AutismKB 2.0

Annotation Detail for TTC33


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Basic Information Top
Gene Symbol:TTC33 ( OSRF )
Gene Full Name: tetratricopeptide repeat domain 33
Band: 5p13.1
Quick LinksEntrez ID:23548; OMIM: NA; Uniprot ID:TTC33_HUMAN; ENSEMBL ID: ENSG00000113638; HGNC ID: 29959
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst2 / 6231932
fetus17 / 56401230
neonate4 / 31097128
infant1 / 2362042
juvenile1 / 5555617
adult54 / 193912127
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor2 / 3436658
chondrosarcoma1 / 8282312
colorectal tumor1 / 1142468
esophageal tumor1 / 1729057
gastrointestinal tumor0 / 1193690 
germ cell tumor7 / 26384526
glioma3 / 10688328
head and neck tumor0 / 1363020 
kidney tumor2 / 6895929
leukemia1 / 9584210
liver tumor4 / 9635941
lung tumor0 / 1031270 
lymphoma2 / 7175527
non-neoplasia5 / 9725051
normal116 / 336030734
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS6 / 12568047
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood5 / 12347840
bone1 / 7165513
bone marrow1 / 4880120
brain71 / 110098964
cervix2 / 4817141
connective tissue1 / 1492556
ear1 / 1621261
embryonic tissue5 / 21572223
esophagus1 / 2020949
eye3 / 21105414
heart1 / 8962611
intestine3 / 23447212
kidney9 / 21177742
larynx1 / 2414541
liver10 / 20774348
lung2 / 3369745
lymph0 / 442700 
lymph node3 / 9161032
mammary gland4 / 15327126
mouth0 / 670520 
muscle3 / 10771527
nerve2 / 15768126
ovary2 / 10205119
pancreas5 / 21481223
parathyroid1 / 2053948
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta4 / 28082514
prostate2 / 18934510
salivary gland2 / 2015599
skin2 / 2105749
spleen0 / 539520 
stomach1 / 9661910
testis8 / 33044224
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea3 / 5241357
umbilical cord0 / 136800 
uterus4 / 23287817
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219421_at
Cell line Expression level Expression bar
721_B_lymphoblasts14.6
Adipocyte9.4
AdrenalCortex12.95
Adrenalgland8.35
Amygdala18.1
Appendix14.55
AtrioventricularNode10.7
BDCA4+_DentriticCells10.85
Bonemarrow10.55
BronchialEpithelialCells8.9
CD105+_Endothelial18.05
CD14+_Monocytes13.2
CD19+_BCells(neg._sel.)9.8
CD33+_Myeloid11.35
CD34+18.6
CD4+_Tcells9.45
CD56+_NKCells13.55
CD71+_EarlyErythroid13.35
CD8+_Tcells10.9
CardiacMyocytes24.1
Caudatenucleus8.7
Cerebellum8.2
CerebellumPeduncles11.75
CiliaryGanglion10.6
CingulateCortex10.8
Colorectaladenocarcinoma9.45
DorsalRootGanglion9.75
FetalThyroid10.7
Fetalbrain31.1
Fetalliver9
Fetallung7.85
GlobusPallidus7.5
Heart14.85
Hypothalamus10.3
Kidney8.5
Leukemia_chronicMyelogenousK-5628.55
Leukemia_promyelocytic-HL-6013.55
Leukemialymphoblastic(MOLT-4)11.55
Liver16.15
Lung10.4
Lymphnode7.9
Lymphoma_burkitts(Daudi)13.8
Lymphoma_burkitts(Raji)17.15
MedullaOblongata8.65
OccipitalLobe8.6
OlfactoryBulb7.65
Ovary8.5
Pancreas8.25
PancreaticIslet10.7
ParietalLobe11.2
Pituitary11.7
Placenta9.15
Pons10.4
PrefrontalCortex13.65
Prostate11.8
Salivarygland8.7
SkeletalMuscle16.5
Skin9.7
SmoothMuscle10.95
Spinalcord9.95
SubthalamicNucleus9.05
SuperiorCervicalGanglion20.3
TemporalLobe9.9
Testis8.15
TestisGermCell7.9
TestisIntersitial8
TestisLeydigCell10.45
TestisSeminiferousTubule8.7
Thalamus10.4
Thymus7
Thyroid16.55
Tongue11.5
Tonsil9.8
Trachea7.85
TrigeminalGanglion16
Uterus8.75
UterusCorpus11.5
WholeBlood18.35
Wholebrain10.7
colon10
pineal_day18.58
pineal_night20.22
retina16.225
small_intestine9.35
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P405981
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.62 ± 0.43
Basal Forebrain5.74 ± 0.66
Basal Part of Pons5.85 ± 0.23
Cerebellar Cortex5.71 ± 0.23
Cerebellar Nuclei5.45 ± 0.38
Claustrum6.06 ± 0.35
Epithalamus5.28 ± 0.59
Frontal Lobe5.44 ± 0.38
Globus Pallidus4.34 ± 0.44
Hypothalamus5.6 ± 0.31
Insula5.49 ± 0.44
Limbic Lobe5.54 ± 0.46
Mesencephalon5.38 ± 0.55
Myelencephalon5.46 ± 0.45
Occipital Lobe5.8 ± 0.39
Parietal Lobe5.76 ± 0.35
Pontine Tegmentum5.54 ± 0.34
Striatum5.48 ± 0.37
Subthalamus5.29 ± 0.31
Temporal Lobe5.56 ± 0.37
Thalamus5.51 ± 0.35
White Matter4.5 ± 0.25
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ttc33CBCerebellum11.38
14.95
Ttc33CTXCerebral cortex49.57
38.52
Ttc33HIPHippocampal region31.65
33.68
Ttc33HPFHippocampal formation34.3
32.82
Ttc33HYHypothalamus10.57
9.54
Ttc33LSXLateral septal complex1.81
1.6
Ttc33MBMidbrain25.84
25.46
Ttc33MYMedulla46.9
55.32
Ttc33OLFOlfactory bulb30.28
24.62
Ttc33PPons31.54
36.12
Ttc33PALPallidum20.7
20.93
Ttc33RHPRetrohippocampal region41.03
33.28
Ttc33sAMYStriatum-like amygdalar nuclei19.2
13.81
Ttc33STRStriatum16.33
11.51
Ttc33STRdStriatum dorsal region18.08
12.8
Ttc33STRvStriatum ventral region15.07
10.01
Ttc33THThalamus18.3
15.69
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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