdalar nuclei36.38
25.77
Tnpo3STRStriatum23.86
16.72
Tnpo3STRdStriatum dorsal region17.95
12.36
Tnpo3STRvStriatum ventral region29.92
21.18
Tnpo3THThalamus38.41
28.52
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00001705 19 801 819 DLIHTGVANDHEEDFELRK Peptide Atlas
TNPO3_HUMAN_803 20 803 822 SQVVIPILQWAIASTTLDHR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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