AutismKB 2.0

Annotation Detail for GTPBP4


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Basic Information Top
Gene Symbol:GTPBP4 ( CRFG,FLJ10686,FLJ10690,FLJ39774,NGB,NOG1 )
Gene Full Name: GTP binding protein 4
Band: 10p15.3
Quick LinksEntrez ID:23560; OMIM: NA; Uniprot ID:NOG1_HUMAN; ENSEMBL ID: ENSG00000107937; HGNC ID: 21535
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body5 / 7076170
blastocyst3 / 6231948
fetus46 / 56401281
neonate9 / 31097289
infant5 / 23620211
juvenile15 / 55556269
adult112 / 193912157
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma2 / 17475114
breast (mammary gland) tumor5 / 9417853
cervical tumor2 / 3436658
chondrosarcoma4 / 8282348
colorectal tumor6 / 11424652
esophageal tumor2 / 17290115
gastrointestinal tumor22 / 119369184
germ cell tumor35 / 263845132
glioma2 / 10688318
head and neck tumor8 / 13630258
kidney tumor4 / 6895958
leukemia9 / 9584293
liver tumor20 / 96359207
lung tumor5 / 10312748
lymphoma3 / 7175541
non-neoplasia5 / 9725051
normal215 / 336030763
ovarian tumor2 / 7668226
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS27 / 125680214
prostate cancer6 / 10268058
retinoblastoma14 / 46356302
skin tumor15 / 124949120
soft tissue/muscle tissue tumor13 / 125191103
uterine tumor7 / 9025777
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland4 / 33197120
ascites7 / 40015174
bladder3 / 29757100
blood9 / 12347872
bone3 / 7165541
bone marrow3 / 4880161
brain87 / 110098979
cervix3 / 4817162
connective tissue12 / 14925580
ear1 / 1621261
embryonic tissue13 / 21572260
esophagus2 / 2020998
eye18 / 21105485
heart11 / 89626122
intestine16 / 23447268
kidney17 / 21177780
larynx1 / 2414541
liver23 / 207743110
lung18 / 33697453
lymph1 / 4427022
lymph node10 / 91610109
mammary gland5 / 15327132
mouth9 / 67052134
muscle2 / 10771518
nerve0 / 157680 
ovary3 / 10205129
pancreas5 / 21481223
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta10 / 28082535
prostate13 / 18934568
salivary gland2 / 2015599
skin25 / 210574118
spleen3 / 5395255
stomach16 / 96619165
testis25 / 33044275
thymus3 / 8113136
thyroid1 / 4747321
tonsil0 / 169990 
trachea6 / 52413114
umbilical cord1 / 1368073
uterus17 / 23287872
vascular11 / 51780212
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218238_at
Cell line Expression level Expression bar
721_B_lymphoblasts439.65
Adipocyte41.9
AdrenalCortex79.35
Adrenalgland17.85
Amygdala34.75
Appendix20.85
AtrioventricularNode26.4
BDCA4+_DentriticCells222.3
Bonemarrow26.35
BronchialEpithelialCells214.3
CD105+_Endothelial375.6
CD14+_Monocytes114.8
CD19+_BCells(neg._sel.)121.7
CD33+_Myeloid212.8
CD34+410.55
CD4+_Tcells190.65
CD56+_NKCells187.75
CD71+_EarlyErythroid78.1
CD8+_Tcells163.55
CardiacMyocytes81.3
Caudatenucleus21.8
Cerebellum11.75
CerebellumPeduncles24.8
CiliaryGanglion16.2
CingulateCortex22.05
Colorectaladenocarcinoma29.75
DorsalRootGanglion24.8
FetalThyroid25.95
Fetalbrain25.1
Fetalliver33.8
Fetallung28.1
GlobusPallidus23.7
Heart34.5
Hypothalamus31.4
Kidney13.6
Leukemia_chronicMyelogenousK-562199.8
Leukemia_promyelocytic-HL-60179.05
Leukemialymphoblastic(MOLT-4)100.25
Liver18.35
Lung18.6
Lymphnode31.25
Lymphoma_burkitts(Daudi)187
Lymphoma_burkitts(Raji)126.05
MedullaOblongata22.4
OccipitalLobe28.9
OlfactoryBulb25
Ovary24.15
Pancreas22.65
PancreaticIslet41.9
ParietalLobe36.4
Pituitary34.4
Placenta24.75
Pons15.65
PrefrontalCortex28.15
Prostate28.7
Salivarygland34.8
SkeletalMuscle58.65
Skin31.75
SmoothMuscle92.1
Spinalcord25.6
SubthalamicNucleus29
SuperiorCervicalGanglion34.65
TemporalLobe22.3
Testis28.9
TestisGermCell54.35
TestisIntersitial60.75
TestisLeydigCell57.25
TestisSeminiferousTubule53.55
Thalamus24
Thymus20.6
Thyroid36.75
Tongue31.65
Tonsil29.35
Trachea17.9
TrigeminalGanglion53.3
Uterus34.35
UterusCorpus32.2
WholeBlood29.9
Wholebrain15.1
colon27.35
pineal_day125.38
pineal_night110.5
retina39.75
small_intestine26.5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_2202_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.44 ± 0.18
Basal Forebrain7.49 ± 0.23
Basal Part of Pons7.41 ± 0.24
Cerebellar Cortex7.29 ± 0.18
Cerebellar Nuclei7.46 ± 0.24
Claustrum7.44 ± 0.37
Epithalamus7.29 ± 0.08
Frontal Lobe7.36 ± 0.25
Globus Pallidus7.71 ± 0.14
Hypothalamus7.44 ± 0.17
Insula7.41 ± 0.23
Limbic Lobe7.52 ± 0.25
Mesencephalon7.48 ± 0.25
Myelencephalon7.38 ± 0.24
Occipital Lobe7.47 ± 0.23
Parietal Lobe7.42 ± 0.2
Pontine Tegmentum7.39 ± 0.26
Striatum7.58 ± 0.23
Subthalamus7.2 ± 0.3
Temporal Lobe7.41 ± 0.24
Thalamus7.37 ± 0.21
White Matter7.86 ± 0.17
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Gtpbp4CBCerebellum7.99
6.66
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00011713 12 170 181 TLLLCGYPNVGK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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