AutismKB 2.0

Annotation Detail for TSPAN12


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:TSPAN12 ( EVR5,NET-2,NET2,TM4SF12 )
Gene Full Name: tetraspanin 12
Band: 7q31.31
Quick LinksEntrez ID:23554; OMIM: 613138; Uniprot ID:TSN12_HUMAN; ENSEMBL ID: ENSG00000106025; HGNC ID: 21641
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst1 / 6231916
fetus15 / 56401226
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult64 / 193912133
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor3 / 12794234
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor14 / 26384553
glioma1 / 1068839
head and neck tumor4 / 13630229
kidney tumor2 / 6895929
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia4 / 9725041
normal124 / 336030736
ovarian tumor2 / 7668226
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor11 / 12519187
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland15 / 33197451
ascites0 / 400150 
bladder6 / 29757201
blood0 / 1234780 
bone1 / 7165513
bone marrow0 / 488010 
brain30 / 110098927
cervix2 / 4817141
connective tissue9 / 14925560
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus0 / 202090 
eye10 / 21105447
heart6 / 8962666
intestine7 / 23447229
kidney14 / 21177766
larynx0 / 241450 
liver1 / 2077434
lung9 / 33697426
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth3 / 6705244
muscle6 / 10771555
nerve0 / 157680 
ovary2 / 10205119
pancreas5 / 21481223
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta6 / 28082521
prostate7 / 18934536
salivary gland0 / 201550 
skin0 / 2105740 
spleen6 / 53952111
stomach0 / 966190 
testis13 / 33044239
thymus1 / 8113112
thyroid2 / 4747342
tonsil0 / 169990 
trachea6 / 52413114
umbilical cord0 / 136800 
uterus7 / 23287830
vascular5 / 5178096
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219274_at
Cell line Expression level Expression bar
721_B_lymphoblasts9.3
Adipocyte7.55
AdrenalCortex15.05
Adrenalgland47
Amygdala7.95
Appendix14.35
AtrioventricularNode13.85
BDCA4+_DentriticCells8
Bonemarrow9.8
BronchialEpithelialCells7.25
CD105+_Endothelial8.45
CD14+_Monocytes9.6
CD19+_BCells(neg._sel.)8.25
CD33+_Myeloid9.9
CD34+13.4
CD4+_Tcells8
CD56+_NKCells8.75
CD71+_EarlyErythroid8.2
CD8+_Tcells6.75
CardiacMyocytes18.05
Caudatenucleus7.2
Cerebellum6.45
CerebellumPeduncles10.4
CiliaryGanglion10.1
CingulateCortex8.7
Colorectaladenocarcinoma7.7
DorsalRootGanglion12.7
FetalThyroid11.4
Fetalbrain7.85
Fetalliver11.2
Fetallung20.65
GlobusPallidus7.8
Heart17.35
Hypothalamus8.5
Kidney23.55
Leukemia_chronicMyelogenousK-5627.1
Leukemia_promyelocytic-HL-606.6
Leukemialymphoblastic(MOLT-4)5.9
Liver16.05
Lung8.75
Lymphnode6.7
Lymphoma_burkitts(Daudi)11
Lymphoma_burkitts(Raji)12.65
MedullaOblongata6.95
OccipitalLobe7
OlfactoryBulb6.05
Ovary7.5
Pancreas9.3
PancreaticIslet10.9
ParietalLobe10.15
Pituitary9.95
Placenta7.95
Pons8.75
PrefrontalCortex9.05
Prostate15.8
Salivarygland9.2
SkeletalMuscle14.95
Skin10.35
SmoothMuscle9.2
Spinalcord8.2
SubthalamicNucleus11.05
SuperiorCervicalGanglion21.75
TemporalLobe7.95
Testis6.55
TestisGermCell6.2
TestisIntersitial8.6
TestisLeydigCell9.55
TestisSeminiferousTubule7.05
Thalamus8.8
Thymus5.75
Thyroid164.2
Tongue11.45
Tonsil8.3
Trachea7.8
TrigeminalGanglion16.15
Uterus8.9
UterusCorpus9.3
WholeBlood8.3
Wholebrain6.45
colon92.75
pineal_day9.56
pineal_night9.42
retina10.075
small_intestine121.2
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P145984
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.14 ± 0.49
Basal Forebrain5.67 ± 0.28
Basal Part of Pons5.15 ± 0.52
Cerebellar Cortex4.88 ± 0.5
Cerebellar Nuclei5.69 ± 0.54
Claustrum4.47 ± 0.85
Epithalamus4.42 ± 0.94
Frontal Lobe5.2 ± 0.7
Globus Pallidus6.34 ± 0.55
Hypothalamus5.54 ± 0.56
Insula5.08 ± 0.47
Limbic Lobe4.86 ± 0.73
Mesencephalon5.34 ± 0.78
Myelencephalon5.29 ± 0.72
Occipital Lobe5.82 ± 0.57
Parietal Lobe5.36 ± 0.57
Pontine Tegmentum5.49 ± 0.69
Striatum6.13 ± 0.44
Subthalamus5.56 ± 0.22
Temporal Lobe4.98 ± 0.62
Thalamus5.86 ± 0.68
White Matter2.57 ± 0.42
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Tspan12CBCerebellum1.12
1.79
Tspan12CTXCerebral cortex0.8
0.88
Tspan12HIPHippocampal region0.48
0.51
Tspan12HPFHippocampal formation0.49
0.45
Tspan12HYHypothalamus0.67
0.89
Tspan12LSXLateral septal complex0.18
0.21
Tspan12MBMidbrain0.97
1.33
Tspan12MYMedulla2.04
2.97
Tspan12OLFOlfactory bulb1.35
1.77
Tspan12PPons1.11
1.71
Tspan12PALPallidum0.24
0.34
Tspan12RHPRetrohippocampal region0.51
0.37
Tspan12sAMYStriatum-like amygdalar nuclei0.11
0.6
Tspan12STRStriatum0.19
0.24
Tspan12STRdStriatum dorsal region0.2
0.23
Tspan12STRvStriatum ventral region0.19
0.14
Tspan12THThalamus1.32
1.29
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved