AutismKB 2.0

Annotation Detail for FOSB


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Basic Information Top
Gene Symbol:FOSB ( AP-1,DKFZp686C0818,G0S3,GOS3,GOSB,MGC42291 )
Gene Full Name: FBJ murine osteosarcoma viral oncogene homolog B
Band: 19q13.32
Quick LinksEntrez ID:2354; OMIM: 164772; Uniprot ID:FOSB_HUMAN; ENSEMBL ID: ENSG00000125740; HGNC ID: 3797
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst0 / 623190 
fetus17 / 56401230
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult170 / 193912187
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma11 / 82823132
colorectal tumor5 / 11424643
esophageal tumor0 / 172900 
gastrointestinal tumor6 / 11936950
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor14 / 136302102
kidney tumor0 / 689590 
leukemia6 / 9584262
liver tumor0 / 963590 
lung tumor4 / 10312738
lymphoma0 / 717550 
non-neoplasia17 / 97250174
normal249 / 336030774
ovarian tumor5 / 7668265
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer3 / 10268029
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue7 / 13106534
adrenal gland3 / 3319790
ascites1 / 4001524
bladder0 / 297570 
blood11 / 12347889
bone1 / 7165513
bone marrow0 / 488010 
brain36 / 110098932
cervix1 / 4817120
connective tissue26 / 149255174
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus0 / 202090 
eye7 / 21105433
heart1 / 8962611
intestine19 / 23447281
kidney1 / 2117774
larynx1 / 2414541
liver4 / 20774319
lung41 / 336974121
lymph0 / 442700 
lymph node1 / 9161010
mammary gland6 / 15327139
mouth12 / 67052178
muscle3 / 10771527
nerve0 / 157680 
ovary8 / 10205178
pancreas18 / 21481283
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta13 / 28082546
prostate10 / 18934552
salivary gland0 / 201550 
skin0 / 2105740 
spleen5 / 5395292
stomach9 / 9661993
testis29 / 33044287
thymus1 / 8113112
thyroid18 / 47473379
tonsil2 / 16999117
trachea291 / 524135552
umbilical cord0 / 136800 
uterus108 / 232878463
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202768_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.35
Adipocyte5.15
AdrenalCortex341.1
Adrenalgland15.45
Amygdala7.05
Appendix5.95
AtrioventricularNode4.6
BDCA4+_DentriticCells798.15
Bonemarrow5.4
BronchialEpithelialCells4.75
CD105+_Endothelial652.3
CD14+_Monocytes480.5
CD19+_BCells(neg._sel.)8
CD33+_Myeloid6687.05
CD34+1528.15
CD4+_Tcells23.3
CD56+_NKCells45.75
CD71+_EarlyErythroid14.05
CD8+_Tcells13.5
CardiacMyocytes7.05
Caudatenucleus5.35
Cerebellum4.5
CerebellumPeduncles5.65
CiliaryGanglion97
CingulateCortex5.65
Colorectaladenocarcinoma98.35
DorsalRootGanglion4.65
FetalThyroid5.2
Fetalbrain5.25
Fetalliver4.5
Fetallung7.7
GlobusPallidus4
Heart7.05
Hypothalamus7.1
Kidney4.25
Leukemia_chronicMyelogenousK-5624.7
Leukemia_promyelocytic-HL-604.8
Leukemialymphoblastic(MOLT-4)4.55
Liver7.4
Lung35.25
Lymphnode16
Lymphoma_burkitts(Daudi)7.05
Lymphoma_burkitts(Raji)7.4
MedullaOblongata5.85
OccipitalLobe5.5
OlfactoryBulb6.1
Ovary3.65
Pancreas4.9
PancreaticIslet6.5
ParietalLobe5.65
Pituitary10.65
Placenta36.15
Pons4.9
PrefrontalCortex6.85
Prostate11.15
Salivarygland5.05
SkeletalMuscle6.95
Skin8.8
SmoothMuscle5.55
Spinalcord39.3
SubthalamicNucleus4.8
SuperiorCervicalGanglion6.85
TemporalLobe4.8
Testis4.5
TestisGermCell71.85
TestisIntersitial6.4
TestisLeydigCell5.3
TestisSeminiferousTubule5.25
Thalamus5.85
Thymus11.8
Thyroid331.65
Tongue5.55
Tonsil29.75
Trachea158.75
TrigeminalGanglion13.3
Uterus15.7
UterusCorpus28.55
WholeBlood6.05
Wholebrain5.25
colon5.25
pineal_day50.66
pineal_night29.82
retina25.45
small_intestine5.55
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P429998
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.28 ± 0.44
Basal Forebrain4.94 ± 0.64
Basal Part of Pons5.15 ± 0.72
Cerebellar Cortex4.01 ± 0.55
Cerebellar Nuclei4.95 ± 0.6
Claustrum5.37 ± 0.57
Epithalamus4.91 ± 0.86
Frontal Lobe4.58 ± 0.7
Globus Pallidus3.08 ± 1.18
Hypothalamus4.67 ± 1
Insula4.78 ± 0.6
Limbic Lobe4.81 ± 0.88
Mesencephalon4.58 ± 0.7
Myelencephalon4.61 ± 0.78
Occipital Lobe5.68 ± 0.6
Parietal Lobe5.15 ± 0.62
Pontine Tegmentum4.62 ± 1.02
Striatum5.44 ± 0.95
Subthalamus4.43 ± 1.13
Temporal Lobe4.76 ± 0.69
Thalamus4.14 ± 0.66
White Matter2.61 ± 0.64
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
FosbLSXLateral septal complex7.75
8.58
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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